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1983 1
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2000 5
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2007 5
2008 7
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349 results

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Page 1
Association Between Consumption of Low- and No-Calorie Artificial Sweeteners and Cognitive Decline: An 8-Year Prospective Study.
Gonçalves NG, Martinez-Steele E, Lotufo PA, Bensenor I, Goulart AC, Barreto SM, Giatti L, de Faria CP, Molina MDCB, Caramelli P, Marchioni DM, Suemoto CK. Gonçalves NG, et al. Neurology. 2025 Oct 7;105(7):e214023. doi: 10.1212/WNL.0000000000214023. Epub 2025 Sep 3. Neurology. 2025. PMID: 40902134
A Food Frequency Questionnaire was used to calculate combined and individual consumption of 7 LNCSs (aspartame, saccharin, acesulfame k, erythritol, xylitol, sorbitol, and tagatose). We estimated z-scores across 6 cognitive tests. ...Consumption of aspartame, saccha …
A Food Frequency Questionnaire was used to calculate combined and individual consumption of 7 LNCSs (aspartame, saccharin, acesulfame …
Artificial sweeteners and cancer risk: Results from the NutriNet-Santé population-based cohort study.
Debras C, Chazelas E, Srour B, Druesne-Pecollo N, Esseddik Y, Szabo de Edelenyi F, Agaësse C, De Sa A, Lutchia R, Gigandet S, Huybrechts I, Julia C, Kesse-Guyot E, Allès B, Andreeva VA, Galan P, Hercberg S, Deschasaux-Tanguy M, Touvier M. Debras C, et al. PLoS Med. 2022 Mar 24;19(3):e1003950. doi: 10.1371/journal.pmed.1003950. eCollection 2022 Mar. PLoS Med. 2022. PMID: 35324894 Free PMC article.
In particular, aspartame (HR = 1.15 [95% CI 1.03 to 1.28], P = 0.002) and acesulfame-K (HR = 1.13 [95% CI 1.01 to 1.26], P = 0.007) were associated with increased cancer risk. ...CONCLUSIONS: In this large cohort study, artificial sweeteners (especially aspartame an …
In particular, aspartame (HR = 1.15 [95% CI 1.03 to 1.28], P = 0.002) and acesulfame-K (HR = 1.13 [95% CI 1.01 to 1.26], P = 0 …
Is the Use of Artificial Sweeteners Beneficial for Patients with Diabetes Mellitus? The Advantages and Disadvantages of Artificial Sweeteners.
Iizuka K. Iizuka K. Nutrients. 2022 Oct 22;14(21):4446. doi: 10.3390/nu14214446. Nutrients. 2022. PMID: 36364710 Free PMC article. Review.
Artificial sweeteners have been developed as substitutes for sugar. Sucralose, acesulfame K (ACE K), aspartame, and saccharin are artificial sweeteners. Previously, artificial sweeteners were thought to be effective in treating obesity and diabetes. ...
Artificial sweeteners have been developed as substitutes for sugar. Sucralose, acesulfame K (ACE K), aspartame, and saccharin …
The Combined Effects of Aspartame and Acesulfame-K Blends on Appetite: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
Mehat K, Chen Y, Corpe CP. Mehat K, et al. Adv Nutr. 2022 Dec 22;13(6):2329-2340. doi: 10.1093/advances/nmac072. Adv Nutr. 2022. PMID: 36056917 Free PMC article.
Aspartame (Asp) and acesulfame-K (Ace-K) are nonnutritive sweeteners (NNSs) commonly used in combination to replace added sugars in reduced- or low-calorie foods and beverages. ...
Aspartame (Asp) and acesulfame-K (Ace-K) are nonnutritive sweeteners (NNSs) commonly used in combination to replace added suga …
Effect of Non-Nutritive Sweeteners on the Gut Microbiota.
Conz A, Salmona M, Diomede L. Conz A, et al. Nutrients. 2023 Apr 13;15(8):1869. doi: 10.3390/nu15081869. Nutrients. 2023. PMID: 37111090 Free PMC article. Review.
We summarized the results from pre-clinical and clinical studies published over the last ten years that examined the single effects of the most consumed NNS: aspartame, acesulfame-K, sucralose, and saccharin. Pre-clinical studies have given conflicting results for v …
We summarized the results from pre-clinical and clinical studies published over the last ten years that examined the single effects of the m …
Mammalian sweet taste receptors.
Nelson G, Hoon MA, Chandrashekar J, Zhang Y, Ryba NJ, Zuker CS. Nelson G, et al. Cell. 2001 Aug 10;106(3):381-90. doi: 10.1016/s0092-8674(01)00451-2. Cell. 2001. PMID: 11509186 Free article.
Second, using a heterologous expression system, we demonstrate that T1R2 and T1R3 combine to function as a sweet receptor, recognizing sweet-tasting molecules as diverse as sucrose, saccharin, dulcin, and acesulfame-K. Finally, we present a detailed analysis of the …
Second, using a heterologous expression system, we demonstrate that T1R2 and T1R3 combine to function as a sweet receptor, recognizing sweet …
Understanding the link between aspartame and cancer.
Soffritti M. Soffritti M. Expert Rev Anticancer Ther. 2024 Sep;24(9):793-802. doi: 10.1080/14737140.2024.2383675. Epub 2024 Jul 31. Expert Rev Anticancer Ther. 2024. PMID: 39041328 Review.
Adequate long-term carcinogenicity bioassays on other diffuse artificial sweeteners such as acesulfame-k, sucralose, saccharin, including their blends, are likewise important for public health....
Adequate long-term carcinogenicity bioassays on other diffuse artificial sweeteners such as acesulfame-k, sucralose, saccharin …
Long-term metabolic effects of non-nutritive sweeteners.
Rathaus M, Azem L, Livne R, Ron S, Ron I, Hadar R, Efroni G, Amir A, Braun T, Haberman Y, Tirosh A. Rathaus M, et al. Mol Metab. 2024 Oct;88:101985. doi: 10.1016/j.molmet.2024.101985. Epub 2024 Jul 6. Mol Metab. 2024. PMID: 38977130 Free PMC article.
METHODS: To ensure consistent sweetness level and controlling for the acceptable daily intake (ADI), eight weeks old C57BL/6 male mice were administered with acesulfame K (ace K, 535.25 mg/L), aspartame (411.75 mg/L), sucralose (179.5 mg/L), saccharin (80 mg/L), or …
METHODS: To ensure consistent sweetness level and controlling for the acceptable daily intake (ADI), eight weeks old C57BL/6 male mice were …
Artificial Sweeteners and Risk of Type 2 Diabetes in the Prospective NutriNet-Santé Cohort.
Debras C, Deschasaux-Tanguy M, Chazelas E, Sellem L, Druesne-Pecollo N, Esseddik Y, Szabo de Edelenyi F, Agaësse C, De Sa A, Lutchia R, Julia C, Kesse-Guyot E, Allès B, Galan P, Hercberg S, Huybrechts I, Cosson E, Tatulashvili S, Srour B, Touvier M. Debras C, et al. Diabetes Care. 2023 Sep 1;46(9):1681-1690. doi: 10.2337/dc23-0206. Diabetes Care. 2023. PMID: 37490630 Free PMC article.
Positive associations were also observed for individual artificial sweeteners: aspartame (HR 1.63 [95% CI 1.38-1.93], P-trend <0.001), acesulfame-K (HR 1.70 [1.42-2.04], P-trend <0.001), and sucralose (HR 1.34 [1.07-1.69], P-trend = 0.013). ...
Positive associations were also observed for individual artificial sweeteners: aspartame (HR 1.63 [95% CI 1.38-1.93], P-trend <0.001), …
Non-sugar sweeteners and cancer: Toxicological and epidemiological evidence.
Pavanello S, Moretto A, La Vecchia C, Alicandro G. Pavanello S, et al. Regul Toxicol Pharmacol. 2023 Mar;139:105369. doi: 10.1016/j.yrtph.2023.105369. Epub 2023 Mar 3. Regul Toxicol Pharmacol. 2023. PMID: 36870410 Free article. Review.
The toxicological section includes the evaluation of genotoxicity and carcinogenicity data for acesulfame K, advantame, aspartame, cyclamates, saccharin, steviol glycosides and sucralose. ...
The toxicological section includes the evaluation of genotoxicity and carcinogenicity data for acesulfame K, advantame, aspart …
349 results