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514 results

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Page 1
The pyrethroids metabolite 3-phenoxybenzoic acid induces dopaminergic degeneration.
Wan F, Yu T, Hu J, Yin S, Li Y, Kou L, Chi X, Wu J, Sun Y, Zhou Q, Zou W, Zhang Z, Wang T. Wan F, et al. Sci Total Environ. 2022 Sep 10;838(Pt 2):156027. doi: 10.1016/j.scitotenv.2022.156027. Epub 2022 May 20. Sci Total Environ. 2022. PMID: 35605864
To find the shared key features among these mechanisms, we focused on 3-phenoxybenzoic acid (3-PBA), a common and prominent metabolite of most pyrethroids produced via hydrolysis by CEs in mammals. ...
To find the shared key features among these mechanisms, we focused on 3-phenoxybenzoic acid (3-PBA), a common an …
Co-metabolic enzymes and pathways of 3-phenoxybenzoic acid degradation by Aspergillus oryzae M-4.
Zhao J, Jia D, Chi Y, Yao K. Zhao J, et al. Ecotoxicol Environ Saf. 2020 Feb;189:109953. doi: 10.1016/j.ecoenv.2019.109953. Epub 2019 Nov 20. Ecotoxicol Environ Saf. 2020. PMID: 31759741
As an intermediate metabolite of pyrethroids, 3-phenoxybenzoic acid (3-PBA) is more toxic than its parent compounds and has been detected in milk, soil, and human urine. 3-PBA can be metabolized through microbial degradation, but the microbial co-metab …
As an intermediate metabolite of pyrethroids, 3-phenoxybenzoic acid (3-PBA) is more toxic than its parent compou …
3-Phenoxybenzoic Acid Induces Neuronal Pentraxin 2 to Upregulate Complement Activity and Promotes Microglia-Mediated Neuronal Synaptic Damage.
Hu G, Wang K, Wu C, Liu Q, Zhang Q, Qi A, Huang M. Hu G, et al. J Mol Neurosci. 2025 Jun 26;75(3):83. doi: 10.1007/s12031-025-02374-z. J Mol Neurosci. 2025. PMID: 40571817
3-Phenoxybenzoic acid (3-PBA) has been demonstrated to be associated with neurrotoxicity, however, the precise mechanism through which it exerts its neurotoxic effects remains to be fully elucidated. ...
3-Phenoxybenzoic acid (3-PBA) has been demonstrated to be associated with neurrotoxicity, however, the precise m
Association of 3-Phenoxybenzoic Acid Exposure during Pregnancy with Maternal Outcomes and Newborn Anthropometric Measures: Results from the IoMum Cohort Study.
Guimarães J, Bracchi I, Pinheiro C, Moreira NX, Coelho CM, Pestana D, Prucha MDC, Martins C, Domingues VF, Delerue-Matos C, Dias CC, Azevedo LFR, Calhau C, Leite JC, Ramalho C, Keating E, Fernandes VC. Guimarães J, et al. Toxics. 2023 Jan 27;11(2):125. doi: 10.3390/toxics11020125. Toxics. 2023. PMID: 36851000 Free PMC article.
The aims of this study were to characterize the exposure of pregnant women living in Portugal to 3-phenoxybenzoic acid (3-PBA) and to evaluate the association of this exposure with maternal outcomes and newborn anthropometric measures. ...
The aims of this study were to characterize the exposure of pregnant women living in Portugal to 3-phenoxybenzoic acid
Urinary 3-phenoxybenzoic acid (3-PBA) levels and changes in hematological parameters in Korean adult population: A Korean National Environmental Health Survey (KoNEHS) 2012-2014 analysis.
Choi YH, Lee JY, Huh DA, Moon KW. Choi YH, et al. Int J Hyg Environ Health. 2022 Jun;243:113988. doi: 10.1016/j.ijheh.2022.113988. Epub 2022 May 28. Int J Hyg Environ Health. 2022. PMID: 35640467
This study aimed to investigate the effect of urinary 3-phenoxybenzoic acid (3-PBA) concentrations on hematological parameters in a representative South Korean adult population. ...
This study aimed to investigate the effect of urinary 3-phenoxybenzoic acid (3-PBA) concentrations on hematologi …
Degradation of 3-phenoxybenzoic acid by a Bacillus sp.
Chen S, Hu W, Xiao Y, Deng Y, Jia J, Hu M. Chen S, et al. PLoS One. 2012;7(11):e50456. doi: 10.1371/journal.pone.0050456. Epub 2012 Nov 30. PLoS One. 2012. PMID: 23226289 Free PMC article.
3-Phenoxybenzoic acid (3-PBA) is of great environmental concern with regards to endocrine disrupting activity and widespread occurrence in water and soil, yet little is known about microbial degradation in contaminated regions. ...
3-Phenoxybenzoic acid (3-PBA) is of great environmental concern with regards to endocrine disrupting activity an
Urinary 3-phenoxybenzoic acid (3-PBA) concentration and pulmonary function in children: A National Health and Nutrition Examination Survey (NHANES) 2007-2012 analysis.
Hu P, Su W, Vinturache A, Gu H, Cai C, Lu M, Ding G. Hu P, et al. Environ Pollut. 2021 Feb 1;270:116178. doi: 10.1016/j.envpol.2020.116178. Epub 2020 Dec 13. Environ Pollut. 2021. PMID: 33341554
Epidemiological studies have reported association of urinary 3-phenoxybenzoic acid (3-PBA), a major metabolite of pyrethroid insecticides (PYRs), with respiratory disease. ...
Epidemiological studies have reported association of urinary 3-phenoxybenzoic acid (3-PBA), a major metabolite o …
Transcriptomic analysis reveals peripheral pathway in 3-phenoxybenzoic acid degradation by Aspergillus oryzae M-4.
Hu K, Li J, Zhao T, Zhou Q, Li Q, Hu X, Han G, Li S, Zou L, Liu S. Hu K, et al. J Environ Manage. 2023 Jan 1;325(Pt B):116626. doi: 10.1016/j.jenvman.2022.116626. Epub 2022 Oct 31. J Environ Manage. 2023. PMID: 36327606
As a major intermediate metabolite of synthetic pyrethroids, the occurrence of 3-phenoxybenzoic acid hinders the decomposition of the parent pesticide and poses uncertain risks to environmental ecology and living organisms. ...
As a major intermediate metabolite of synthetic pyrethroids, the occurrence of 3-phenoxybenzoic acid hinders the decomp …
Urinary 3-phenoxybenzoic acid levels and the association with thyroid hormones in adults: Korean National Environmental Health Survey 2012-2014.
Hwang M, Lee Y, Choi K, Park C. Hwang M, et al. Sci Total Environ. 2019 Dec 15;696:133920. doi: 10.1016/j.scitotenv.2019.133920. Epub 2019 Aug 14. Sci Total Environ. 2019. PMID: 31446285
However, the thyroid disrupting effects of pyrethroids, particularly in humans, is relatively underexplored. OBJECTIVES: This study aimed to report 3-phenoxybenzoic acid (3-PBA) concentrations in urine, and assess its association with serum thyroid hor …
However, the thyroid disrupting effects of pyrethroids, particularly in humans, is relatively underexplored. OBJECTIVES: This study aimed to …
514 results