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Quoted phrase not found in phrase index: "steoroids"
Page 1
Palladium-Catalyzed Phosphorylation of Aryl Mesylates and Tosylates.
Fu WC, So CM, Kwong FY. Fu WC, et al. Org Lett. 2015 Dec 4;17(23):5906-9. doi: 10.1021/acs.orglett.5b03104. Epub 2015 Nov 17. Org Lett. 2015. PMID: 26574778
The mesylated derivatives of biologically active compounds such as 17beta-estradiol and 6-hydroxyflavone are also shown to be applicable substrates. A one-pot phosphorylation-amination sequence is described for the facile synthesis of potential pharmacophores …
The mesylated derivatives of biologically active compounds such as 17beta-estradiol and 6-hydroxyflavone are also shown …
In vitro effects of some flavones on human pyruvate kinase isoenzyme M2.
Aslan E, Adem S. Aslan E, et al. J Biochem Mol Toxicol. 2015 Mar;29(3):109-13. doi: 10.1002/jbt.21673. Epub 2014 Nov 11. J Biochem Mol Toxicol. 2015. PMID: 25388478
Inhibitors and activators of this enzyme are suitable molecules for use in treating cancer. The aim of the present study was to investigate the effect of certain flavones on PKM2. Apigenin, wogonin, flavone, 3-hydroxyflavone, 5-hydroxyflavone, 6-hydroxyflavone …
Inhibitors and activators of this enzyme are suitable molecules for use in treating cancer. The aim of the present study was to inves …
Characterization of non-covalent binding of 6-hydroxyflavone and 5,7-dihydroxyflavone with bovine hemoglobin: Multi-spectroscopic and molecular docking analyses.
Das S, Karn A, Sarmah R, Rohman MA, Koley S, Ghosh P, Roy AS. Das S, et al. J Photochem Photobiol B. 2018 Jan;178:40-52. doi: 10.1016/j.jphotobiol.2017.10.021. Epub 2017 Oct 28. J Photochem Photobiol B. 2018. PMID: 29102848
Both 6-hydroxyflavone and chrysin can quench the intrinsic fluorescence intensity of BHb via static quenching mechanism. ...The binding distances from donor BHb to the acceptor ligands (6-hydroxyflavone and chrysin) were estimated using the Foster's th …
Both 6-hydroxyflavone and chrysin can quench the intrinsic fluorescence intensity of BHb via static quenching mechanism. ...Th …
Influence of amide versus ester linkages on the anticancer properties of the new flavone-biotin conjugates.
Stompor M, Świtalska M, Bajek A, Wietrzyk J. Stompor M, et al. Z Naturforsch C J Biosci. 2019 Jul 26;74(7-8):193-200. doi: 10.1515/znc-2018-0195. Z Naturforsch C J Biosci. 2019. PMID: 31100057
Novel biotinylated C-6 substituted flavones were synthesised by a one-step method that connects biotin to 6-hydroxyflavone and 6-aminoflavone by esterification and amidation of hydroxyl and amino groups, respectively. ...In vitro evaluation revealed that compounds w …
Novel biotinylated C-6 substituted flavones were synthesised by a one-step method that connects biotin to 6-hydroxyflavone and …
Novel Structurally Related Flavones Augment Cell Death Induced by rhsTRAIL.
Bronikowska J, Szliszka E, Kostrzewa-Susłow E, Jaworska D, Czuba ZP, Bednarski P, Król W. Bronikowska J, et al. Int J Mol Sci. 2017 Jun 6;18(6):1211. doi: 10.3390/ijms18061211. Int J Mol Sci. 2017. PMID: 28587286 Free PMC article.
TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) was identified as a powerful activator of apoptosis in tumor cells and one of the most promising candidates for cancer therapy with no toxicity against normal tissues. However, many tumor …
TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) was identified as a powerful activator of apoptosis in tumor c …
Flavonoids' Effects on Caenorhabditis elegans' Longevity, Fat Accumulation, Stress Resistance and Gene Modulation Involve mTOR, SKN-1 and DAF-16.
Guerrero-Rubio MA, Hernández-García S, García-Carmona F, Gandía-Herrero F. Guerrero-Rubio MA, et al. Antioxidants (Basel). 2021 Mar 12;10(3):438. doi: 10.3390/antiox10030438. Antioxidants (Basel). 2021. PMID: 33809299 Free PMC article.
In this work we describe the effects of six structurally-related flavonoids-baicalein, chrysin, scutellarein, 6-hydroxyflavone, 6,7-dihydroxyflavone and 7,8-dihydroxyflavone-on Caenorhabditis elegans' lifespan and stress resistance. The results showed that chrysin, …
In this work we describe the effects of six structurally-related flavonoids-baicalein, chrysin, scutellarein, 6-hydroxyflavone …
Secretion of cortisol and aldosterone as a vulnerable target for adrenal endocrine disruption - screening of 30 selected chemicals in the human H295R cell model.
Ullerås E, Ohlsson A, Oskarsson A. Ullerås E, et al. J Appl Toxicol. 2008 Nov;28(8):1045-53. doi: 10.1002/jat.1371. J Appl Toxicol. 2008. PMID: 18626888
Disruption of adrenal steroidogenesis and hormone secretion may cause serious effects on human health. A human in vitro model is needed to predict effects, and elucidate mechanisms of endocrine disruption and adrenal toxicity. ...Aminoglutethimide, prochloraz, ketoc …
Disruption of adrenal steroidogenesis and hormone secretion may cause serious effects on human health. A human in vitro model is need …
Identification of selective plant-derived natural carotenoid and flavonoids as the potential inhibitors of DHHC-mediated protein S-palmitoylation: an in silico study.
Chaturvedi S, Pandya N, Sadhukhan S, Sonawane A. Chaturvedi S, et al. J Biomol Struct Dyn. 2024 Feb 6:1-14. doi: 10.1080/07391102.2024.2306502. Online ahead of print. J Biomol Struct Dyn. 2024. PMID: 38319030
Protein S-palmitoylation mediated by DHHCs is recognized as a distinct and reversible form of lipid modification connected with several health perturbations, including neurodegenerative disorders, cancer, and autoimmune conditions. However, the pharmacological characterist …
Protein S-palmitoylation mediated by DHHCs is recognized as a distinct and reversible form of lipid modification connected with several heal …
Effects of flavonoid phytochemicals on cortisol production and on activities of steroidogenic enzymes in human adrenocortical H295R cells.
Ohno S, Shinoda S, Toyoshima S, Nakazawa H, Makino T, Nakajin S. Ohno S, et al. J Steroid Biochem Mol Biol. 2002 Mar;80(3):355-63. doi: 10.1016/s0960-0760(02)00021-3. J Steroid Biochem Mol Biol. 2002. PMID: 11948020
Daidzein-induced reduction of cortisol production by H295R cells was not inhibited by the estrogen receptor antagonist ICI 182,780. The flavonoids 6-hydroxyflavone, daidzein, genistein, biochanin A and formononetin strongly and significantly inhibited microso …
Daidzein-induced reduction of cortisol production by H295R cells was not inhibited by the estrogen receptor antagonist ICI 182,780. T …
16 results