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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1998 19
1999 67
2000 49
2001 50
2002 46
2003 56
2004 59
2005 60
2006 73
2007 49
2008 53
2009 49
2010 69
2011 70
2012 75
2013 87
2014 83
2015 101
2016 90
2017 93
2018 84
2019 75
2020 1
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1,295 results
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Page 1
Simultaneous determination of D-lactic acid and 3-hydroxybutyric acid in rat plasma using a column-switching HPLC with fluorescent derivatization with 4-nitro-7-piperazino-2,1,3-benzoxadiazole (NBD-PZ).
Fukushima T, et al. Biomed Chromatogr 2001. PMID 11391675
A highly sensitive method for the determination of D-lactic acid and 3-hydroxybutyric acid (3-HB) in rat plasma was developed using high-performance liquid chromatography with octadecylsilica (ODS) connected to a chiral column. ...The detection limits for D-lactic acid and 3-HB were approximately 2.0 and 0.04 microM, respectively (signal-to-noise ratio 3). ...
A highly sensitive method for the determination of D-lactic acid and 3-hydroxybutyric acid (3-HB) in rat …
HPLC determination of D-3-hydroxybutyric acid by derivatization with a benzofurazan reagent and fluorescent detection: application in the analysis of human plasma.
Cevasco G, et al. Clin Chim Acta 2014. PMID 24315779
A simple and sensitive new method for the determination of D-3-hydroxybutyric acid (D-3-HBA) in human plasma after derivatization is described. ...The HPLC analysis was carried out by use of a C18 analytical column (Synergy Hydro 150 mm × 3 mm, i.d., 4 μm) with a binary gradient elution program of 0.1% aqueous trifluoroacetic acid versus methanol. ...
A simple and sensitive new method for the determination of D-3-hydroxybutyric acid (D-3-HBA) in human plasma aft …
Enzymatic-HPLC method to analyze D-3-hydroxybutyric acid in rat serum.
Ide T. Biosci Biotechnol Biochem 2010. PMID 20699574 Free article.
Standard samples containing varying amounts of D-3-hydroxybutyric acid (0-10 nmol in 50 microl) were treated with 3-hydroxybutyrate dehydrogenase and analyzed by HPLC (the injected amount was 0-2.7 nmol of D-3-hydroxybutuyric acid), resulting in the peak area increasing proportionally with the injected amount. The method proved sensitive enough for as little as 0.2-2 nmol D-3-hydroxybutyric acid in 50 microl to be accurately analyzed. ...
Standard samples containing varying amounts of D-3-hydroxybutyric acid (0-10 nmol in 50 microl) were treated with 3
A new way to produce hyperketonemia: use of ketone ester in a case of Alzheimer's disease
Newport MT, et al. Alzheimers Dement 2015. PMID 25301680 Free PMC article.
Cognitive performance tracked plasma β-hydroxybutyrate concentrations, with noticeable improvements in conversation and interaction at the higher levels, compared with predose levels. ...
Cognitive performance tracked plasma β-hydroxybutyrate concentrations, with noticeable improvements in conversation and interaction a …
An 8-Week Ketogenic Diet Alternated Interleukin-6, Ketolytic and Lipolytic Gene Expression, and Enhanced Exercise Capacity in Mice
Ma S, et al. Nutrients 2018. PMID 30405021 Free PMC article.
Adjusting dietary fat intake is reported to affect mitochondrial biogenesis and fatty acid oxidation (FAO), and thus may enhance exercise capacity. ...In the present study, we investigated how an eight-week KD alters mRNA expression during fatty acid mobilization, FAO and ketolysis. ...
Adjusting dietary fat intake is reported to affect mitochondrial biogenesis and fatty acid oxidation (FAO), and thus may enhance exer …
Glucose intolerance in dairy goats with pregnancy toxemia: Lack of correlation between blood pH and beta hydroxybutyric acid values.
Lima MS, et al. Can Vet J 2016. PMID 27247464 Free PMC article.
Blood glucose concentrations returned to pre-infusion levels by 90 min in all 8 HL goats, and by 180 min in all 8 HP goats. In contrast, concentrations of blood glucose were still significantly above pre-infusion levels at 180 min post-infusion in all 8 PT goats. ...In 25 goats diagnosed with PT and having blood beta hydroxybutyric acid (BHBA) values ≥ 2.9 mmol/L, the correlation coefficient for BHBA with blood pH was non-significant....
Blood glucose concentrations returned to pre-infusion levels by 90 min in all 8 HL goats, and by 180 min in all 8 HP goats. In contra
Effect of a ketogenic meal on cognitive function in elderly adults: potential for cognitive enhancement
Ota M, et al. Psychopharmacology (Berl) 2016. PMID 27568199
As for cognition, improvements were observed in the digit span test, Trail-Making Test B, and the global score (Z = -2.4, p = 0.017) following the ketogenic meal and the change in the executive functioning score was positively correlated with that of the plasma β-hydroxybutyrate level. ...
As for cognition, improvements were observed in the digit span test, Trail-Making Test B, and the global score (Z = -2.4, p = 0.017) followi …
Exclusive breast-feeding and postnatal changes in blood sodium, ketone, and glucose levels.
Futatani T, et al. Pediatr Int 2019. PMID 30854754
METHODS: Capillary blood sodium, β-hydroxybutyrate (β-OHB), and glucose levels in 628 samples obtained from 392 healthy, term, exclusively breast-fed neonates during the first 12-143 h of life were examined. RESULTS: Blood sodium and β-OHB gradually increased and reached a peak at 48-59 h of life (mean blood sodium, 142.3 ± 2.8 mEq/L; mean blood sodium increase, 3.3 mEq/L; mean β-OHB, 1.16 ± 0.46 mmol/L; mean β-OHB increase, 0.65 mmol/L), and then gradually decreased and reached a nadir at 120-143 h of life. ...
METHODS: Capillary blood sodium, β-hydroxybutyrate (β-OHB), and glucose levels in 628 samples obtained from 392 healthy, term, …
Review: Inhibition of prolactin as a management tool in dairy husbandry
Lacasse P, et al. Animal 2019 - Review. PMID 31280741
Blood glucose and calcium concentrations were higher and β-hydroxybutyric acid concentration was lower in the quinagolide-treated cows. ...The quinagolide-treated cows had higher glucose and lower β-hydroxybutyric acid and non-esterified fatty acid concentrations than the control cows did. ...
Blood glucose and calcium concentrations were higher and β-hydroxybutyric acid concentration was lower in the quinagoli
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