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Year Number of Results
2012 2
2014 2
2015 3
2016 2
2018 2
2019 1
2020 0
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Page 1
Structure-Based Design, Synthesis, and In Vivo Antinociceptive Effects of Selective A1 Adenosine Receptor Agonists.
Petrelli R, Scortichini M, Belardo C, Boccella S, Luongo L, Capone F, Kachler S, Vita P, Del Bello F, Maione S, Lavecchia A, Klotz KN, Cappellacci L. Petrelli R, et al. J Med Chem. 2018 Jan 11;61(1):305-318. doi: 10.1021/acs.jmedchem.7b01399. Epub 2018 Jan 3. J Med Chem. 2018. PMID: 29257884
Novel Irreversible Agonists Acting at the A1 Adenosine Receptor.
Jörg M, Glukhova A, Abdul-Ridha A, Vecchio EA, Nguyen AT, Sexton PM, White PJ, May LT, Christopoulos A, Scammells PJ. Jörg M, et al. J Med Chem. 2016 Dec 22;59(24):11182-11194. doi: 10.1021/acs.jmedchem.6b01561. Epub 2016 Dec 13. J Med Chem. 2016. PMID: 27958734
Synthesis and biological evaluation of novel allosteric enhancers of the A1 adenosine receptor based on 2-amino-3-(4'-chlorobenzoyl)-4-substituted-5-arylethynyl thiophene.
Romagnoli R, Baraldi PG, IJzerman AP, Massink A, Cruz-Lopez O, Lopez-Cara LC, Saponaro G, Preti D, Aghazadeh Tabrizi M, Baraldi S, Moorman AR, Vincenzi F, Borea PA, Varani K. Romagnoli R, et al. J Med Chem. 2014 Sep 25;57(18):7673-86. doi: 10.1021/jm5008853. Epub 2014 Sep 12. J Med Chem. 2014. PMID: 25181013
5'-C-Ethyl-tetrazolyl-N(6)-substituted adenosine and 2-chloro-adenosine derivatives as highly potent dual acting A1 adenosine receptor agonists and A3 adenosine receptor antagonists.
Petrelli R, Torquati I, Kachler S, Luongo L, Maione S, Franchetti P, Grifantini M, Novellino E, Lavecchia A, Klotz KN, Cappellacci L. Petrelli R, et al. J Med Chem. 2015 Mar 12;58(5):2560-6. doi: 10.1021/acs.jmedchem.5b00074. Epub 2015 Feb 27. J Med Chem. 2015. PMID: 25699637
Synthesis and biological evaluation of a new series of 2-amino-3-aroyl thiophene derivatives as agonist allosteric modulators of the A1 adenosine receptor. A position-dependent effect study.
Romagnoli R, Baraldi PG, Lopez-Cara C, Cruz-Lopez O, Moorman AR, Massink A, IJzerman AP, Vincenzi F, Borea PA, Varani K. Romagnoli R, et al. Eur J Med Chem. 2015 Aug 28;101:185-204. doi: 10.1016/j.ejmech.2015.06.041. Epub 2015 Jun 24. Eur J Med Chem. 2015. PMID: 26141910
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