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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1976 8
1977 37
1978 38
1979 41
1980 38
1981 32
1982 32
1983 23
1984 30
1985 32
1986 36
1987 54
1988 80
1989 118
1990 82
1991 23
1992 28
1993 19
1994 18
1995 45
1996 39
1997 26
1998 20
1999 23
2000 28
2001 22
2002 24
2003 36
2004 23
2005 17
2006 17
2007 19
2008 20
2009 12
2010 29
2011 41
2012 45
2013 53
2014 46
2015 38
2016 31
2017 33
2018 32
2019 10
2020 0
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1,428 results
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Breathing responses produced by optogenetic stimulation of adrenergic C1 neurons are dependent on the connection with preBötzinger complex in rats.
Malheiros-Lima MR, et al. Pflugers Arch 2018. PMID 30054719
Optogenetic stimulation of the adrenergic C1 neurons produces cardiorespiratory activation, and selective depletion of these cells attenuates breathing responses induced by hypoxia. ...Functional connection between C1 cells and preBötC was evaluated by photostimulation of ChR2-transduced C1 neurons before and after unilateral injection of the ionotropic glutamate antagonist, kynurenic acid (kyn), or cocktail of adrenergic antagonists in the preBötC. ...
Optogenetic stimulation of the adrenergic C1 neurons produces cardiorespiratory activation, and selective depletion of these c …
Resilience to chronic stress is mediated by noradrenergic regulation of dopamine neurons.
Isingrini E, et al. Nat Neurosci 2016. PMID 26878672
Dopamine (DA) neurons in the ventral tegmental area (VTA) help mediate stress susceptibility and resilience. However, upstream mechanisms controlling these neurons remain unknown. ...Here we demonstrate that NE neurons regulate vulnerability to social defeat through inhibitory control of VTA DA neurons....
Dopamine (DA) neurons in the ventral tegmental area (VTA) help mediate stress susceptibility and resilience. However, upstream mechan …
Phenylethanolamine N-methyltransferase gene expression in adrenergic neurons of spontaneously hypertensive rats.
Grandbois J, et al. Neurosci Lett 2016. PMID 27769893
Epinephrine is synthesised by the catecholamine biosynthetic enzyme, phenylethanolamine N-methyltransferase (PNMT), primarily in chromaffin cells of the adrenal medulla and secondarily in brainstem adrenergic neurons of the medulla oblongata. ...Adrenergic neurons are responsible for blood pressure regulation and are the only PNMT containing neurons in the brainstem. The purpose of the current study was to determine whether elevated blood pressure found in adult spontaneously hypertensive rats (SHR) is associated with altered regulation of the PNMT gene in catecholaminergic neurons. ...
Epinephrine is synthesised by the catecholamine biosynthetic enzyme, phenylethanolamine N-methyltransferase (PNMT), primarily in chromaffin …
Electrophysiological characterization of putative C1 adrenergic neurons in the rat.
Haselton JR and Guyenet PG. Neuroscience 1989. PMID 2747912
It appears that only one of these populations consists of C1 adrenergic neurons. The present study used both double-labeling (one retrograde tracer and immunohistochemistry) and triple-labeling (two retrograde tracers and immunohistochemistry) to determine if C1 adrenergic neurons, which are immunoreactive for phenylethanolamine N-methyltransferase, exhibit a projection pattern that is sufficiently unique to permit the electrophysiological discrimination between C1 adrenergic and non-adrenergic neurons in the nucleus reticularis rostroventrolateralis. ...It is concluded that this subgroup of adrenergic neurons probably subserves a vasomotor function....
It appears that only one of these populations consists of C1 adrenergic neurons. The present study used both double-labeling ( …
Selective tracking of FFAR3-expressing neurons supports receptor coupling to N-type calcium channels in mouse sympathetic neurons.
Colina C, et al. Sci Rep 2018. PMID 30478340 Free PMC article.
Heterogeneity of FFAR3 expression in sympathetic neurons, however, renders single neurons studies extremely time-consuming in wild-type mice. ...Whole-cell patch-clamp recordings of identified FFAR3-expressing neurons from reporter mice revealed a 2.5-fold decrease in the Ca(V)2.2-FFAR3 inhibitory coupling variability and 1.5-fold increase in the mean I(Ca)(2+) inhibition, when compared with unlabeled neurons from wild-type mice. ...
Heterogeneity of FFAR3 expression in sympathetic neurons, however, renders single neurons studies extremely time-consuming in …
Molecular and Functional Sex Differences of Noradrenergic Neurons in the Mouse Locus Coeruleus.
Mulvey B, et al. Cell Rep 2018. PMID 29791834 Free PMC article.
Despite roles for noradrenergic neurons in behavior and neuropsychiatric disease models, their molecular characterization has lagged. We profiled mouse noradrenergic neurons in vivo, defining over 3,000 high-confidence transcripts expressed therein, including druggable receptors. ...
Despite roles for noradrenergic neurons in behavior and neuropsychiatric disease models, their molecular characterization has lagged. …
Cutaneous adrenergic nerve blockade attenuates sweating during incremental exercise in habitually trained men.
Amano T, et al. J Appl Physiol (1985) 2018. PMID 30024338 Free article.
It remains unknown whether cutaneous adrenergic nerves functionally contribute to sweat production during exercise. This study examined whether cutaneous adrenergic nerve blockade attenuates sweating during incremental exercise, specifically in habitually trained individuals. ...NEW & NOTEWORTHY We demonstrated for the first time that cutaneous adrenergic nerves do modulate sweating during high-intensity exercise in humans (≥70% maximum workload). ...
It remains unknown whether cutaneous adrenergic nerves functionally contribute to sweat production during exercise. This study examin …
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