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Quoted phrase not found in phrase index: "steoroids"
Page 1
Thyroid hormone-like and estrogenic activity of hydroxylated PCBs in cell culture.
Kitamura S, Jinno N, Suzuki T, Sugihara K, Ohta S, Kuroki H, Fujimoto N. Kitamura S, et al. Toxicology. 2005 Mar 30;208(3):377-87. doi: 10.1016/j.tox.2004.11.037. Toxicology. 2005. PMID: 15695023
However, 4-hydroxy-2',4',6'-trichlorobiphenyl (4-OH-2',4',6'-TCB), 3-hydroxy-2,2',5,5'-tetrachlorobiphenyl, 4-hydroxy-2,2',5,5'-tetrachlorobiphenyl, 4-hydroxy-2,3,3',4'-tetrachlorobiphenyl, 2,3',5,5'-tetrachlorobiphenyl and 2,3',4',5,5'-p …
However, 4-hydroxy-2',4',6'-trichlorobiphenyl (4-OH-2',4',6'-TCB), 3-hydroxy-2,2',5,5'-tetrachloro …
Increase of oxytocin-induced oscillatory contractions by 4-hydroxy-2',4',6'-trichlorobiphenyl is estrogen receptor mediated.
Tsai ML, Webb RC, Loch-Caruso R. Tsai ML, et al. Biol Reprod. 1997 Feb;56(2):341-7. doi: 10.1095/biolreprod56.2.341. Biol Reprod. 1997. PMID: 9116132
Many lightly chlorinated PCBs are hydroxylated in vivo. The PCB congener 4-hydroxy-2',4',6'-trichlorobiphenyl (4-OH-TCB) has a high affinity for estrogen receptors and exerts a uterotropic effect in vivo. ...These data support the …
Many lightly chlorinated PCBs are hydroxylated in vivo. The PCB congener 4-hydroxy-2',4',6'-trichlorob …
4-hydroxy-2',4',6'-trichlorobiphenyl and 4-hydroxy-2',3',4',5'-tetrachlorobiphenyl are estrogenic in rainbow trout.
Carlson DB, Williams DE. Carlson DB, et al. Environ Toxicol Chem. 2001 Feb;20(2):351-8. Environ Toxicol Chem. 2001. PMID: 11351435
Many natural and synthetic xenobiotics are known to interact with endocrine systems of animals. Various hydroxylated metabolites of persistent polychlorinated biphenyl contaminants (hydroxy-polychlorinated biphenyls [OH-PCBs]) have been shown to have agonist or antagonist …
Many natural and synthetic xenobiotics are known to interact with endocrine systems of animals. Various hydroxylated metabolites of p …
Modulation of Cyclic AMP Levels in Fallopian Tube Cells by Natural and Environmental Estrogens.
Rosselli M, Cometti BPS, Leeners B, Szutkowska ME, Jackson EK, Dubey RK. Rosselli M, et al. Cells. 2021 May 19;10(5):1250. doi: 10.3390/cells10051250. Cells. 2021. PMID: 34069403 Free PMC article.
Autocrine/paracrine factors generated in response to 17beta-estradiol (E2) within the fallopian tube (FT) facilitate fertilization and early embryo development for implantation. ...E2 increased cAMP levels and CREB phosphorylation in FTCs, and these effects were mimicked b …
Autocrine/paracrine factors generated in response to 17beta-estradiol (E2) within the fallopian tube (FT) facilitate fertilization an …
Natural and environmental oestrogens induce TGFB1 synthesis in oviduct cells.
Cometti BPS, Dubey RK, Imthurn B, Rosselli M. Cometti BPS, et al. Reproduction. 2018 Mar;155(3):233-244. doi: 10.1530/REP-17-0425. Epub 2017 Dec 18. Reproduction. 2018. PMID: 29254988 Free article.
Here, we investigated whether oviduct cells synthesize TGFB1 and whether E2 and environmental oestrogens (EOEs; xenoestrogens and phytoestrogens) modulate its synthesis. Under basal conditions, bovine oviduct cells (OCs; oviduct epithelial cells and oviduct fibroblasts; 1: …
Here, we investigated whether oviduct cells synthesize TGFB1 and whether E2 and environmental oestrogens (EOEs; xenoestrogens and phy …
Differential activation of wild-type and variant forms of estrogen receptor alpha by synthetic and natural estrogenic compounds using a promoter containing three estrogen-responsive elements.
Yoon K, Pallaroni L, Stoner M, Gaido K, Safe S. Yoon K, et al. J Steroid Biochem Mol Biol. 2001 Jul;78(1):25-32. doi: 10.1016/s0960-0760(01)00070-x. J Steroid Biochem Mol Biol. 2001. PMID: 11530281
Structure-dependent estrogen receptor alpha (ER alpha) agonist and antagonist activities of synthetic and natural estrogenic compounds were investigated in human HepG2, MDA-MB-231 and U2 cancer cell lines. ...Results of this in vitro study suggest that the …
Structure-dependent estrogen receptor alpha (ER alpha) agonist and antagonist activities of synthetic and natural estrogenic c …
Estrogen receptor-binding activity of polychlorinated hydroxybiphenyls: conformationally restricted structural probes.
Korach KS, Sarver P, Chae K, McLachlan JA, McKinney JD. Korach KS, et al. Mol Pharmacol. 1988 Jan;33(1):120-6. Mol Pharmacol. 1988. PMID: 3122017
A series of polychlorinated hydroxybiphenyls (PCBs) has been tested for their binding activity to soluble uterine estrogen receptor protein. Competitive binding analysis was performed on 0-40% ammonium sulfate-enriched uterine cytosol receptor preparations which improved t …
A series of polychlorinated hydroxybiphenyls (PCBs) has been tested for their binding activity to soluble uterine estrogen receptor p …
Xeno-oestrogens and phyto-oestrogens induce the synthesis of leukaemia inhibitory factor by human and bovine oviduct cells.
Reinhart KC, Dubey RK, Keller PJ, Lauper U, Rosselli M. Reinhart KC, et al. Mol Hum Reprod. 1999 Oct;5(10):899-907. doi: 10.1093/molehr/5.10.899. Mol Hum Reprod. 1999. PMID: 10508216 Free article.
Therefore substances which are structurally similar to 17beta-oestradiol and possess oestrogenic activity may also modulate LIF synthesis and influence the reproductive process. We used primary cultures of bovine and human oviduct cells (epithelial cells:fibroblasts 1:1) t …
Therefore substances which are structurally similar to 17beta-oestradiol and possess oestrogenic activity may also modulate LIF synthesis an …
Congener-specific effects of PCBs on contractions of pregnant rat uteri.
Tsai ML, Webb RC, Loch-Caruso R. Tsai ML, et al. Reprod Toxicol. 1996 Jan-Feb;10(1):21-8. doi: 10.1016/0890-6238(95)02014-4. Reprod Toxicol. 1996. PMID: 8998381
After cumulative exposure to individual PCB congeners (0.5 microM to 150 microM), oscillatory contractions were: 1) not altered by 2,4,5,2',4',5'-hexachlorobiphenyl, 3,4,5,3',4'-pentachlorobiphenyl, or 3,4,3',4'-tetrachlorobiphenyl; 2) significantly inhibited by 4-hydro …
After cumulative exposure to individual PCB congeners (0.5 microM to 150 microM), oscillatory contractions were: 1) not altered by 2,4,5,2', …
Influence of 4-hydroxylated polychlorinated biphenyls on the secretory function of bovine ovarian cells: role of the steroidogenic factor-1 receptor.
Mlynarczuk J, Kotwica J. Mlynarczuk J, et al. Anim Reprod Sci. 2015 Apr;155:89-98. doi: 10.1016/j.anireprosci.2015.02.005. Epub 2015 Feb 12. Anim Reprod Sci. 2015. PMID: 25726440
The hydroxy-derivatives (OHPCBs) of polychlorinated biphenyls (PCBs) can accumulate in the tissues of the reproductive tract in animals and humans and may still have estrogen-like properties. Moreover, the "orphan" nuclear receptor Steroidogenic Factor-1 (SF-1) can …
The hydroxy-derivatives (OHPCBs) of polychlorinated biphenyls (PCBs) can accumulate in the tissues of the reproductive tract in anima …
11 results