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Table representation of search results timeline featuring number of search results per year.
| Year | Number of Results |
|---|---|
| 1968 | 2 |
| 1969 | 7 |
| 1970 | 5 |
| 1971 | 10 |
| 1972 | 7 |
| 1973 | 10 |
| 1974 | 11 |
| 1975 | 17 |
| 1976 | 14 |
| 1977 | 18 |
| 1978 | 14 |
| 1979 | 4 |
| 1980 | 14 |
| 1981 | 11 |
| 1982 | 10 |
| 1983 | 5 |
| 1984 | 9 |
| 1985 | 8 |
| 1986 | 2 |
| 1987 | 5 |
| 1988 | 6 |
| 1989 | 2 |
| 1990 | 3 |
| 1991 | 3 |
| 1993 | 1 |
| 1994 | 1 |
| 1995 | 1 |
| 1996 | 1 |
| 1997 | 1 |
| 1998 | 3 |
| 1999 | 1 |
| 2003 | 1 |
| 2004 | 2 |
| 2005 | 1 |
| 2009 | 1 |
| 2010 | 1 |
| 2011 | 1 |
| 2012 | 1 |
| 2019 | 1 |
| 2020 | 1 |
| 2022 | 1 |
| 2025 | 1 |
Search Results
216 results
Results by year
Page 1
Clinical pharmacokinetics of vasodilators. Part II.
Clin Pharmacokinet. 1998 Jul;35(1):9-36. doi: 10.2165/00003088-199835010-00002.
Clin Pharmacokinet. 1998.
PMID: 9673832
Review.
Stimulating cardiac beta 1-adrenoceptors with oxyfedrine causes dilatation of coronary vessels and positive inotropic effects on the myocardium. beta 1-adrenergic agonists increase coronary blood flow in nonstenotic and stenotic vessels. ...
Stimulating cardiac beta 1-adrenoceptors with oxyfedrine causes dilatation of coronary vessels and positive inotropic effects on the …
Effects of oxyfedrine on isolated portal vein and other smooth muscles.
Br J Pharmacol. 1973 Apr;47(4):827-37. doi: 10.1111/j.1476-5381.1973.tb08210.x.
Br J Pharmacol. 1973.
PMID: 4146743
Free PMC article.
In the same concentrations, oxyfedrine reduced or prevented the inhibition of myogenic activity of the rat portal vein induced by isoprenaline and by repeated doses of oxyfedrine itself, acting as a partial agonist at beta-adrenoceptor sites.3. ...Oxyfedrine …
In the same concentrations, oxyfedrine reduced or prevented the inhibition of myogenic activity of the rat portal vein induced by iso …
Recent progress in the chemistry of β-aminoketones.
RSC Adv. 2022 Aug 31;12(38):24681-24712. doi: 10.1039/d2ra03864a. eCollection 2022 Aug 30.
RSC Adv. 2022.
PMID: 36128366
Free PMC article.
Review.
The beta-aminoketone moiety has been found to be the basic skeleton of several drugs such as the amine salts "tolperisone (vasodilation)" and "oxyfedrine (therapeutic coronary disease)", and fluoroaryl derivatives such as "sitagliptin (antidiabetic)". ...
The beta-aminoketone moiety has been found to be the basic skeleton of several drugs such as the amine salts "tolperisone (vasodilation)" an …
Oxyfederine and propranolol--a controlled trial in angina pectoris.
Br J Clin Pharmacol. 1980 Nov;10(5):439-42. doi: 10.1111/j.1365-2125.1980.tb01785.x.
Br J Clin Pharmacol. 1980.
PMID: 7437255
Free PMC article.
Clinical Trial.
1 A double-blind-crossover randomised trial was performed to compare the effects of oxyfedrine (maximum dose 32 mg three times daily), propranolol (maximum dose 120 mg three times daily) and placebo in 30 patients with chronic stable angina pectoris. Assessment was by mean …
1 A double-blind-crossover randomised trial was performed to compare the effects of oxyfedrine (maximum dose 32 mg three times daily) …
Effects of oxyfedrine on regional myocardial blood flow in patients with coronary artery disease.
Cardiovasc Drugs Ther. 1991 Dec;5(6):991-6. doi: 10.1007/BF00143526.
Cardiovasc Drugs Ther. 1991.
PMID: 1801897
We assessed the effects of intravenous oxyfedrine on regional myocardial blood flow, using positron emission tomography (15-oxygen water), in six patients with chronic stable angina, positive exercise tests, and documented coronary artery disease. Myocardial blood flow was …
We assessed the effects of intravenous oxyfedrine on regional myocardial blood flow, using positron emission tomography (15-oxygen wa …
Effect of intravenous oxyfedrine on exercise in patients with ischaemic heart disease.
Indian Heart J. 1991 Jan-Feb;43(1):21-4.
Indian Heart J. 1991.
PMID: 1894296
Clinical Trial.
Time to one mm ST segment depression was increased with oxyfedrine as compared to placebo (1.5 +/- 1.5 to 1.9 +/- 1.5 minutes, p less than 0.05). ...It is concluded that intravenous oxyfedrine improves exercise capacity in patients with stable effort angina presumab …
Time to one mm ST segment depression was increased with oxyfedrine as compared to placebo (1.5 +/- 1.5 to 1.9 +/- 1.5 minutes, p less …
Vasodilator oxyfedrine inhibits aldehyde metabolism and thereby sensitizes cancer cells to xCT-targeted therapy.
Cancer Sci. 2020 Jan;111(1):127-136. doi: 10.1111/cas.14224. Epub 2019 Nov 22.
Cancer Sci. 2020.
PMID: 31692172
Free PMC article.
We have now identified the vasodilator oxyfedrine (OXY) as a sensitizer of cancer cells to GSH-depleting agents including the xCT inhibitor sulfasalazine (SSZ). Oxyfedrine contains a structural motif required for covalent inhibition of aldehyde dehydrogenase (ALDH) …
We have now identified the vasodilator oxyfedrine (OXY) as a sensitizer of cancer cells to GSH-depleting agents including the xCT inh …
Physiological changes induced by chromium stress in plants: an overview.
Protoplasma. 2012 Jul;249(3):599-611. doi: 10.1007/s00709-011-0331-0. Epub 2011 Oct 16.
Protoplasma. 2012.
PMID: 22002742
Review.
The haemodynamic effects of prolonged oral administration of oxyfedrine, a partial agonist at beta-adrenoceptors: comparison with propranolol.
Br J Pharmacol. 1974 May;51(1):5-13. doi: 10.1111/j.1476-5381.1974.tb09625.x.
Br J Pharmacol. 1974.
PMID: 4155336
Free PMC article.
The degree of shift was five-fold (positive chronotropic response) and 20-fold (decrease in diastolic blood pressure) in the oxyfedrine group and 10- and 80-fold, respectively, in the propranolol group.4 In contrast to the partial blockade of the effects of isoprenaline, t …
The degree of shift was five-fold (positive chronotropic response) and 20-fold (decrease in diastolic blood pressure) in the oxyfedrine …
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