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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1977 1
1978 4
1979 2
1980 8
1981 9
1982 8
1983 21
1984 9
1985 20
1986 13
1987 33
1988 28
1989 31
1990 52
1991 52
1992 67
1993 60
1994 69
1995 69
1996 75
1997 130
1998 101
1999 120
2000 130
2001 113
2002 135
2003 166
2004 208
2005 215
2006 219
2007 252
2008 306
2009 322
2010 305
2011 366
2012 369
2013 464
2014 428
2015 438
2016 469
2017 484
2018 458
2019 430
2020 478
2021 466
2022 430
2023 400
2024 142

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8,269 results

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Page 1
Targeting DNA damage response pathways in cancer.
Groelly FJ, Fawkes M, Dagg RA, Blackford AN, Tarsounas M. Groelly FJ, et al. Nat Rev Cancer. 2023 Feb;23(2):78-94. doi: 10.1038/s41568-022-00535-5. Epub 2022 Dec 5. Nat Rev Cancer. 2023. PMID: 36471053 Review.
The sirtuin family in health and disease.
Wu QJ, Zhang TN, Chen HH, Yu XF, Lv JL, Liu YY, Liu YS, Zheng G, Zhao JQ, Wei YF, Guo JY, Liu FH, Chang Q, Zhang YX, Liu CG, Zhao YH. Wu QJ, et al. Signal Transduct Target Ther. 2022 Dec 29;7(1):402. doi: 10.1038/s41392-022-01257-8. Signal Transduct Target Ther. 2022. PMID: 36581622 Free PMC article. Review.
Mitochondrial sirtuins, metabolism, and aging.
Ji Z, Liu GH, Qu J. Ji Z, et al. J Genet Genomics. 2022 Apr;49(4):287-298. doi: 10.1016/j.jgg.2021.11.005. Epub 2021 Nov 29. J Genet Genomics. 2022. PMID: 34856390 Free article. Review.
SIRT7 in the aging process.
Lagunas-Rangel FA. Lagunas-Rangel FA. Cell Mol Life Sci. 2022 May 18;79(6):297. doi: 10.1007/s00018-022-04342-x. Cell Mol Life Sci. 2022. PMID: 35585284 Free PMC article. Review.
Design and Preclinical Evaluation of a Novel B7-H4-Directed Antibody-Drug Conjugate, AZD8205, Alone and in Combination with the PARP1-Selective Inhibitor AZD5305.
Kinneer K, Wortmann P, Cooper ZA, Dickinson NJ, Masterson L, Cailleau T, Hutchinson I, Vijayakrishnan B, McFarlane M, Ball K, Davies M, Lewis A, Huang Y, Rosenbaum AI, Yuan J, Chesebrough J, Anderton J, Monks N, Novick S, Wang J, Dimasi N, Christie RJ, Sabol D, Tosto FA, Wallez Y, Leo E, Albertella MR, Staniszewska AD, Tice DA, Howard PW, Luheshi N, Sapra P. Kinneer K, et al. Clin Cancer Res. 2023 Mar 14;29(6):1086-1101. doi: 10.1158/1078-0432.CCR-22-2630. Clin Cancer Res. 2023. PMID: 36355054
PARP1 associates with R-loops to promote their resolution and genome stability.
Laspata N, Kaur P, Mersaoui SY, Muoio D, Liu ZS, Bannister MH, Nguyen HD, Curry C, Pascal JM, Poirier GG, Wang H, Masson JY, Fouquerel E. Laspata N, et al. Nucleic Acids Res. 2023 Mar 21;51(5):2215-2237. doi: 10.1093/nar/gkad066. Nucleic Acids Res. 2023. PMID: 36794853 Free PMC article.
SIRT6 promotes DNA repair under stress by activating PARP1.
Mao Z, Hine C, Tian X, Van Meter M, Au M, Vaidya A, Seluanov A, Gorbunova V. Mao Z, et al. Science. 2011 Jun 17;332(6036):1443-6. doi: 10.1126/science.1202723. Science. 2011. PMID: 21680843 Free PMC article.
8,269 results