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Quoted phrase not found in phrase index: "steoroids"
Page 1
Medicinal-Chemistry-Driven Approach to 2-Substituted Benzoxazole-Estradiol Chimeras: Synthesis, Anticancer Activity, and Early ADME Profile.
Kovács F, Huliák I, Árva H, Kiricsi M, Erdős D, Kocsis M, Takács G, Balogh GT, Frank É. Kovács F, et al. ChemMedChem. 2023 Nov 16;18(22):e202300352. doi: 10.1002/cmdc.202300352. Epub 2023 Oct 2. ChemMedChem. 2023. PMID: 37727903
The target compounds were prepared from steroidal 2-aminophenol precursors by heterocycle formation or functional group interconversion (FGI) strategies. ...Pharmacological tests and LLE metric revealed that some derivatives, especially the 2-(4-ethylpiperazin-1-yl) …
The target compounds were prepared from steroidal 2-aminophenol precursors by heterocycle formation or functional group interc …
Final report on the safety assessment of 6-Amino-m-Cresol, 6-Amino-o-Cresol, 4-Amino-m-Cresol, 5-Amino-4-Chloro-o-Cresol, 5-Amino-6-Chloro-o-Cresol, and 4-Chloro-2-Aminophenol.
[No authors listed] [No authors listed] Int J Toxicol. 2004;23 Suppl 2:1-22. doi: 10.1080/10915810490499037. Int J Toxicol. 2004. PMID: 15513822 Review.
In the absence of systemic toxicity data, however, the available data are insufficient to support the safety of 6-Amino-o-Cresol and 4-Chloro-2-Aminophenol in semipermanent hair dyes. The types of data required for these two ingredients for this use include (1) phys …
In the absence of systemic toxicity data, however, the available data are insufficient to support the safety of 6-Amino-o-Cresol and 4-Chlor …
Advances in the synthetic strategies of benzoxazoles using 2-aminophenol as a precursor: an up-to-date review.
Soni S, Sahiba N, Teli S, Teli P, Agarwal LK, Agarwal S. Soni S, et al. RSC Adv. 2023 Aug 11;13(34):24093-24111. doi: 10.1039/d3ra03871h. eCollection 2023 Aug 4. RSC Adv. 2023. PMID: 37577091 Free PMC article. Review.
The motif exhibits a high possibility of broad substrate scope and functionalization to offer several biological activities like anti-microbial, anti-fungal, anti-cancer, anti-oxidant, anti-inflammatory effects, and so on. There has been a large upsurge in the synthesis of …
The motif exhibits a high possibility of broad substrate scope and functionalization to offer several biological activities like anti-microb …
Occurrence and partitioning of bisphenol analogues, triclocarban, and triclosan in seawater and sediment from East China Sea.
Xie J, Zhao N, Zhang Y, Hu H, Zhao M, Jin H. Xie J, et al. Chemosphere. 2022 Jan;287(Pt 2):132218. doi: 10.1016/j.chemosphere.2021.132218. Epub 2021 Sep 8. Chemosphere. 2022. PMID: 34509769
Bisphenol analogues (BPs), triclocarban (TCC), and triclosan (TCS) are well-known environmental endocrine disrupters. Many studies have characterized their occurrence in the freshwater environment. ...For the first time, this study reports the environmental occurrence of b …
Bisphenol analogues (BPs), triclocarban (TCC), and triclosan (TCS) are well-known environmental endocrine disrupters. Many studies ha …
Fractionated Sonodynamic Therapy Using Gold@Poly(ortho-aminophenol) Nanoparticles and Multistep Low-Intensity Ultrasound Irradiation to Treat Melanoma Cancer: In Vitro and In Vivo Studies.
Daneshvar F, Salehi F, Kayani Z, Sattarahmady N, DehdariVais R, Azarpira N. Daneshvar F, et al. Ultrasound Med Biol. 2023 May;49(5):1299-1308. doi: 10.1016/j.ultrasmedbio.2023.01.017. Epub 2023 Feb 26. Ultrasound Med Biol. 2023. PMID: 36849267
OBJECTIVE: Cancer treatment using ultrasound irradiation with low intensities along with a sonosensitizer has been found to have significant advantages, such as high penetration depth in tissues, non-invasive therapeutic character, minor side effects, good patient adherenc …
OBJECTIVE: Cancer treatment using ultrasound irradiation with low intensities along with a sonosensitizer has been found to have sign …
Urinary paracetamol (4-acetaminophenol) and its isomer 2-acetaminophenol of Chinese pregnant women: Exposure characteristics and association with oxidative stress biomarkers.
Li X, Xu L, Wan Y, Li J, Qian X, Xia W, He Z, Zheng T, Xu S, Li Y. Li X, et al. Sci Total Environ. 2022 Dec 15;852:158375. doi: 10.1016/j.scitotenv.2022.158375. Epub 2022 Aug 29. Sci Total Environ. 2022. PMID: 36049689
N-Acetyl-4-aminophenol (NA4AP, paracetamol/acetaminophen), a widely used pharmaceutical, is ubiquitous in urine samples of general population, raising concern about human health risks; oxidative stress is considered to be a mechanism for its toxicities. N-Acetyl-2-amino …
N-Acetyl-4-aminophenol (NA4AP, paracetamol/acetaminophen), a widely used pharmaceutical, is ubiquitous in urine samples of general populatio …
p-Cymene Complexes of Ruthenium(II) as Antitumor Agents.
Pujante-Galián MA, Pérez SA, Montalbán MG, Carissimi G, Fuster MG, Víllora G, García G. Pujante-Galián MA, et al. Molecules. 2020 Oct 31;25(21):5063. doi: 10.3390/molecules25215063. Molecules. 2020. PMID: 33142775 Free PMC article.
In this work, the cytotoxic behavior of six ruthenium(II) complexes of stoichiometry [(eta(6)-p-cymene)RuCl(2)L] (I-VI), L = 4-cyanopyridine (I), 2-aminophenol (II), 4-aminophenol (III), pyridazine (IV), and [(eta(6)-p-cymene)RuClL(2)]PF(6); L = cyanopyridine (V), L …
In this work, the cytotoxic behavior of six ruthenium(II) complexes of stoichiometry [(eta(6)-p-cymene)RuCl(2)L] (I-VI), L = 4-cyanopyridine …
Synthesis and biological evaluation of new N-benzylpyridinium-based benzoheterocycles as potential anti-Alzheimer's agents.
Salehi N, Mirjalili BBF, Nadri H, Abdolahi Z, Forootanfar H, Samzadeh-Kermani A, Küçükkılınç TT, Ayazgok B, Emami S, Haririan I, Sharifzadeh M, Foroumadi A, Khoobi M. Salehi N, et al. Bioorg Chem. 2019 Mar;83:559-568. doi: 10.1016/j.bioorg.2018.11.010. Epub 2018 Nov 13. Bioorg Chem. 2019. PMID: 30471578
The title compounds 4a-q were conveniently synthesized via condensation reaction of 1,2-phenylenediamine, 2-aminophenol or 2-aminothiophenol with pyridin-4-carbalehyde, followed by N-benzylation using various benzyl halides. ...
The title compounds 4a-q were conveniently synthesized via condensation reaction of 1,2-phenylenediamine, 2-aminophenol or 2-a …
Design, Synthesis, and Biological Evaluation of Some Novel o-aminophenol Derivatives.
Nguyen DV, Tran LD, Vu PUN, Meervelt LV, Nguyen MNT, Ngo AL, Duong HQ. Nguyen DV, et al. Curr Org Synth. 2025;22(6):754-768. doi: 10.2174/0115701794360303250109065121. Curr Org Synth. 2025. PMID: 39950292
Cytotoxicity was evaluated on KB, HepG2, A549, and MCF7 cancer cell lines. RESULTS: Six synthesized compounds 5b, 5c, 5g, 6b, 6c, 6g exhibited unusual doublet signals in the H8 region of the (1)H NMR spectrum, attributed to atropisomer formation. ...
Cytotoxicity was evaluated on KB, HepG2, A549, and MCF7 cancer cell lines. RESULTS: Six synthesized compounds 5b, 5c, 5g, 6b, 6c, 6g …
Reactions of cobalt(ii) chloride and cobalt(ii) acetate with hemisalen-type ligands: ligand transformation, oxidation of cobalt and complex formation. Preliminary study on the cytotoxicity of Co(ii) and Co(iii) hemisalen complexes.
Siedzielnik M, Pawłowska M, Daśko M, Kleinschmidt H, Dołęga A. Siedzielnik M, et al. RSC Adv. 2023 Mar 16;13(13):8830-8843. doi: 10.1039/d2ra07089h. eCollection 2023 Mar 14. RSC Adv. 2023. PMID: 36936819 Free PMC article.
The latter complex formed in a cobalt(ii) acetate reaction with a hemisalen HL5 derived from oVP and 2-aminophenol. The molecular structures of all compounds were confirmed by X-ray diffraction, and the cytotoxicity of Co(ii) and Co(iii) complexes towards cancer …
The latter complex formed in a cobalt(ii) acetate reaction with a hemisalen HL5 derived from oVP and 2-aminophenol. The molecu …
52 results