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333 results

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Quoted phrase not found in phrase index: "steoroids"
Page 1
Rce1: mechanism and inhibition.
Hampton SE, Dore TM, Schmidt WK. Hampton SE, et al. Crit Rev Biochem Mol Biol. 2018 Apr;53(2):157-174. doi: 10.1080/10409238.2018.1431606. Epub 2018 Feb 9. Crit Rev Biochem Mol Biol. 2018. PMID: 29424242 Free PMC article. Review.
CaaX proteins, especially Ras, have been implicated in cancer, and understanding the post-translational modifications of CaaX proteins would provide insight into their biological function and regulation. ...Small-molecule inhibitor discovery is currently limited by the lac …
CaaX proteins, especially Ras, have been implicated in cancer, and understanding the post-translational modifications of CaaX protein …
Acrodermatitis enteropathica.
Neldner KH, Hambidge KM, Walravens PA. Neldner KH, et al. Int J Dermatol. 1978 Jun;17(5):380-7. doi: 10.1111/ijd.1978.17.5.380. Int J Dermatol. 1978. PMID: 96035 Review.
Acrodermatisis enteropathical has had a remarkable hist orical course beginning only 35 years ago, first passing through a period of empiric management with the 8-hydroxyquinoline drugs and culminating with the discovery of a biochemical effect in zinc absorption. . …
Acrodermatisis enteropathical has had a remarkable hist orical course beginning only 35 years ago, first passing through a period of empiric …
The toxicology of Clioquinol.
Mao X, Schimmer AD. Mao X, et al. Toxicol Lett. 2008 Nov 10;182(1-3):1-6. doi: 10.1016/j.toxlet.2008.08.015. Epub 2008 Sep 4. Toxicol Lett. 2008. PMID: 18812216 Review.
5-Chloro-7-iodo-quinolin-8-ol (Clioquinol) is a halogenated 8-hydroxyquinoline that was used in 1950-1970s as an oral anti-parasitic agent for the treatment and prevention of intestinal amebiasis. ...Such information will aid in the design of clinical trials of oral …
5-Chloro-7-iodo-quinolin-8-ol (Clioquinol) is a halogenated 8-hydroxyquinoline that was used in 1950-1970s as an oral anti-par …
Bis(amido)bis(oxinate)diamine Ligands for theranostic radiometals.
Southcott L, Whetter JN, Wharton L, Patrick BO, Zarschler K, Kubeil M, Stephan H, Jaraquemada-Peláez MG, Orvig C. Southcott L, et al. J Inorg Biochem. 2022 Jun;231:111789. doi: 10.1016/j.jinorgbio.2022.111789. Epub 2022 Mar 12. J Inorg Biochem. 2022. PMID: 35305407
Reported here are two novel, bis(amido)bis(oxinate)diamine ligands, H(2)amidohox (2,2'-(ethane-1,2-diylbis(((8-hydroxyquinolin-2-yl)methyl)azanediyl))diacetamide) and H(2)amidoC3hox (2,2'-(propane-1,3-diylbis(((8-hydroxyquinolin-2-yl)methyl)azanediyl))diacetamide), that combine t …
Reported here are two novel, bis(amido)bis(oxinate)diamine ligands, H(2)amidohox (2,2'-(ethane-1,2-diylbis(((8-hydroxyquinolin-2-yl)methyl)a …
Anti-tumor and cellular mechanisms of Hf(IV)tetra-(8-hydroxyquinolinato) complexes.
Zhao T, Mei D, Ma J, Liu N, Zhang Q, Yang Z, Correia I. Zhao T, et al. J Inorg Biochem. 2025 Sep;270:112945. doi: 10.1016/j.jinorgbio.2025.112945. Epub 2025 May 10. J Inorg Biochem. 2025. PMID: 40373563 Free article.
Three 8-hydroxyquinoline-stabilized hafnium complexes, [Hf(IV)(oxinate)(4)], were synthesized with good aqueous stability and solubility by reacting Hf(IV)Cl(4) with 8-hydroxyquinoline (HL(1)), 2-methyl-8-hydroxyquinoline (HL(2)) and 5-ch …
Three 8-hydroxyquinoline-stabilized hafnium complexes, [Hf(IV)(oxinate)(4)], were synthesized with good aqueous stability and …
Insights of 8-hydroxyquinolines: A novel target in medicinal chemistry.
Gupta R, Luxami V, Paul K. Gupta R, et al. Bioorg Chem. 2021 Mar;108:104633. doi: 10.1016/j.bioorg.2021.104633. Epub 2021 Jan 12. Bioorg Chem. 2021. PMID: 33513476 Review.
8-Hydroxyquinoline (8-HQ) is a significant heterocyclic scaffold in organic and analytical chemistry because of the properties of chromophore and is used to detect various metal ions and anions. ...Metal chelation properties of 8-hydroxyquinoline …
8-Hydroxyquinoline (8-HQ) is a significant heterocyclic scaffold in organic and analytical chemistry because of the pro …
H2pyhox - Octadentate Bis(pyridyloxine).
Southcott L, Wang X, Choudhary N, Wharton L, Patrick BO, Yang H, Zarschler K, Kubeil M, Stephan H, Jaraquemada-Peláez MG, Orvig C. Southcott L, et al. Inorg Chem. 2021 Aug 16;60(16):12186-12196. doi: 10.1021/acs.inorgchem.1c01412. Epub 2021 Jul 26. Inorg Chem. 2021. PMID: 34310113
A new versatile chelating ligand for intermediate size and softness radiometals [(64)Cu]Cu(2)(+) and [(111)In]In(3)(+), H(2)pyhox, was synthesized by introducing pyridine as a new donor moiety to complement 8-hydroxyquinoline on an ethylenediamine backbone. The comb …
A new versatile chelating ligand for intermediate size and softness radiometals [(64)Cu]Cu(2)(+) and [(111)In]In(3)(+), H(2)pyhox, was synth …
Insights of metal 8-hydroxylquinolinol complexes as the potential anticancer drugs.
Zhou X. Zhou X. J Inorg Biochem. 2023 Jan;238:112051. doi: 10.1016/j.jinorgbio.2022.112051. Epub 2022 Oct 27. J Inorg Biochem. 2023. PMID: 36327497 Review.
8-Hydroxyquinoline and its derivatives, which belong to a well-known class of quinoline based drugs with varied biological activities, have been extensively explored for the treatments of cancer, Alzheimer's disease, neurodegenerative diseases and other life- …
8-Hydroxyquinoline and its derivatives, which belong to a well-known class of quinoline based drugs with varied biological act …
Platinum(II) 5-substituted-8-hydroxyquinoline coordination compounds induces mitophagy-mediated apoptosis in A549/DDP cancer cells.
Yang Y, Du LQ, Huang Y, Liang CJ, Qin QP, Liang H. Yang Y, et al. J Inorg Biochem. 2023 Apr;241:112152. doi: 10.1016/j.jinorgbio.2023.112152. Epub 2023 Jan 28. J Inorg Biochem. 2023. PMID: 36736244
The cytotoxic activity of PtL1 and PtL2 were screened in both healthy HL-7702 cell line and cancer cell lines, human lung adenocarcinoma A549 cancer cells and cisplatin-resistant lung adenocarcinoma A549/DDP cancer cells (A549R), and were compared to that of …
The cytotoxic activity of PtL1 and PtL2 were screened in both healthy HL-7702 cell line and cancer cell lines, human lung adenocarcin …
Recent Advances in the Synthesis and Biological Activity of 8-Hydroxyquinolines.
Saadeh HA, Sweidan KA, Mubarak MS. Saadeh HA, et al. Molecules. 2020 Sep 21;25(18):4321. doi: 10.3390/molecules25184321. Molecules. 2020. PMID: 32967141 Free PMC article. Review.
Compounds containing the 8-hydroxyquinoline (8-HQ) 1 nucleus exhibit a wide range of biological activities, including antimicrobial, anticancer, and antifungal effects. ...In addition, several described compounds in this review could act leads for the develop …
Compounds containing the 8-hydroxyquinoline (8-HQ) 1 nucleus exhibit a wide range of biological activities, including a …
333 results