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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1986 3
1991 1
1992 4
1993 8
1994 4
1995 5
1996 6
1997 6
1998 6
1999 4
2000 7
2001 8
2002 6
2003 8
2004 5
2005 7
2006 13
2007 13
2008 4
2009 6
2010 8
2011 16
2012 17
2013 10
2014 11
2015 11
2016 6
2017 14
2018 9
2019 8
2020 7
2021 3
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219 results
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Page 1
Protective Effects of Melatonin on the Skin: Future Perspectives.
Rusanova I, Martínez-Ruiz L, Florido J, Rodríguez-Santana C, Guerra-Librero A, Acuña-Castroviejo D, Escames G. Rusanova I, et al. Among authors: acuna castroviejo d. Int J Mol Sci. 2019 Oct 8;20(19):4948. doi: 10.3390/ijms20194948. Int J Mol Sci. 2019. PMID: 31597233 Free PMC article. Review.
Extrapineal melatonin: sources, regulation, and potential functions.
Acuña-Castroviejo D, Escames G, Venegas C, Díaz-Casado ME, Lima-Cabello E, López LC, Rosales-Corral S, Tan DX, Reiter RJ. Acuña-Castroviejo D, et al. Cell Mol Life Sci. 2014 Aug;71(16):2997-3025. doi: 10.1007/s00018-014-1579-2. Epub 2014 Feb 20. Cell Mol Life Sci. 2014. PMID: 24554058 Review.
Clinical trial to test the efficacy of melatonin in COVID-19.
Acuña-Castroviejo D, Escames G, Figueira JC, de la Oliva P, Borobia AM, Acuña-Fernández C. Acuña-Castroviejo D, et al. J Pineal Res. 2020 Oct;69(3):e12683. doi: 10.1111/jpi.12683. Epub 2020 Aug 8. J Pineal Res. 2020. PMID: 32770854 Free PMC article.
Melatonin, clock genes and mitochondria in sepsis.
Acuña-Castroviejo D, Rahim I, Acuña-Fernández C, Fernández-Ortiz M, Solera-Marín J, Sayed RKA, Díaz-Casado ME, Rusanova I, López LC, Escames G. Acuña-Castroviejo D, et al. Cell Mol Life Sci. 2017 Nov;74(21):3965-3987. doi: 10.1007/s00018-017-2610-1. Epub 2017 Aug 7. Cell Mol Life Sci. 2017. PMID: 28785808 Review.
Combination of melatonin and rapamycin for head and neck cancer therapy: Suppression of AKT/mTOR pathway activation, and activation of mitophagy and apoptosis via mitochondrial function regulation.
Shen YQ, Guerra-Librero A, Fernandez-Gil BI, Florido J, García-López S, Martinez-Ruiz L, Mendivil-Perez M, Soto-Mercado V, Acuña-Castroviejo D, Ortega-Arellano H, Carriel V, Diaz-Casado ME, Reiter RJ, Rusanova I, Nieto A, López LC, Escames G. Shen YQ, et al. Among authors: acuna castroviejo d. J Pineal Res. 2018 Apr;64(3). doi: 10.1111/jpi.12461. Epub 2018 Jan 9. J Pineal Res. 2018. PMID: 29247557
Melatonin Enhances Cisplatin and Radiation Cytotoxicity in Head and Neck Squamous Cell Carcinoma by Stimulating Mitochondrial ROS Generation, Apoptosis, and Autophagy.
Fernandez-Gil BI, Guerra-Librero A, Shen YQ, Florido J, Martínez-Ruiz L, García-López S, Adan C, Rodríguez-Santana C, Acuña-Castroviejo D, Quiñones-Hinojosa A, Fernández-Martínez J, Abdel Moneim AE, López LC, Rodríguez Ferrer JM, Escames G. Fernandez-Gil BI, et al. Among authors: acuna castroviejo d. Oxid Med Cell Longev. 2019 Feb 28;2019:7187128. doi: 10.1155/2019/7187128. eCollection 2019. Oxid Med Cell Longev. 2019. PMID: 30944696 Free PMC article.
Melatonin/Nrf2/NLRP3 Connection in Mouse Heart Mitochondria during Aging.
Fernández-Ortiz M, Sayed RKA, Fernández-Martínez J, Cionfrini A, Aranda-Martínez P, Escames G, de Haro T, Acuña-Castroviejo D. Fernández-Ortiz M, et al. Among authors: acuna castroviejo d. Antioxidants (Basel). 2020 Nov 27;9(12):1187. doi: 10.3390/antiox9121187. Antioxidants (Basel). 2020. PMID: 33260800 Free PMC article.
A phase II, single-center, double-blind, randomized placebo-controlled trial to explore the efficacy and safety of intravenous melatonin in patients with COVID-19 admitted to the intensive care unit (MelCOVID study): a structured summary of a study protocol for a randomized controlled trial.
Rodríguez-Rubio M, Figueira JC, Acuña-Castroviejo D, Borobia AM, Escames G, de la Oliva P. Rodríguez-Rubio M, et al. Among authors: acuna castroviejo d. Trials. 2020 Aug 5;21(1):699. doi: 10.1186/s13063-020-04632-4. Trials. 2020. PMID: 32758298 Free PMC article. Clinical Trial.
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