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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1960 6
1961 9
1962 9
1963 35
1964 27
1965 25
1966 20
1967 40
1968 53
1969 45
1970 33
1971 22
1972 22
1973 24
1974 27
1975 29
1976 27
1977 19
1978 13
1979 23
1980 15
1981 9
1982 23
1983 25
1984 12
1985 16
1986 15
1987 16
1988 17
1989 10
1990 15
1991 5
1992 9
1993 8
1994 4
1995 2
1996 5
1997 1
1998 1
1999 1
2000 5
2001 1
2002 4
2003 2
2004 4
2005 3
2006 2
2009 1
2010 1
2012 1
2013 1
2014 1
2016 1
2017 1
2018 1
2021 1
2022 2
2023 1
2024 0

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746 results

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Quoted phrases not found in phrase index: "3-methylbut-2-en-1-amine", "N-(3,3-diphenylpropyl)-a-methylphenylethylamine"
Page 1
Analytical developments of p-hydroxy prenylamine reference material for dope control research: Characterization and purity assessment.
Joseph A, Kumar GJ, Pawar SD, Hirlekar BU, Bharatam PV, Konda S, Mudiam MKR, Murty US, Sahu PL, Dubey S, Radhakrishnanand P, Adye DR, Borkar RM, Thirupathi C, Kumar P. Joseph A, et al. Drug Test Anal. 2022 Feb;14(2):224-232. doi: 10.1002/dta.3171. Epub 2021 Oct 26. Drug Test Anal. 2022. PMID: 34617411
The major phase I metabolite of prenylamine is p-hydroxy prenylamine that has a chiral center in the structure. ...A normal phase chiral HPLC method was developed to analyze the p-hydroxy prenylamine purity. Separation of the p-hydroxy prenylamine enan …
The major phase I metabolite of prenylamine is p-hydroxy prenylamine that has a chiral center in the structure. ...A normal ph …
Local anesthetic properties of prenylamine.
Mujtaba MG, Gerner P, Wang GK. Mujtaba MG, et al. Anesthesiology. 2001 Nov;95(5):1198-204. doi: 10.1097/00000542-200111000-00025. Anesthesiology. 2001. PMID: 11684990 Free article.
RESULTS: Prenylamine elicits both use-dependent block of Na(+) channels during repetitive pulses (3 microm prenylamine produced 50% block at 5 Hz) and tonic block for both resting and inactivated Na(+) channels. The 50% inhibitory concentration for prenylamine
RESULTS: Prenylamine elicits both use-dependent block of Na(+) channels during repetitive pulses (3 microm prenylamine produce …
Basic mechanisms underlying prenylamine-induced 'torsade de pointes': differences between prenylamine and fendiline due to basic actions of the isomers.
Bayer R, Schwarzmaier J, Pernice R. Bayer R, et al. Curr Med Res Opin. 1988;11(4):254-72. doi: 10.1185/03007998809114244. Curr Med Res Opin. 1988. PMID: 3063437 Review.
The calcium antagonists prenylamine and fendiline both bind with rather low affinity to the dihydropyridine (nifedipine) binding site. ...These effects are postulated to represent the main mechanisms triggering torsade de pointes during therapy with prenylamine. Tho …
The calcium antagonists prenylamine and fendiline both bind with rather low affinity to the dihydropyridine (nifedipine) binding site …
The role of prenylamine in the prevention of adriamycin-induced cardiotoxicity. A review of experimental and clinical findings.
Milei J, Vazquez A, Boveris A, Llesuy S, Molina HA, Storino R, Marantz A. Milei J, et al. J Int Med Res. 1988 Jan-Feb;16(1):19-30. doi: 10.1177/030006058801600102. J Int Med Res. 1988. PMID: 3280362 Review.
Experimental and clinical trials to determine the potential of prenylamine in the prevention of adriamycin-related cardiotoxicity are reviewed. ...Adriamycin-induced electrocardiogram changes were observed to a lesser extent in animals also receiving prenylamine. He …
Experimental and clinical trials to determine the potential of prenylamine in the prevention of adriamycin-related cardiotoxicity are …
HIGH-ALTITUDE PULMONARY HYPERTENSION.
SINGH I, KHANNA PK, LAL M, HOON RS, RAO BD. SINGH I, et al. Lancet. 1965 Jul 24;2(7404):146-50. doi: 10.1016/s0140-6736(65)90229-1. Lancet. 1965. PMID: 14330043 No abstract available.
Adverse reactions to calcium antagonists.
Lewis JG. Lewis JG. Drugs. 1983 Feb;25(2):196-222. doi: 10.2165/00003495-198325020-00006. Drugs. 1983. PMID: 6339200 Review. No abstract available.
Withdrawal of prenylamine: perspectives on pharmacological, clinical and regulatory outcomes following the first QT-related casualty.
Shah RR, Stonier PD. Shah RR, et al. Ther Adv Drug Saf. 2018 Jun 18;9(8):475-493. doi: 10.1177/2042098618780854. eCollection 2018 Aug. Ther Adv Drug Saf. 2018. PMID: 30364900 Free PMC article. Review.
Prenylamine, an antianginal agent marketed since early 1960, became the first casualty of QT interval related proarrhythmias in 1988 when it was withdrawn from the market. ...Application of these guidelines would have readily identified its proarrhythmic potential. Pren
Prenylamine, an antianginal agent marketed since early 1960, became the first casualty of QT interval related proarrhythmias in 1988
746 results