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Year Number of Results
1991 1
1992 14
1993 20
1994 13
1995 11
1996 7
1997 11
1998 14
1999 8
2000 15
2001 14
2002 15
2003 18
2004 14
2005 11
2006 15
2007 11
2008 10
2009 13
2010 24
2011 35
2012 32
2013 28
2014 33
2015 26
2016 16
2017 17
2018 16
2019 14
2020 0
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Page 1
Changes of microbial cell survival, metabolic activity, efflux capacity, and quorum sensing ability of Aggregatibacter actinomycetemcomitans due to antimicrobial photodynamic therapy-induced bystander effects.
Mahdizade-Ari M, et al. Photodiagnosis Photodyn Ther 2019. PMID 31026616
MATERIALS AND METHODS: Bystander effects induced by whole bacterial cell suspension (WBCS(T)), cell-free supernatants fluid (CFSF(T)), and bacterial cell pellet (BCP(T)) obtained from A. actinomycetemcomitans culture treated with Cur-aPDT on cell survival, quorum sensing (QS) ability, metabolic activity and efflux capacity of A. actinomycetemcomitans were determined using microbial viability assay, Escherichia coli-based bioassay, XTT reduction method, and ethidium bromide (EtBr) accumulation assay, respectively. ...A. actinomycetemcomitans exposed to WBCS(T), CFSF(T), and BCP(T) showed a reduction of 83.2% (P = 0.001), 77.2% (P = 0.01) and 21.9% (P = 0.09) in the QS mediator compared to the WBCS(U), CFSF(U), and BCP(U) of untreated A. actinomycetemcomitans, respectively. ...
MATERIALS AND METHODS: Bystander effects induced by whole bacterial cell suspension (WBCS(T)), cell-free supernatants fluid (CFSF(T)) …
Microbiological and clinical effects of probiotics and antibiotics on nonsurgical treatment of chronic periodontitis: a randomized placebo- controlled trial with 9-month follow-up.
Morales A, et al. J Appl Oral Sci 2018 - Clinical Trial. PMID 29364340 Free PMC article.
The aim of this double-blind, placebo-controlled and parallel- arm randomized clinical trial was to evaluate the effects of Lactobacillus rhamnosus SP1-containing probiotic sachet and azithromycin tablets as an adjunct to nonsurgical therapy in clinical parameters and in presence and levels of Tannerella forsythia, Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans. ...
The aim of this double-blind, placebo-controlled and parallel- arm randomized clinical trial was to evaluate the effects of Lactobaci …
A successful antimicrobial therapeutic strategy for the discitis caused by Aggregatibacter actinomycetemcomitans under unknown drug susceptibility: A case report.
Uno S, et al. J Infect Chemother 2018. PMID 29685853
Aggregatibacter actinomycetemcomitans is well-known as the pathogen of gingivitis or periodontitis, and discitis or vertebral osteomyelitis cases caused by this organism have rarely been reported. ...Levofloxacin, which A. actinomycetemcomitans is usually susceptible to, can be an effective alternative oral antimicrobial agent in such cases....
Aggregatibacter actinomycetemcomitans is well-known as the pathogen of gingivitis or periodontitis, and discitis or vertebral
Aggregatibacter actinomycetemcomitans serotype prevalence and antibiotic resistance in a UK population with periodontitis.
Akrivopoulou C, et al. J Glob Antimicrob Resist 2017. PMID 28668698
OBJECTIVES: Aggregatibacter actinomycetemcomitans is a recognised pathogen involved in aggressive periodontitis. Seven serotypes of A. actinomycetemcomitans exist with a range of virulence and distribution dependent on ethnicity and geography. ...METHODS: Serotypes of A. actinomycetemcomitans isolates from a UK cohort of 50 patients with aggressive periodontitis were determined by PCR. ...
OBJECTIVES: Aggregatibacter actinomycetemcomitans is a recognised pathogen involved in aggressive periodontitis. Seven serotyp …
Dual action of highbush blueberry proanthocyanidins on Aggregatibacter actinomycetemcomitans and the host inflammatory response.
Ben Lagha A, et al. BMC Complement Altern Med 2018. PMID 29321009 Free PMC article.
The present study investigated the effects of highbush blueberry proanthocyanidins (PACs) on the virulence properties of Aggregatibacter actinomycetemcomitans and macrophage-associated inflammatory responses. ...RESULTS: Highbush blueberry PACs reduced the growth of A. actinomycetemcomitans and prevented biofilm formation at sub-inhibitory concentrations. ...
The present study investigated the effects of highbush blueberry proanthocyanidins (PACs) on the virulence properties of Aggregati
TdeA, a TolC-like protein required for toxin and drug export in Aggregatibacter (Actinobacillus) actinomycetemcomitans.
Crosby JA and Kachlany SC. Gene 2007. PMID 17116373 Free PMC article.
Aggregatibacter actinomycetemcomitans is an oral bacterium that causes localized aggressive periodontitis (LAP) and extra-oral infections such as sub-acute infective endocarditis. ...Inactivation of macB in A. actinomycetemcomitans did not alter the drug sensitivity profile or the hemolytic activity of the mutant. ...
Aggregatibacter actinomycetemcomitans is an oral bacterium that causes localized aggressive periodontitis (LAP) and extra-oral
Antimicrobial effect of platelet-rich plasma and platelet-rich fibrin
Badade PS, et al. Indian J Dent Res 2016. PMID 27411660 Free article.
The antimicrobial activity of PRP and PRF was evaluated by microbial culturing using bacterial strains of Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans. RESULTS: P. gingivalis and A. actinomycetemcomitans were inhibited by PRP but not by PRF. CONCLUSIONS: PRP is a potentially useful substance in the fight against periodontal pathogens. ...
The antimicrobial activity of PRP and PRF was evaluated by microbial culturing using bacterial strains of Porphyromonas gingivalis and Ag
Effects of low-dose doxycycline on cytokine secretion in human monocytes stimulated with Aggregatibacter actinomycetemcomitans.
Bostanci N, et al. Cytokine 2011. PMID 21962932 Free article.
Apart from its antimicrobial properties, this drug also has independent anti-inflammatory effects at sub-antimicrobial doses. The present study aimed to investigate the effects of low-doses of doxycycline (LDD) on cytokine production by human monocytic cells challenged with the periodontal pathogen Aggregatibacter actinomycetemcomitans, for up to 6 h. ...
Apart from its antimicrobial properties, this drug also has independent anti-inflammatory effects at sub-antimicrobial doses. …
Microbiologic Response to Periodontal Therapy and Multivariable Prediction of Clinical Outcome
Mombelli A, et al. J Periodontol 2017. PMID 28844191
BACKGROUND: This study assesses the microbiologic effects of a two-phase antimicrobial periodontal therapy and tested microbiologic, clinical, and biologic markers as prognostic indicators for clinical success. ...Aggregatibacter actinomycetemcomitans and Parvimonas micra (Pm) showed a significant decrease only if the treatment was supplemented with antibiotics, i.e., T1 in group A, or T2 in group B. ...
BACKGROUND: This study assesses the microbiologic effects of a two-phase antimicrobial periodontal therapy and tested microbiologic, …
Antimicrobial Efficacy of Photodynamic Therapy and Light-Activated Disinfection Against Bacterial Species on Titanium Dental Implants
Azizi B, et al. Int J Oral Maxillofac Implants 2018. PMID 30024999
MATERIALS AND METHODS: The study was conducted on 72 titanium dental implants contaminated with a bacterial suspension prepared from three bacterial species: Prevotella intermedia, Aggregatibacter actinomycetemcomitans, and Porphyromonas gingivalis. ...
MATERIALS AND METHODS: The study was conducted on 72 titanium dental implants contaminated with a bacterial suspension prepared from three b …
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