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733 results

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Quoted phrases not found in phrase index: "3,4,5-tribromophenylphenyl ether", "steoroids"
Page 1
Eribulin.
Perry CM. Perry CM. Drugs. 2011 Jul 9;71(10):1321-31. doi: 10.2165/11207520-000000000-00000. Drugs. 2011. PMID: 21770478 Review.
In in vitro studies, eribulin displayed antiproliferative activity against human breast cancer cell lines. Regression and elimination of breast tumours were observed in human tumour xenograft models. ...Peripheral neuropathy (incidence 5%) was the most common adverse event …
In in vitro studies, eribulin displayed antiproliferative activity against human breast cancer cell lines. Regression and elimination …
[Sevoflurane].
Gilsanz F, Celemín R, Blanc G, Orts MM. Gilsanz F, et al. Rev Esp Anestesiol Reanim. 1996 Aug-Sep;43(7):243-8. Rev Esp Anestesiol Reanim. 1996. PMID: 8966352 Review. Spanish.
Sevoflurane is the only ethereal anesthesia that does not trigger a reflex response or cause airway irritation during inhaled induction. ...Sevoflurane gives rise to hemodynamic stability, is not arrhythmogenic, and does not sensitize the myocardium to the effects of ca …
Sevoflurane is the only ethereal anesthesia that does not trigger a reflex response or cause airway irritation during inhaled inducti …
Pemafibrate inhibited renal dysfunction and fibrosis in a mouse model of adenine-induced chronic kidney disease.
Horinouchi Y, Murashima Y, Yamada Y, Yoshioka S, Fukushima K, Kure T, Sasaki N, Imanishi M, Fujino H, Tsuchiya K, Shinomiya K, Ikeda Y. Horinouchi Y, et al. Life Sci. 2023 May 15;321:121590. doi: 10.1016/j.lfs.2023.121590. Epub 2023 Mar 20. Life Sci. 2023. PMID: 36940907
Moreover, it inhibited the upregulation of monocyte chemoattractant protein-1, IL-1beta, tumor necrosis factor-alpha, and IL-6 in the kidneys of CKD mice. SIGNIFICANCE: These results demonstrated the renoprotective effects of pemafibrate in CKD mice, confirming its potenti …
Moreover, it inhibited the upregulation of monocyte chemoattractant protein-1, IL-1beta, tumor necrosis factor-alpha, and IL-6 in the …
Multicenter phase II trial of Camrelizumab combined with Apatinib and Eribulin in heavily pretreated patients with advanced triple-negative breast cancer.
Liu J, Wang Y, Tian Z, Lin Y, Li H, Zhu Z, Liu Q, Su S, Zeng Y, Jia W, Yang Y, Xu S, Yao H, Jiang W, Song E. Liu J, et al. Nat Commun. 2022 May 31;13(1):3011. doi: 10.1038/s41467-022-30569-0. Nat Commun. 2022. PMID: 35641481 Free PMC article. Clinical Trial.
Tertiary lymphoid structure was associated with higher ORR. Patients with lower tumor PML or PLOD3 expression had favorable ORR and PFS. PD-L1 status was not associated with ORR/PFS. Grade 3/4 treatment-related adverse events occurred in 19 (41.3%) of 46 pati …
Tertiary lymphoid structure was associated with higher ORR. Patients with lower tumor PML or PLOD3 expression had favorable ORR and P …
Glycosylated antitumor ether lipids: activity and mechanism of action.
Arthur G, Bittman R. Arthur G, et al. Anticancer Agents Med Chem. 2014 May;14(4):592-606. doi: 10.2174/1871520614666140309231144. Anticancer Agents Med Chem. 2014. PMID: 24628233 Review.
Glycosylated antitumor ether lipids (GAELs) are distinguished from the alkyllysophospholipids or alkylphosphocholines classes of antitumor ether lipids (AEL) by the presence of a sugar moiety. ...The antitumor activities displayed by these experimental compounds aug …
Glycosylated antitumor ether lipids (GAELs) are distinguished from the alkyllysophospholipids or alkylphosphocholines classes of anti …
(E)-2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol alleviates inflammatory responses in LPS-induced mice liver sepsis through inhibition of STAT3 phosphorylation.
Kim B, Yu JE, Yeo IJ, Son DJ, Lee HP, Roh YS, Lim KH, Yun J, Park H, Han SB, Hong JT. Kim B, et al. Int Immunopharmacol. 2023 Dec;125(Pt A):111124. doi: 10.1016/j.intimp.2023.111124. Epub 2023 Nov 6. Int Immunopharmacol. 2023. PMID: 37977740
We here used a mouse model to demonstrate that (E)-2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol (MMPP) treatment prevented the liver sepsis-related mortality induced by 30 mg/kg lipopolysaccharide (LPS) treatment and reduced LPS-induced increase in a …
We here used a mouse model to demonstrate that (E)-2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol (MMPP) treatme …
Eribulin in metastatic breast cancer: Real world data.
Fernández-Laguna CL, Maray I, Macia-Rivas L, Álvarez-Asteinza C, Fernández-Lastras S, Velasco Durántez V, Carbajales Álvarez M, Lozano-Blázquez A. Fernández-Laguna CL, et al. Breast Dis. 2023;42(1):349-360. doi: 10.3233/BD-230031. Breast Dis. 2023. PMID: 38073367 Free article.
BACKGROUND: Metastatic breast cancer (MBC) is incurable. Systemic therapy is the standard treatment; however, an optimal sequence of chemotherapy has not been established. ...Comparison of median survival from this study versus published data were: progression-free-surviva …
BACKGROUND: Metastatic breast cancer (MBC) is incurable. Systemic therapy is the standard treatment; however, an optimal sequence of …
A review of the genetic and related effects of 1,3-butadiene in rodents and humans.
Jackson MA, Stack HF, Rice JM, Waters MD. Jackson MA, et al. Mutat Res. 2000 Oct;463(3):181-213. doi: 10.1016/s1383-5742(00)00056-9. Mutat Res. 2000. PMID: 11018742 Review.
In this paper, the metabolism and genetic toxicity of 1,3-butadiene (BD) and its oxidative metabolites in humans and rodents is reviewed with attention to newer data that have been published since the latest evaluation of BD by the International Agency for Research on Cancer …
In this paper, the metabolism and genetic toxicity of 1,3-butadiene (BD) and its oxidative metabolites in humans and rodents is reviewed wit …
Eribulin: a novel cytotoxic chemotherapy agent.
Preston JN, Trivedi MV. Preston JN, et al. Ann Pharmacother. 2012 Jun;46(6):802-11. doi: 10.1345/aph.1Q636. Epub 2012 May 22. Ann Pharmacother. 2012. PMID: 22619477 Review.
Eribulin has also shown activity in Phase 2 studies in other types of cancers, such as non-small cell lung cancer, prostate cancer, urothelial cancer, soft tissue sarcomas, and platinum-susceptible ovarian, fallopian tube, or peritoneal cancers. The most seve …
Eribulin has also shown activity in Phase 2 studies in other types of cancers, such as non-small cell lung cancer, prostate cancer …
Lipid-lowering agent-triggered dermatomyositis and polymyositis: a case series and literature review.
Borges IBP, Silva MG, Misse RG, Shinjo SK. Borges IBP, et al. Rheumatol Int. 2018 Feb;38(2):293-301. doi: 10.1007/s00296-017-3821-3. Epub 2017 Oct 12. Rheumatol Int. 2018. PMID: 29027009 Review.
Seven patients had previously taken simvastatin 20 mg/day (exposure period from 2 days to 4 years) and two bezafibrate 100 mg/day (3-4 months). Median time from symptom onset to disease diagnosis was 6 months. All patients with DM had a heliotrope and/or Gottron's p …
Seven patients had previously taken simvastatin 20 mg/day (exposure period from 2 days to 4 years) and two bezafibrate 100 mg/day (3- …
733 results