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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1954 7
1955 16
1956 10
1957 22
1958 26
1959 21
1960 18
1961 31
1962 13
1963 2
1964 6
1965 31
1966 78
1967 85
1968 157
1969 163
1970 158
1971 221
1972 232
1973 215
1974 266
1975 239
1976 246
1977 271
1978 182
1979 137
1980 134
1981 150
1982 145
1983 171
1984 192
1985 230
1986 227
1987 236
1988 286
1989 306
1990 295
1991 343
1992 316
1993 357
1994 407
1995 430
1996 454
1997 586
1998 633
1999 641
2000 687
2001 758
2002 781
2003 917
2004 897
2005 1019
2006 1154
2007 1265
2008 1359
2009 1367
2010 1538
2011 1712
2012 2003
2013 2062
2014 2069
2015 1996
2016 1797
2017 1658
2018 1674
2019 772
2020 10
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Search Results

33,916 results
Results by year
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Page 1
Identification of potential crucial genes associated with carcinogenesis of clear cell renal cell carcinoma
Song E, et al. J Cell Biochem 2018. PMID 29227586
Signaling pathway analyses indicated that DEGs had common pathways in signal transduction, metabolism, and immune system. Third, hub genes were identified with protein-protein interaction (PPI) network, including PTPRC, TGFB1, EGF, MYC, ITGB2, CTSS, FN1, CCL5, KNG1, and CD86. ...
Signaling pathway analyses indicated that DEGs had common pathways in signal transduction, metabolism, and immune system. Third, hub …
Matrix stiffness and tumor-associated macrophages modulate epithelial to mesenchymal transition of human adenocarcinoma cells.
Alonso-Nocelo M, et al. Biofabrication 2018. PMID 29595143 Free PMC article.
In this work, we develop a 3D co-culture model of lung adenocarcinoma cells and macrophages in an interpenetrating network hydrogel, to investigate the influence of the macrophage phenotype and ECM stiffness in the induction of EMT. ...
In this work, we develop a 3D co-culture model of lung adenocarcinoma cells and macrophages in an interpenetrating network hydrogel, …
Gene expression-based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study.
Director's Challenge Consortium for the Molecular Classification of Lung Adenocarcinoma , et al. Nat Med 2008 - Clinical Trial. PMID 18641660 Free PMC article.
Here we report a large, training-testing, multi-site, blinded validation study to characterize the performance of several prognostic models based on gene expression for 442 lung adenocarcinomas. ...This study also provides the largest available set of microarray data with extensive pathological and clinical annotation for lung adenocarcinomas....
Here we report a large, training-testing, multi-site, blinded validation study to characterize the performance of several prognostic models …
KIF5B-RET Oncoprotein Signals through a Multi-kinase Signaling Hub
Das TK and Cagan RL. Cell Rep 2017. PMID 28877471 Free PMC article.
The KIF5B-RET gene has been identified as a primary driver in a subset of lung adenocarcinomas. Targeting human KIF5B-RET to epithelia in Drosophila directed multiple aspects of transformation, including hyperproliferation, epithelial-to-mesenchymal transition, invasion, and extension of striking invadopodia-like processes. ...
The KIF5B-RET gene has been identified as a primary driver in a subset of lung adenocarcinomas. Targeting human KIF5B-RET to epitheli …
Desmoplasia in Primary Tumors and Metastatic Lesions of Pancreatic Cancer
Whatcott CJ, et al. Clin Cancer Res 2015. PMID 25695692 Free PMC article.
PURPOSE: Pancreatic ductal adenocarcinoma (PDAC) is characterized by high levels of fibrosis, termed desmoplasia, which is thought to hamper the efficacy of therapeutics treating PDAC. ...
PURPOSE: Pancreatic ductal adenocarcinoma (PDAC) is characterized by high levels of fibrosis, termed desmoplasia, which is thought to …
Metabolite profiling stratifies pancreatic ductal adenocarcinomas into subtypes with distinct sensitivities to metabolic inhibitors.
Daemen A, et al. Proc Natl Acad Sci U S A 2015. PMID 26216984 Free PMC article.
Although targeting cancer metabolism is a promising therapeutic strategy, clinical success will depend on an accurate diagnostic identification of tumor subtypes with specific metabolic requirements. Through broad metabolite profiling, we successfully identified three highly distinct metabolic subtypes in pancreatic ductal adenocarcinoma (PDAC). ...
Although targeting cancer metabolism is a promising therapeutic strategy, clinical success will depend on an accurate diagnostic iden …
33,916 results
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