Purified compounds from marine organism sea pen induce apoptosis in human breast cancer cell MDA-MB-231 and cervical cancer cell Hela.
Sharifi S, Mostafavi PG, Tarasi R, Moradi AM, Givianrad MH, Farimani MM, Ebrahimi SN, Hamburger M, Niknejad H.
Sharifi S, et al.
Eur J Pharmacol. 2020 Jun 15;877:173075. doi: 10.1016/j.ejphar.2020.173075. Epub 2020 Mar 25.
Eur J Pharmacol. 2020.
PMID: 32222494
The compounds (3beta)-Cholest,5en,3ol (cholesterol) (15 mg), Hexadecanoic acid (2.5 mg) and 2-Hexadecanol (10.7 mg) were identified by GC-MS and NMR. The cytotoxic effects of the compounds were evaluated on Hela and MDA-Mb-231 human cancer cell lines with MTT assay. …
The compounds (3beta)-Cholest,5en,3ol (cholesterol) (15 mg), Hexadecanoic acid (2.5 mg) and 2-Hexadecanol (10.7 mg) were ident …