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733 results

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Quoted phrases not found in phrase index: "3,4,5-tribromophenylphenyl ether", "steoroids"
Page 1
Eribulin.
Perry CM. Perry CM. Drugs. 2011 Jul 9;71(10):1321-31. doi: 10.2165/11207520-000000000-00000. Drugs. 2011. PMID: 21770478 Review.
In in vitro studies, eribulin displayed antiproliferative activity against human breast cancer cell lines. Regression and elimination of breast tumours were observed in human tumour xenograft models. ...Peripheral neuropathy (incidence 5%) was the most common adverse event …
In in vitro studies, eribulin displayed antiproliferative activity against human breast cancer cell lines. Regression and elimination …
[Sevoflurane].
Gilsanz F, Celemín R, Blanc G, Orts MM. Gilsanz F, et al. Rev Esp Anestesiol Reanim. 1996 Aug-Sep;43(7):243-8. Rev Esp Anestesiol Reanim. 1996. PMID: 8966352 Review. Spanish.
Sevoflurane is the only ethereal anesthesia that does not trigger a reflex response or cause airway irritation during inhaled induction. ...Sevoflurane gives rise to hemodynamic stability, is not arrhythmogenic, and does not sensitize the myocardium to the effects of ca …
Sevoflurane is the only ethereal anesthesia that does not trigger a reflex response or cause airway irritation during inhaled inducti …
Pemafibrate inhibited renal dysfunction and fibrosis in a mouse model of adenine-induced chronic kidney disease.
Horinouchi Y, Murashima Y, Yamada Y, Yoshioka S, Fukushima K, Kure T, Sasaki N, Imanishi M, Fujino H, Tsuchiya K, Shinomiya K, Ikeda Y. Horinouchi Y, et al. Life Sci. 2023 May 15;321:121590. doi: 10.1016/j.lfs.2023.121590. Epub 2023 Mar 20. Life Sci. 2023. PMID: 36940907
Moreover, it inhibited the upregulation of monocyte chemoattractant protein-1, IL-1beta, tumor necrosis factor-alpha, and IL-6 in the kidneys of CKD mice. SIGNIFICANCE: These results demonstrated the renoprotective effects of pemafibrate in CKD mice, confirming its potenti …
Moreover, it inhibited the upregulation of monocyte chemoattractant protein-1, IL-1beta, tumor necrosis factor-alpha, and IL-6 in the …
(E)-2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol alleviates inflammatory responses in LPS-induced mice liver sepsis through inhibition of STAT3 phosphorylation.
Kim B, Yu JE, Yeo IJ, Son DJ, Lee HP, Roh YS, Lim KH, Yun J, Park H, Han SB, Hong JT. Kim B, et al. Int Immunopharmacol. 2023 Dec;125(Pt A):111124. doi: 10.1016/j.intimp.2023.111124. Epub 2023 Nov 6. Int Immunopharmacol. 2023. PMID: 37977740
We here used a mouse model to demonstrate that (E)-2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol (MMPP) treatment prevented the liver sepsis-related mortality induced by 30 mg/kg lipopolysaccharide (LPS) treatment and reduced LPS-induced increase in a …
We here used a mouse model to demonstrate that (E)-2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol (MMPP) treatme …
Multicenter phase II trial of Camrelizumab combined with Apatinib and Eribulin in heavily pretreated patients with advanced triple-negative breast cancer.
Liu J, Wang Y, Tian Z, Lin Y, Li H, Zhu Z, Liu Q, Su S, Zeng Y, Jia W, Yang Y, Xu S, Yao H, Jiang W, Song E. Liu J, et al. Nat Commun. 2022 May 31;13(1):3011. doi: 10.1038/s41467-022-30569-0. Nat Commun. 2022. PMID: 35641481 Free PMC article. Clinical Trial.
Tertiary lymphoid structure was associated with higher ORR. Patients with lower tumor PML or PLOD3 expression had favorable ORR and PFS. PD-L1 status was not associated with ORR/PFS. Grade 3/4 treatment-related adverse events occurred in 19 (41.3%) of 46 pati …
Tertiary lymphoid structure was associated with higher ORR. Patients with lower tumor PML or PLOD3 expression had favorable ORR and P …
Glycosylated antitumor ether lipids: activity and mechanism of action.
Arthur G, Bittman R. Arthur G, et al. Anticancer Agents Med Chem. 2014 May;14(4):592-606. doi: 10.2174/1871520614666140309231144. Anticancer Agents Med Chem. 2014. PMID: 24628233 Review.
Glycosylated antitumor ether lipids (GAELs) are distinguished from the alkyllysophospholipids or alkylphosphocholines classes of antitumor ether lipids (AEL) by the presence of a sugar moiety. ...The antitumor activities displayed by these experimental compounds aug …
Glycosylated antitumor ether lipids (GAELs) are distinguished from the alkyllysophospholipids or alkylphosphocholines classes of anti …
Synthesis and Anticancer and Antiviral Activities of C-2'-Branched Arabinonucleosides.
Bege M, Kiss A, Bereczki I, Hodek J, Polyák L, Szemán-Nagy G, Naesens L, Weber J, Borbás A. Bege M, et al. Int J Mol Sci. 2022 Oct 19;23(20):12566. doi: 10.3390/ijms232012566. Int J Mol Sci. 2022. PMID: 36293420 Free PMC article.
Three pyrimidine nucleosides containing C2'-butylsulfanylmethyl or -acetylthiomethyl groups showed promising cytotoxicity at low micromolar concentrations with good selectivity towards tumor cells. SAR analysis using a methyl beta-d-arabinofuranoside reference compound sho …
Three pyrimidine nucleosides containing C2'-butylsulfanylmethyl or -acetylthiomethyl groups showed promising cytotoxicity at low micromolar …
Brominated flame retardants effect in MCF-7 cells: Impact on vitamin D pathway.
Sousa S, Maia ML, Pestana D, Teixeira D, Ângelo-Dias M, Martins C, Borrego LM, Delerue-Matos C, Calhau C, Fernandes Domingues V, Faria A. Sousa S, et al. J Steroid Biochem Mol Biol. 2022 May;219:106079. doi: 10.1016/j.jsbmb.2022.106079. Epub 2022 Feb 7. J Steroid Biochem Mol Biol. 2022. PMID: 35143981
Brominated flame retardants (BFRs) are persistent environmental pollutants, allowing a constant human exposure which carries several health risks, including the occurrence of breast cancer and vitamin D deficiency. Vitamin D inhibits cell growth and is negatively associate …
Brominated flame retardants (BFRs) are persistent environmental pollutants, allowing a constant human exposure which carries several health …
Sevoflurane suppresses hepatocellular carcinoma cell progression via circ_0001649/miR-19a-3p/SGTB axis.
Sun N, Gong J, Zhang W, Yang X, Liu J. Sun N, et al. Histol Histopathol. 2023 May;38(5):537-547. doi: 10.14670/HH-18-484. Epub 2022 Jun 24. Histol Histopathol. 2023. PMID: 35747942
BACKGROUND: Sevoflurane is a widely used anesthetic agent and is reported to play an anti-tumor action in many cancers. However, the underlying mechanisms are largely unclear. ...HCC cell proliferation, migration, invasion, and apoptosis were assessed by 3-(4 …
BACKGROUND: Sevoflurane is a widely used anesthetic agent and is reported to play an anti-tumor action in many cancers. However, the …
Eribulin in metastatic breast cancer: Real world data.
Fernández-Laguna CL, Maray I, Macia-Rivas L, Álvarez-Asteinza C, Fernández-Lastras S, Velasco Durántez V, Carbajales Álvarez M, Lozano-Blázquez A. Fernández-Laguna CL, et al. Breast Dis. 2023;42(1):349-360. doi: 10.3233/BD-230031. Breast Dis. 2023. PMID: 38073367 Free article.
BACKGROUND: Metastatic breast cancer (MBC) is incurable. Systemic therapy is the standard treatment; however, an optimal sequence of chemotherapy has not been established. ...Comparison of median survival from this study versus published data were: progression-free-surviva …
BACKGROUND: Metastatic breast cancer (MBC) is incurable. Systemic therapy is the standard treatment; however, an optimal sequence of …
733 results