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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1951 1
1952 3
1953 5
1954 7
1955 9
1956 10
1957 11
1958 14
1959 31
1960 26
1961 50
1962 45
1963 5
1964 12
1965 99
1966 192
1967 249
1968 239
1969 248
1970 293
1971 247
1972 268
1973 266
1974 267
1975 283
1976 279
1977 280
1978 283
1979 295
1980 307
1981 333
1982 338
1983 342
1984 324
1985 334
1986 336
1987 332
1988 296
1989 328
1990 333
1991 265
1992 295
1993 240
1994 166
1995 199
1996 206
1997 230
1998 198
1999 254
2000 237
2001 272
2002 283
2003 319
2004 381
2005 479
2006 520
2007 552
2008 614
2009 640
2010 713
2011 834
2012 906
2013 1045
2014 1135
2015 1142
2016 1012
2017 1089
2018 1001
2019 383
2020 3
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21,342 results
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Page 1
Factors involved in white-to-brown adipose tissue conversion and in thermogenesis: a review.
Montanari T, et al. Obes Rev 2017 - Review. PMID 28187240
After the demonstration of functional brown adipose tissue in human adults, great effort is being devoted to develop therapies based on the adipose tissue itself, through the conversion of fat-accumulating white adipose tissue into energy-dissipating brown adipose tissue. ...In the present review, we summarize the current knowledge about the various molecules that can be applied in promoting white-to-brown adipose tissue conversion and energy expenditure and the cellular mechanisms involved....
After the demonstration of functional brown adipose tissue in human adults, great effort is being devoted to develop therapies …
Adipose tissue in control of metabolism.
Luo L and Liu M. J Endocrinol 2016 - Review. PMID 27935822
On one hand, adipose tissue stores energy in the form of lipid and controls the lipid mobilization and distribution in the body. ...In this review, we will summarize the recent findings of adipose tissue in the control of metabolism, focusing on its endocrine and thermogenic function....
On one hand, adipose tissue stores energy in the form of lipid and controls the lipid mobilization and distribution in the bod …
Adipose tissue dysfunction in cancer cachexia.
Daas SI, et al. J Cell Physiol 2018 - Review. PMID 30078199
Adipose tissue, a main player in cancer cachexia, is an essential metabolic and secretory organ consisting of both white adipose tissue (WAT) and brown adipose tissue. ...Furthermore, this review describes how adipose tissue becomes inflamed in cancer, shedding light on the combinatorial action of multiple secreted macromolecules, cytokines, hormones, and tumor mediators on adipose tissue dysfunction. ...
Adipose tissue, a main player in cancer cachexia, is an essential metabolic and secretory organ consisting of both white ad
Alcohol, Adipose Tissue and Lipid Dysregulation.
Steiner JL and Lang CH. Biomolecules 2017. PMID 28212318 Free PMC article.
Chronic alcohol consumption perturbs lipid metabolism as it increases adipose tissue lipolysis and leads to ectopic fat deposition within the liver and the development of alcoholic fatty liver disease. In addition to the recognition of the role of adipose tissue derived fatty acids in liver steatosis, alcohol also impacts other functions of adipose tissue and lipid metabolism. ...
Chronic alcohol consumption perturbs lipid metabolism as it increases adipose tissue lipolysis and leads to ectopic fat …
Secretory function of adipose tissue.
Kuryszko J, et al. Pol J Vet Sci 2016 - Review. PMID 27487522
There are two kinds of adipose tissue in mammals: white adipose tissue - WAT and brown adipose tissue - BAT. The main function of WAT is accumulation of triacylglycerols whereas the function of BAT is heat generation. ...This means that excess of adipose tissue, especially visceral adipose tissue, leads to the development of a chronic subclinical inflammatory condition, which favours the development of insulin resistance and Type 2 diabetes. ...
There are two kinds of adipose tissue in mammals: white adipose tissue - WAT and brown adipose tissue
White Adipose Tissue Browning: A Double-edged Sword.
Abdullahi A and Jeschke MG. Trends Endocrinol Metab 2016 - Review. PMID 27397607 Free PMC article.
The study of white adipose tissue (WAT) 'browning' has become a 'hot topic' in various acute and chronic metabolic conditions, based on the idea that WAT browning might be able to facilitate weight loss and improve metabolic health. ...
The study of white adipose tissue (WAT) 'browning' has become a 'hot topic' in various acute and chronic metabolic conditions, …
Adipose tissue - morphological and biochemical characteristic of different depots.
Murawska-Ciałowicz E. Postepy Hig Med Dosw (Online) 2017 - Review. PMID 28665277
Adipose tissue is not only a tissue which stores fat and plays a protective role. It is an important endocrine organ where signals sent from different tissues are generated and integrated. Adipose tissue is both morphologically and physiologically differentiated. However, due to their plasticity, adipocytes can undergo a transformation and change their structure and metabolism depending on the physiological state of the organism and the conditions to which it is exposed....
Adipose tissue is not only a tissue which stores fat and plays a protective role. It is an important endocrine organ wh
Dynamics of adipose tissue turnover in human metabolic health and disease.
White U and Ravussin E. Diabetologia 2019 - Review. PMID 30267179 Free PMC article.
White adipose tissue is a highly plastic organ and is an important regulator of whole-body metabolism and energy balance. The magnitude of adipose tissue mass is determined by dynamic changes in the synthesis and breakdown (i.e. turnover) of adipocytes and triacylglycerols (TGs). ...Finally, the role of adipose tissue turnover in metabolic health and disease is discussed....
White adipose tissue is a highly plastic organ and is an important regulator of whole-body metabolism and energy balanc …
Brown Adipose Tissue Activation Is Linked to Distinct Systemic Effects on Lipid Metabolism in Humans.
Chondronikola M, et al. Cell Metab 2016 - Clinical Trial. PMID 27238638 Free PMC article.
Recent studies suggest that brown adipose tissue (BAT) plays a role in energy and glucose metabolism in humans. However, the physiological significance of human BAT in lipid metabolism remains unknown. ...BAT volume was significantly associated with increased whole-body lipolysis, triglyceride-free fatty acid (FFA) cycling, FFA oxidation, and adipose tissue insulin sensitivity. ...
Recent studies suggest that brown adipose tissue (BAT) plays a role in energy and glucose metabolism in humans. However …
Biology of upper-body and lower-body adipose tissue--link to whole-body phenotypes.
Karpe F and Pinnick KE. Nat Rev Endocrinol 2015 - Review. PMID 25365922
The distribution of adipose tissue in the body has wide-ranging and reproducible associations with health and disease. Accumulation of adipose tissue in the upper body (abdominal obesity) is associated with the development of cardiovascular disease, insulin resistance, type 2 diabetes mellitus and even all-cause mortality. ...New data suggest that the profound functional differences between the upper-body and lower-body tissues are controlled by site-specific sets of developmental genes, such as HOXA6, HOXA5, HOXA3, IRX2 and TBX5 in subcutaneous abdominal adipose tissue and HOTAIR, SHOX2 and HOXC11 in gluteofemoral adipose tissue, which are under epigenetic control. ...
The distribution of adipose tissue in the body has wide-ranging and reproducible associations with health and disease. Accumul …
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