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113 results

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Page 1
Nitrite facilitated transformation of halophenols in ice.
Chen J, Yang P, Chen J, Gao B, Lu J. Chen J, et al. Water Res. 2024 Oct 1;263:122158. doi: 10.1016/j.watres.2024.122158. Epub 2024 Jul 26. Water Res. 2024. PMID: 39088882
When 10 mu halophenol was treated by freezing in the presence of 5 mu NO(2)(-), the total yields of nitrated products reached 2.4 mu and 1.4 mu within 12 h for 2-chlorophenol (2CP) and 2-bromophenol (2BP), respectively. NO(+) drove oxidative coupling reactions, …
When 10 mu halophenol was treated by freezing in the presence of 5 mu NO(2)(-), the total yields of nitrated products reached 2.4 mu and …
Identification of 2-bromohydroquinone as a metabolite of bromobenzene and o-bromophenol: implications for bromobenzene-induced nephrotoxicity.
Lau SS, Monks TJ, Gillette JR. Lau SS, et al. J Pharmacol Exp Ther. 1984 Aug;230(2):360-6. J Pharmacol Exp Ther. 1984. PMID: 6747840
Covalent binding of o-bromophenol to rat liver microsomes was inhibited by glutathione and ascorbate but not by superoxide dismutase or catalase. Liver microsomes converted o-bromophenol to 2-bromohydroquinone and covalently bound material, whereas kid …
Covalent binding of o-bromophenol to rat liver microsomes was inhibited by glutathione and ascorbate but not by superoxide dis …
The metabolic fate and effects of 2-Bromophenol in male Sprague-Dawley rats.
Adesina-Georgiadis KN, Gray N, Plumb RS, Thompson DF, Holmes E, Nicholson JK, Wilson ID. Adesina-Georgiadis KN, et al. Xenobiotica. 2019 Nov;49(11):1352-1359. doi: 10.1080/00498254.2018.1559376. Epub 2019 Feb 22. Xenobiotica. 2019. PMID: 30557119 Free article.
Urine was collected for seven days and samples analysed using (1 )H NMR spectroscopy, inductively coupled plasma (ICP)MS, and UPLC-MS.3. (1 )H NMR spectroscopy of the urine samples showed that, at these doses, 2-bromophenol had little effect on endogenous metabolite …
Urine was collected for seven days and samples analysed using (1 )H NMR spectroscopy, inductively coupled plasma (ICP)MS, and UPLC-MS.3. (1 …
The mechanism of formation of o-bromophenol from bromobenzene.
Monks TJ, Lau SS, Pohl LR, Gillette JR. Monks TJ, et al. Drug Metab Dispos. 1984 Mar-Apr;12(2):193-8. Drug Metab Dispos. 1984. PMID: 6144485
Both o-bromophenol and p-bromophenol are formed from bromobenzene in rat liver microsomes. ...The lack of a significant isotope effect indicates that the hydroxylation of bromobenzene to o-bromophenol is not by a direct insertion mechanism. Furthermore …
Both o-bromophenol and p-bromophenol are formed from bromobenzene in rat liver microsomes. ...The lack of a significant isotop …
Nitrosation of phenolic compounds: inhibition and enhancement.
González-Mancebo S, García-Santos MP, Hernández-Benito J, Calle E, Casado J. González-Mancebo S, et al. J Agric Food Chem. 1999 Jun;47(6):2235-40. doi: 10.1021/jf981094n. J Agric Food Chem. 1999. PMID: 10794616
The nitrosation of phenol, m-, o-, and p-cresol, 2,3-, 3,5-, and 2, 6-dimethylphenol, 3,5-di-tert-butylphenol, 2,4,6-trimethylphenol, o-chlorophenol, and o-bromophenol was studied. Kinetic monitoring of the reactions was accomplished by spectrophotometric analysis o …
The nitrosation of phenol, m-, o-, and p-cresol, 2,3-, 3,5-, and 2, 6-dimethylphenol, 3,5-di-tert-butylphenol, 2,4,6-trimethylphenol, o-chlo …
Transformation of bromide and formation of brominated disinfection byproducts in peracetic acid oxidation of phenol.
Meng L, Chen J, Kong D, Ji Y, Lu J, Yin X, Zhou Q. Meng L, et al. Chemosphere. 2022 Mar;291(Pt 1):132698. doi: 10.1016/j.chemosphere.2021.132698. Epub 2021 Oct 26. Chemosphere. 2022. PMID: 34715107
Most of the organic bromines were presented as bromophenols (i.e., 2-bromophenol, 4-bromophenol, and 2,4-dibromophenol), while regulated brominated disinfection byproducts (Br-DBPs, i.e., bromoform and bromoacetic acids) only accounted for a tiny fraction of total o …
Most of the organic bromines were presented as bromophenols (i.e., 2-bromophenol, 4-bromophenol, and 2,4-dibromophenol), while …
Formation of bromochlorodibenzo-p-dioxins and dibenzofurans from the high-temperature oxidation of a mixture of 2-chlorophenol and 2-bromophenol.
Evans CS, Dellinger B. Evans CS, et al. Environ Sci Technol. 2006 May 1;40(9):3036-42. doi: 10.1021/es051905l. Environ Sci Technol. 2006. PMID: 16719108
The homogeneous, gas-phase oxidative thermal degradation of a 50:50 mixture of 2-bromophenol and 2-chlorophenol was studied in a 1 cm i.d., fused silica flow reactor at a concentration of 88 ppm, with a reaction time of 2.0 s, over a temperature range of 300 to 1000 …
The homogeneous, gas-phase oxidative thermal degradation of a 50:50 mixture of 2-bromophenol and 2-chlorophenol was studied in …
Nephrotoxicity of phenolic bromobenzene metabolites in the mouse.
Rush GF, Newton JF, Maita K, Kuo CH, Hook JB. Rush GF, et al. Toxicology. 1984 Apr 2;30(3):259-72. doi: 10.1016/0300-483x(84)90097-0. Toxicology. 1984. PMID: 6710548
Bromobenzene, at doses greater than 5.7 mmol/kg, produced renal proximal tubular necrosis and renal functional changes in mice. p-Bromophenol and o-bromophenol were the major urinary phenolic bromobenzene metabolites although m-bromophenol and 4-bromocatechol were a …
Bromobenzene, at doses greater than 5.7 mmol/kg, produced renal proximal tubular necrosis and renal functional changes in mice. p-Bromopheno …
Investigation on the formation mechanism of main products from TBBPA pyrolysis using DFT method.
Mu X, Wang Y, Huang J, Lan L, Wang H, Xu W, Li X. Mu X, et al. Chemosphere. 2023 Apr;320:138045. doi: 10.1016/j.chemosphere.2023.138045. Epub 2023 Feb 2. Chemosphere. 2023. PMID: 36736836
During the pyrolysis of TBBPA, para-position Br atom of polybrominated phenol is easier to be removed and the energy barriers of rate-determining steps of the optimal reaction paths for the formation of 2,4,6-tribromophenol, 2,6-dibromophenol, 2,4-dibromophenol, 2-bromo …
During the pyrolysis of TBBPA, para-position Br atom of polybrominated phenol is easier to be removed and the energy barriers of rate-determ …
Comparative cytotoxicity, endocrine-disrupting effects, oxidative stress of halophenolic disinfection byproducts and the underlying molecular mechanisms revealed by transcriptome analysis.
Li X, Gao X, Li A, Xu S, Zhou Q, Zhang L, Pan Y, Shi W, Song M, Shi P. Li X, et al. Water Res. 2023 Feb 1;229:119458. doi: 10.1016/j.watres.2022.119458. Epub 2022 Dec 4. Water Res. 2023. PMID: 36516492
Furthermore, all of the halophenolic DBPs except for 2-chlorophenol (2-CP) and 2-bromophenol (2-BP) significantly increased the levels of reactive oxygen species (ROS) or 8-hydroxydeoxyguanosine (8-OHdG) in HepG2 cells. ...
Furthermore, all of the halophenolic DBPs except for 2-chlorophenol (2-CP) and 2-bromophenol (2-BP) significantly incre …
113 results