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125 results

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Quoted phrase not found in phrase index: "a-propylpiperidine"
Page 1
Nicotinic plant poisoning.
Schep LJ, Slaughter RJ, Beasley DM. Schep LJ, et al. Clin Toxicol (Phila). 2009 Sep;47(8):771-81. doi: 10.1080/15563650903252186. Clin Toxicol (Phila). 2009. PMID: 19778187 Review.
They contain the toxic alkaloids nicotine, anabasine, cytisine, n-methylcytisine, coniine, n-methylconiine, and gamma-coniceine. MECHANISMS OF TOXICITY: These alkaloids act agonistically at nicotinic-type acetylcholine (cholinergic) receptors (nAChRs). ...
They contain the toxic alkaloids nicotine, anabasine, cytisine, n-methylcytisine, coniine, n-methylconiine, and gamma-coniceine. MECH …
The killer of Socrates: Coniine and Related Alkaloids in the Plant Kingdom.
Hotti H, Rischer H. Hotti H, et al. Molecules. 2017 Nov 14;22(11):1962. doi: 10.3390/molecules22111962. Molecules. 2017. PMID: 29135964 Free PMC article. Review.
Coniine's most famous victim is Socrates who was sentenced to death by poison chalice containing poison hemlock in 399 BC. ...Ultimately, reduction of gamma-coniceine to coniine is facilitated by NADPH-dependent gamma-coniceine reductase. Although coniine is …
Coniine's most famous victim is Socrates who was sentenced to death by poison chalice containing poison hemlock in 399 BC. ...Ultimat …
What kind of poison was used in "The Name of the Rose"?
Konopka T. Konopka T. Arch Med Sadowej Kryminol. 2020;70(4):191-201. doi: 10.5114/amsik.2020.104944. Arch Med Sadowej Kryminol. 2020. PMID: 34431644 Free article. Review. English.
Similar toxicity is displayed by water dropwort (Oenanthe crocata) and Cerbera odollam growing in India and Madagascar. Hemlock (Conium maculatum) contains coniine which is able to kill a victim after exposure to a dose as low as 100 to 200 mg. ...
Similar toxicity is displayed by water dropwort (Oenanthe crocata) and Cerbera odollam growing in India and Madagascar. Hemlock (Conium macu …
Poison hemlock determination in postmortem samples.
Labay LM, Chan-Hosokawa A, Homan JW, McMullin MM, Diamond FX, Annand MM, Marco SM, Hollenbach JM. Labay LM, et al. Forensic Sci Int. 2022 Dec;341:111500. doi: 10.1016/j.forsciint.2022.111500. Epub 2022 Oct 17. Forensic Sci Int. 2022. PMID: 36335848
Toxicological testing of the blood and gastric content by quantitative selected-ion monitoring Gas Chromatography/Mass Spectrometry (SIM-GC/MS) revealed the presence of coniine at concentrations of 410 ng/mL and 9300 ng/mL, respectively. The second case is from Pennsylvani …
Toxicological testing of the blood and gastric content by quantitative selected-ion monitoring Gas Chromatography/Mass Spectrometry (SIM-GC/ …
[Coniin, in Five Little Pigs].
Sakai KL. Sakai KL. Brain Nerve. 2023 Dec;75(12):1319-1323. doi: 10.11477/mf.1416202531. Brain Nerve. 2023. PMID: 38097221 Japanese.
In this manuscript, I provide some insights into the novel Five Little Pigs (US title: Murder in Retrospect) by Agatha Christie, and overview the neurotoxin coniine that plays an essential role in that story. Coniine is a nicotinic acetylcholine receptor antagonist, …
In this manuscript, I provide some insights into the novel Five Little Pigs (US title: Murder in Retrospect) by Agatha Christie, and overvie …
Antinociceptive activity of coniine in mice.
Arihan O, Boz M, Iskit AB, Ilhan M. Arihan O, et al. J Ethnopharmacol. 2009 Sep 7;125(2):274-8. doi: 10.1016/j.jep.2009.06.032. Epub 2009 Jul 4. J Ethnopharmacol. 2009. PMID: 19580858
RESULTS: Coniine caused a prolongation in reaction time in Hotplate test at 20mg/kg dose. In addition, it was observed that coniine decreased the number of writhes in Writhing test. ...It was also shown that antinociceptive effect of morphine was potentialized by …
RESULTS: Coniine caused a prolongation in reaction time in Hotplate test at 20mg/kg dose. In addition, it was observed that coniin …
[Rhabdomyolysis: have you considered food poisoning from quails?].
Basile C. Basile C. G Ital Nefrol. 2020 Apr 9;37(2):2020-vol2. G Ital Nefrol. 2020. PMID: 32281758 Review. Italian.
It follows the consumption of Coturnix coturnix, a species of quails common in Europe, that have ingested the toxic substances (and especially coniine) present in the herbaceous plant called hemlock (Conium maculatum). Coniine may be lethal at a dose of 150 mg but i …
It follows the consumption of Coturnix coturnix, a species of quails common in Europe, that have ingested the toxic substances (and especial …
Effect of coniine on the developing chick embryo.
Forsyth CS, Frank AA, Watrous BJ, Bohn AA. Forsyth CS, et al. Teratology. 1994 Apr;49(4):306-10. doi: 10.1002/tera.1420490410. Teratology. 1994. PMID: 8073369
Coniine, an alkaloid from Conium maculatum (poison hemlock), has been shown to be teratogenic in livestock. ...All concentrations of nicotine sulfate caused some lethality but a no effect level for coniine lethality was 0.75%. The deformations caused by both coni …
Coniine, an alkaloid from Conium maculatum (poison hemlock), has been shown to be teratogenic in livestock. ...All concentrations of …
The effect of coniine on presynaptic nicotinic receptors.
Erkent U, Iskit AB, Onur R, Ilhan M. Erkent U, et al. Z Naturforsch C J Biosci. 2016;71(5-6):115-20. doi: 10.1515/znc-2015-0194. Z Naturforsch C J Biosci. 2016. PMID: 27107833
There is limited knowledge about the role of presynaptic nicotinic receptors on the pharmacological and toxicological effects of coniine in the literature. The present study was undertaken to evaluate the possible role of presynaptic nicotinic receptors on the pharmacologi …
There is limited knowledge about the role of presynaptic nicotinic receptors on the pharmacological and toxicological effects of coniine …
Poison hemlock (Conium maculatum L.).
Vetter J. Vetter J. Food Chem Toxicol. 2004 Sep;42(9):1373-82. doi: 10.1016/j.fct.2004.04.009. Food Chem Toxicol. 2004. PMID: 15234067 Review.
It contains some piperidine alkaloids (coniine, N-methyl-coniine, conhydrine, pseudoconhydrine, gamma-coniceine), which are formed by the cyclisation of an eight-carbon chain derived from four acetate units. gamma-Coniceine is the precursor of the other hemlock alka …
It contains some piperidine alkaloids (coniine, N-methyl-coniine, conhydrine, pseudoconhydrine, gamma-coniceine), which are fo …
125 results