Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1956 2
1959 1
1965 1
1976 1
1977 2
1978 1
1979 1
1984 2
1986 1
1989 2
1990 2
1992 1
1993 1
1994 1
1995 2
1996 2
1999 1
2000 1
2001 4
2002 4
2003 6
2004 7
2005 3
2006 5
2007 4
2008 10
2009 14
2010 10
2011 16
2012 14
2013 13
2014 14
2015 8
2016 10
2017 9
2018 5
2019 8
2020 12
2021 7
2022 4
2023 10
2024 12
2025 5
2026 5

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

221 results

Results by year

Filters applied: . Clear all
Page 1
6-(2-Hydroxybenzoyl)-5-(pyrrol-2-yl)-3H-pyrrolizine.
Dey SP, Dey DK, Mallik AK, Dahlenburg L. Dey SP, et al. Acta Crystallogr C. 2003 Jun;59(Pt 6):o321-2. doi: 10.1107/s0108270103008394. Epub 2003 May 20. Acta Crystallogr C. 2003. PMID: 12794351
The title compound, 2-hydroxyphenyl 5-(pyrrol-2-yl)-3H-pyrrolizin-6-yl ketone, C(18)H(14)N(2)O(2), was isolated from the base-catalyzed 1:2 condensation of 2-hydroxyacetophenone with pyrrole-2-carbaldehyde. The pyrrole N-H and hydroxybenzoyl O-H groups are hydrogen …
The title compound, 2-hydroxyphenyl 5-(pyrrol-2-yl)-3H-pyrrolizin-6-yl ketone, C(18)H(14)N(2)O(2), was isolated from the base-catalyzed 1:2 …
Multifunctional asymmetric catalysis.
Shibasaki M, Kanai M. Shibasaki M, et al. Chem Pharm Bull (Tokyo). 2001 May;49(5):511-24. doi: 10.1248/cpb.49.511. Chem Pharm Bull (Tokyo). 2001. PMID: 11383599 Free article. Review.
In the first part of this review, the first example of a catalytic enatioselective nitro-Mannich reaction as well as a direct catalytic enantioselective aldol reaction of 2-hydroxyacetophenone using bimetallic complexes is discussed. The new complex, composed of ytt …
In the first part of this review, the first example of a catalytic enatioselective nitro-Mannich reaction as well as a direct catalytic enan …
Alpha-hydroxyketones as inhibitors of urease.
Tanaka T, Kawase M, Tani S. Tanaka T, et al. Bioorg Med Chem. 2004 Jan 15;12(2):501-5. doi: 10.1016/j.bmc.2003.10.017. Bioorg Med Chem. 2004. PMID: 14723968
Of 13 alpha-hydroxyketones (1-13) tested, 2,2'-thenoin (10) (IC(50)=0.18 mM), furoin (9) (IC(50)=0.36 mM), 2-hydroxy-1-phenylethanone (5) (IC(50)=0.47 mM) and acetol (1) (IC(50)=2.9 mM) showed potent inhibitory activity against the enzyme, comparable w …
Of 13 alpha-hydroxyketones (1-13) tested, 2,2'-thenoin (10) (IC(50)=0.18 mM), furoin (9) (IC(50)=0.36 mM), 2-hydroxy-1- …
Highly enantioselective reduction of 2-hydroxy-1-phenylethanone to enantiopure (R)-phenyl-1,2-ethanediol using Saccharomyces cerevisiae of remarkable reaction stability.
Hu Q, Xu Y, Nie Y. Hu Q, et al. Bioresour Technol. 2010 Nov;101(22):8502-8. doi: 10.1016/j.biortech.2010.06.044. Epub 2010 Jul 13. Bioresour Technol. 2010. PMID: 20630745
Saccharomyces cerevisiae JUC15 was successfully obtained by target reaction-oriented screening, which reduced 2-hydroxy-1-phenylethanone (HPE) to (R)-phenyl-1,2-ethanediol ((R)-PED) of excellent enantiomeric excess (e.e. >99.9%). ...
Saccharomyces cerevisiae JUC15 was successfully obtained by target reaction-oriented screening, which reduced 2-hydroxy-1 …
2-Hydroxyacetophenone 4-phenylthiosemicarbazone.
Seena EB, Manoj E, Kurup MR. Seena EB, et al. Acta Crystallogr C. 2006 Aug;62(Pt 8):o486-8. doi: 10.1107/S0108270106014776. Epub 2006 Jul 22. Acta Crystallogr C. 2006. PMID: 16891727 No abstract available.
Facile synthesis of 2-hydroxyacetophenone from racemic styrene oxide catalyzed by engineered enzymes.
Söderlund I, Tjärnhage E, Hamnevik E, Widersten M. Söderlund I, et al. Biotechnol Lett. 2022 Aug;44(8):985-990. doi: 10.1007/s10529-022-03271-w. Epub 2022 Jun 22. Biotechnol Lett. 2022. PMID: 35731351 Free PMC article.
Racemic styrene oxide added to growth medium passively enters the cells and is hydrolyzed into (1R)-phenylethane-1,2-diol, which is subsequently oxidized to the acyloin 2-hydroxyacetophenone. Produced 2-hydroxyacetophenone escapes the cells via passive …
Racemic styrene oxide added to growth medium passively enters the cells and is hydrolyzed into (1R)-phenylethane-1,2-diol, which is subseque …
Efficient production of (S)-1-phenyl-1,2-ethanediol using xylan as co-substrate by a coupled multi-enzyme Escherichia coli system.
Rao J, Zhang R, Xu G, Li L, Xu Y. Rao J, et al. Microb Cell Fact. 2020 Apr 7;19(1):87. doi: 10.1186/s12934-020-01344-x. Microb Cell Fact. 2020. PMID: 32264866 Free PMC article.
(S)-carbonyl reductase II from Candida parapsilosis catalyzes the conversion of 2-hydroxyacetophenone to (S)-1-phenyl-1,2-ethanediol with NADPH as a cofactor. Glucose dehydrogenase with a Ala258Phe mutation is able to catalyze the oxidation of xylose with concomitan …
(S)-carbonyl reductase II from Candida parapsilosis catalyzes the conversion of 2-hydroxyacetophenone to (S)-1-phenyl-1,2-etha …
[Characterization of the affinity-tags-regulated (S)-carbonyl reductase 2 towards 2-hydroxyacetophenone reduction].
Li Y, Zhang R, Xu Y. Li Y, et al. Sheng Wu Gong Cheng Xue Bao. 2021 Dec 25;37(12):4277-4292. doi: 10.13345/j.cjb.210088. Sheng Wu Gong Cheng Xue Bao. 2021. PMID: 34984874 Free article. Chinese.
The (S)-carbonyl reductase 2 (SCR2) from Candida parapsilosis can reduce 2-hydroxyacetophenone, which is a valuable prochiral ketones. Different affinity tags, i.e. his-tag, strep-tag and MBP-tag, were attached to the N terminus of SCR2. These tagged SCR2 enzymes, i …
The (S)-carbonyl reductase 2 (SCR2) from Candida parapsilosis can reduce 2-hydroxyacetophenone, which is a valuable prochiral …
Calcium complexation by corticosteroids.
Hauser MR, Doxsee KM, Hope H. Hauser MR, et al. Inorg Chem. 2009 Nov 16;48(22):10780-8. doi: 10.1021/ic901670r. Inorg Chem. 2009. PMID: 19839577
Cortisone and hydrocortisone form calcium complexes of 2:1 steroid/Ca(2+) stoichiometry in solution, with formation constants of 201 +/- 1.7 and 184 +/- 1.7 M(-2), respectively-roughly half the value seen for a simple aromatic alpha-hydroxy ketone, phenacyl alcohol …
Cortisone and hydrocortisone form calcium complexes of 2:1 steroid/Ca(2+) stoichiometry in solution, with formation constants of 201 +/- 1.7 …
221 results