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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 1
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1982 1
1983 1
1984 4
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1987 1
1988 2
1989 2
1990 1
1991 2
1992 3
1993 4
1994 3
1995 3
1996 2
1997 2
1998 5
1999 3
2000 6
2001 8
2002 3
2003 9
2004 10
2005 11
2006 18
2007 17
2008 18
2009 23
2010 12
2011 21
2012 15
2013 21
2014 14
2015 18
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2019 24
2020 23
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2022 12
2023 20
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2026 15

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397 results

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Page 1
A gut-derived metabolite alters brain activity and anxiety behaviour in mice.
Needham BD, Funabashi M, Adame MD, Wang Z, Boktor JC, Haney J, Wu WL, Rabut C, Ladinsky MS, Hwang SJ, Guo Y, Zhu Q, Griffiths JA, Knight R, Bjorkman PJ, Shapiro MG, Geschwind DH, Holschneider DP, Fischbach MA, Mazmanian SK. Needham BD, et al. Nature. 2022 Feb;602(7898):647-653. doi: 10.1038/s41586-022-04396-8. Epub 2022 Feb 14. Nature. 2022. PMID: 35165440 Free PMC article.
Here we identified biosynthetic genes from the gut microbiome that mediate the conversion of dietary tyrosine to 4-ethylphenol (4EP), and bioengineered gut bacteria to selectively produce 4EPS in mice. 4EPS entered the brain and was associated with changes in region …
Here we identified biosynthetic genes from the gut microbiome that mediate the conversion of dietary tyrosine to 4-ethylphenol …
4-Ethylphenol-fluxes, metabolism and excretion of a gut microbiome derived neuromodulator implicated in autism.
Day F, O'Sullivan J, Pook C. Day F, et al. Front Mol Biosci. 2023 Oct 12;10:1267754. doi: 10.3389/fmolb.2023.1267754. eCollection 2023. Front Mol Biosci. 2023. PMID: 37900921 Free PMC article. Review.
Gut-microbiome-derived metabolites, such as 4-Ethylphenol [4EP], have been shown to modulate neurological health and function. Although the source of such metabolites is becoming better understood, knowledge gaps remain as to the mechanisms by which they enter host …
Gut-microbiome-derived metabolites, such as 4-Ethylphenol [4EP], have been shown to modulate neurological health and function. …
4-Ethylphenol metabolism by Aspergillus fumigatus.
Jones KH, Trudgill PW, Hopper DJ. Jones KH, et al. Appl Environ Microbiol. 1994 Jun;60(6):1978-83. doi: 10.1128/aem.60.6.1978-1983.1994. Appl Environ Microbiol. 1994. PMID: 8031091 Free PMC article.
The initial step involves hydroxylation of the methylene group of 4-ethylphenol to form 1-(4'-hydroxyphenyl)ethanol, followed by oxidation to 4-hydroxyacetophenone. ...Cells grown on 4-ethylphenol were able to oxidize all of these compounds immediately …
The initial step involves hydroxylation of the methylene group of 4-ethylphenol to form 1-(4'-hydroxyphenyl)ethanol, followed …
Stereochemical aspects of the oxidation of 4-ethylphenol by the bacterial enzyme 4-ethylphenol methylenehydroxylase.
Reeve CD, Carver MA, Hopper DJ. Reeve CD, et al. Biochem J. 1990 Aug 1;269(3):815-9. doi: 10.1042/bj2690815. Biochem J. 1990. PMID: 1697166 Free PMC article.
The O2-independent hydroxylase 4-ethylphenol methylenehydroxylase (4EPMH) from Pseudomonas putida JD1 catalysed the complete conversion of 4-ethylphenol into 1-(4-hydroxyphenyl)ethanol together with a small amount of 4-hydroxyacetophenone, but with no …
The O2-independent hydroxylase 4-ethylphenol methylenehydroxylase (4EPMH) from Pseudomonas putida JD1 catalysed the complete c …
The Catabolic Network of Aromatoleum aromaticum EbN1T.
Becker P, Wünsch D, Wöhlbrand L, Neumann-Schaal M, Schomburg D, Rabus R. Becker P, et al. Microb Physiol. 2024;34(1):1-77. doi: 10.1159/000534425. Epub 2023 Oct 10. Microb Physiol. 2024. PMID: 37816339 Free article. Review.
Its degradation section is composed of 31 peripheral and 4 central pathways, with several peripheral modules (e.g., for 4-ethylphenol, 2-phenylethylamine, indoleacetate, and phenylpropanoids) discovered only after the complete genome [Arch Microbiol. 2005 Jan;183(1) …
Its degradation section is composed of 31 peripheral and 4 central pathways, with several peripheral modules (e.g., for 4-ethylphe …
Simultaneous determination of 4-ethylphenol and 4-ethylguaicol on C(60) modified dual screen-printed electrochemical sensors.
Portugal-Gómez P, Alonso-Lomillo MA, Domínguez-Renedo O. Portugal-Gómez P, et al. Talanta. 2024 Apr 1;270:125543. doi: 10.1016/j.talanta.2023.125543. Epub 2023 Dec 13. Talanta. 2024. PMID: 38103285 Free article.
4-ethylphenol and 4-ethylguaicol levels in wine are associated to organoleptic defects that cause consumer rejection accompanied by significant economic losses for producers. ...Upon optimization of the experimental variables affecting the sensors performance, the A …
4-ethylphenol and 4-ethylguaicol levels in wine are associated to organoleptic defects that cause consumer rejection accompani …
Sorption of 4-ethylphenol and 4-ethylguaiacol by suberin from cork.
Gallardo-Chacón JJ, Karbowiak T. Gallardo-Chacón JJ, et al. Food Chem. 2015 Aug 15;181:222-6. doi: 10.1016/j.foodchem.2015.02.102. Epub 2015 Feb 26. Food Chem. 2015. PMID: 25794743
Cork shows an active role in the sorption of volatile phenols from wine. The sorption properties of 4-ethylphenol and 4-ethylguaiacol phenols in hydro-alcoholic medium placed in contact with suberin extracted from cork were especially investigated. ...Finally, the c …
Cork shows an active role in the sorption of volatile phenols from wine. The sorption properties of 4-ethylphenol and 4-ethylg …
4-Ethylphenol, 4-ethylguaiacol and 4-ethylcatechol in red wines: Microbial formation, prevention, remediation and overview of analytical approaches.
Milheiro J, Filipe-Ribeiro L, Vilela A, Cosme F, Nunes FM. Milheiro J, et al. Crit Rev Food Sci Nutr. 2019;59(9):1367-1391. doi: 10.1080/10408398.2017.1408563. Epub 2017 Dec 19. Crit Rev Food Sci Nutr. 2019. PMID: 29257912 Review.
The presence of 4-ethylphenol, 4-ethylguaiacol and 4-ethylcatechol in red wines affect negatively their aroma conferring horsy, barnyard, smoky and medicinal aromatic notes. ...
The presence of 4-ethylphenol, 4-ethylguaiacol and 4-ethylcatechol in red wines affect negatively their aroma conferrin …
Susceptibility of newborn rats to 3-ethylphenol and 4-ethylphenol compared with that of young rats.
Takahashi M, Hirata-Koizumi M, Nishimura N, Ito Y, Sunaga M, Fujii S, Kamata E, Hasegawa R, Ema M. Takahashi M, et al. Congenit Anom (Kyoto). 2006 Mar;46(1):26-33. doi: 10.1111/j.1741-4520.2006.00098.x. Congenit Anom (Kyoto). 2006. PMID: 16643596
Newborn rat studies were conducted with oral administration of 3-ethylphenol (3EP) and 4-ethylphenol (4EP) on postnatal days (PND) 4-21 to allow comparison of no observed adverse effect level (NOAEL) and unequivocally toxic level (UETL) with those from 28-day studie …
Newborn rat studies were conducted with oral administration of 3-ethylphenol (3EP) and 4-ethylphenol (4EP) on postnatal days ( …
4-ethylphenol and 4-ethylguaiacol in wines: estimating non-microbial sourced contributions and toxicological considerations.
Rayne S, Eggers NJ. Rayne S, et al. J Environ Sci Health B. 2007 Nov;42(8):887-97. doi: 10.1080/03601230701623365. J Environ Sci Health B. 2007. PMID: 17978957
Analyses of commercially available wines suggested non-Brettanomyces sources of 4-ethylphenol and 4-ethylguaiacol. Grapes, enological additions, exposure to plastics, and oak-barrel aging were potential inputs considered. ...A review of worldwide 4-ethylph …
Analyses of commercially available wines suggested non-Brettanomyces sources of 4-ethylphenol and 4-ethylguaiacol. Grapes, eno …
397 results