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Page 1
Conformation and bonding of 2-methoxypyridine and its monohydrate from rotational spectra.
Cheng W, Zheng Y, Feng G, Grabow JU, Gou Q. Cheng W, et al. Spectrochim Acta A Mol Biomol Spectrosc. 2020 Oct 5;239:118434. doi: 10.1016/j.saa.2020.118434. Epub 2020 May 6. Spectrochim Acta A Mol Biomol Spectrosc. 2020. PMID: 32438304
Rotational spectra of 2-methoxypyridine and its monohydrate have been characterized by pulsed jet Fourier transform microwave spectroscopy and complementary ab initio calculations. ...
Rotational spectra of 2-methoxypyridine and its monohydrate have been characterized by pulsed jet Fourier transform microwave …
The Synthesis, Characterization, Cytotoxic Activity Assessment and Structure-Activity Relationship of 4-Aryl-6-(2,5-dichlorothiophen-3-yl)-2-methoxypyridine-3-carbonitriles.
Al-Refai M, Ibrahim MM, Azmi MN, Osman H, Bakar MHA, Geyer A. Al-Refai M, et al. Molecules. 2019 Nov 10;24(22):4072. doi: 10.3390/molecules24224072. Molecules. 2019. PMID: 31717690 Free PMC article.
A series of 2-methoxypyridine-3-carbonitrile (5a-i)-bearing aryl substituents were successfully synthesized in good yields by the condensation of chalcones (4a-i) with malononitrile in basic medium. ...
A series of 2-methoxypyridine-3-carbonitrile (5a-i)-bearing aryl substituents were successfully synthesized in good yields by …
Conformational Equilibria of 2-Methoxypyridine CO(2) : Cooperative and Competitive Tetrel and Weak Hydrogen Bonds.
Cheng W, Zheng Y, Herbers S, Zheng H, Gou Q. Cheng W, et al. Chemphyschem. 2021 Jan 18;22(2):154-159. doi: 10.1002/cphc.202000910. Epub 2020 Dec 14. Chemphyschem. 2021. PMID: 33315294
The rotational spectrum of 2-methoxypyridine CO(2) was recorded and analysed employing a cavity-based Fourier transform microwave spectrometer, complemented with quantum chemical calculations which predicted three possible isomers within energies less than 1000 cm …
The rotational spectrum of 2-methoxypyridine CO(2) was recorded and analysed employing a cavity-based Fourier transform micr …
Conformational preferences and isomerization upon excitation/ionization of 2-methoxypyridine and 2-N-methylaminopyridine.
Dai W , Liu S , Zhang Z , Chi X , Cheng M , Du Y , Zhu Q . Dai W , et al. Phys Chem Chem Phys. 2018 Feb 28;20(9):6211-6226. doi: 10.1039/c7cp07854d. Phys Chem Chem Phys. 2018. PMID: 29431768
Conformers from the rotations of the methyl group and the methoxy or methylamino group, namely staggered (s)/eclipsed (e)-cis/trans 2-methoxypyridine (2MOP) and 2-N-methylaminopyridine (2NMP), are studied using theoretical calculations in combination with one-color …
Conformers from the rotations of the methyl group and the methoxy or methylamino group, namely staggered (s)/eclipsed (e)-cis/trans 2 …
Lithiation of 2-chloro- and 2-methoxypyridine with lithium dialkylamides: initial ortho-direction or subsequent lithium ortho-stabilization?
Gros P, Choppin S, Fort Y. Gros P, et al. J Org Chem. 2003 Mar 21;68(6):2243-7. doi: 10.1021/jo026559u. J Org Chem. 2003. PMID: 12636387
The lithiation pathway of 2-chloro and 2-methoxypyridine with LDA and LTMP has been investigated using deuterated probes. The availability of both H-6 and H-3 protons on the pyridine nucleus was found to be critical to ensure complete C-3 lithiation. ...
The lithiation pathway of 2-chloro and 2-methoxypyridine with LDA and LTMP has been investigated using deuterated probes. The …
2-Methoxypyridine as a Thymidine Mimic in Watson-Crick Base Pairs of DNA and PNA: Synthesis, Thermal Stability, and NMR Structural Studies.
Novosjolova I, Kennedy SD, Rozners E. Novosjolova I, et al. Chembiochem. 2017 Nov 2;18(21):2165-2170. doi: 10.1002/cbic.201700400. Epub 2017 Sep 26. Chembiochem. 2017. PMID: 28858428 Free PMC article.
The development of nucleic acid base-pair analogues that use new modes of molecular recognition is important both for fundamental research and practical applications. The goal of this study was to evaluate 2-methoxypyridine as a cationic thymidine mimic in the A-T b …
The development of nucleic acid base-pair analogues that use new modes of molecular recognition is important both for fundamental research a …
Acid-base equilibria in nonpolar media. 2.(1) Self-consistent basicity scale in THF solution ranging from 2-methoxypyridine to EtP(1)(pyrr) phosphazene.
Rodima T, Kaljurand I, Pihl A, Mäemets V, Leito I, Koppel IA. Rodima T, et al. J Org Chem. 2002 Mar 22;67(6):1873-81. doi: 10.1021/jo016185p. J Org Chem. 2002. PMID: 11895405
Based on the measurements, a basicity scale ranging from 2-methoxypyridine to EtP(1)(pyrr) and having a total span over 18 pK units has been created. ...
Based on the measurements, a basicity scale ranging from 2-methoxypyridine to EtP(1)(pyrr) and having a total span over 18 pK …
HIV-1 associated Topoisomerase IIβ kinase: a potential pharmacological target for viral replication.
Ponraj K, Prabhakar M, Rathore RS, Bommakanti A, Kondapi AK. Ponraj K, et al. Curr Pharm Des. 2013;19(26):4776-86. doi: 10.2174/1381612811319260008. Curr Pharm Des. 2013. PMID: 23260019 Review.
An in cell validation of the model with a representative inhibitor, 2-methoxypyridine shows its ability to inhibit Topo IIbeta phosphorylation during acute HIV-1 infection. ...
An in cell validation of the model with a representative inhibitor, 2-methoxypyridine shows its ability to inhibit Topo IIbeta …
36 results