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Akkermansia muciniphila: paradigm for next-generation beneficial microorganisms.
Cani PD, Depommier C, Derrien M, Everard A, de Vos WM. Cani PD, et al. Nat Rev Gastroenterol Hepatol. 2022 Oct;19(10):625-637. doi: 10.1038/s41575-022-00631-9. Epub 2022 May 31. Nat Rev Gastroenterol Hepatol. 2022. PMID: 35641786 Review.
Ever since Akkermansia muciniphila was discovered and characterized two decades ago, numerous studies have shown that the lack or decreased abundance of this commensal bacterium was linked with multiple diseases (such as obesity, diabetes, liver steatosis, inflammat …
Ever since Akkermansia muciniphila was discovered and characterized two decades ago, numerous studies have shown that the lack …
Akkermansia muciniphila is a promising probiotic.
Zhang T, Li Q, Cheng L, Buch H, Zhang F. Zhang T, et al. Microb Biotechnol. 2019 Nov;12(6):1109-1125. doi: 10.1111/1751-7915.13410. Epub 2019 Apr 21. Microb Biotechnol. 2019. PMID: 31006995 Free PMC article. Review.
Akkermansia muciniphila (A. muciniphila), an intestinal symbiont colonizing in the mucosal layer, is considered to be a promising candidate as probiotics. ...
Akkermansia muciniphila (A. muciniphila), an intestinal symbiont colonizing in the mucosal layer, is considered to be a promis …
Akkermansia muciniphila and Gut Immune System: A Good Friendship That Attenuates Inflammatory Bowel Disease, Obesity, and Diabetes.
Rodrigues VF, Elias-Oliveira J, Pereira ÍS, Pereira JA, Barbosa SC, Machado MSG, Carlos D. Rodrigues VF, et al. Front Immunol. 2022 Jul 7;13:934695. doi: 10.3389/fimmu.2022.934695. eCollection 2022. Front Immunol. 2022. PMID: 35874661 Free PMC article. Review.
Akkermansia muciniphila is a Gram-negative anaerobic mucus-layer-degrading bacterium that colonizes the intestinal mucosa of humans and rodents. ...
Akkermansia muciniphila is a Gram-negative anaerobic mucus-layer-degrading bacterium that colonizes the intestinal mucosa of h …
Akkermansia muciniphila: biology, microbial ecology, host interactions and therapeutic potential.
Ioannou A, Berkhout MD, Geerlings SY, Belzer C. Ioannou A, et al. Nat Rev Microbiol. 2025 Mar;23(3):162-177. doi: 10.1038/s41579-024-01106-1. Epub 2024 Oct 15. Nat Rev Microbiol. 2025. PMID: 39406893 Review.
Akkermansia muciniphila is a gut bacterium that colonizes the gut mucosa, has a role in maintaining gut health and shows promise for potential therapeutic applications. ...
Akkermansia muciniphila is a gut bacterium that colonizes the gut mucosa, has a role in maintaining gut health and shows promi …
Quercetin-Driven Akkermansia Muciniphila Alleviates Obesity by Modulating Bile Acid Metabolism via an ILA/m(6)A/CYP8B1 Signaling.
Liu J, Liu Y, Huang C, He C, Yang T, Ren R, Xin Z, Wang X. Liu J, et al. Adv Sci (Weinh). 2025 Mar;12(12):e2412865. doi: 10.1002/advs.202412865. Epub 2025 Jan 31. Adv Sci (Weinh). 2025. PMID: 39888270 Free PMC article.
Here in this study, it is demonstrated that quercetin intervention significantly reverses obesity-related phenotypes through reshaping the overall structure of microbiota, especially boosting colonization of the beneficial gut commensal Akkermansia muciniphila (A. m …
Here in this study, it is demonstrated that quercetin intervention significantly reverses obesity-related phenotypes through reshaping the o …
Akkermansia muciniphila in neuropsychiatric disorders: friend or foe?
Lei W, Cheng Y, Gao J, Liu X, Shao L, Kong Q, Zheng N, Ling Z, Hu W. Lei W, et al. Front Cell Infect Microbiol. 2023 Jul 10;13:1224155. doi: 10.3389/fcimb.2023.1224155. eCollection 2023. Front Cell Infect Microbiol. 2023. PMID: 37492530 Free PMC article. Review.
An accumulating body of evidence suggests that the bacterium Akkermansia muciniphila exhibits positive systemic effects on host health, mainly by improving immunological and metabolic functions, and it is therefore regarded as a promising potential probiotic. ...
An accumulating body of evidence suggests that the bacterium Akkermansia muciniphila exhibits positive systemic effects on hos …
Akkermansia muciniphila supplementation in patients with overweight/obese type 2 diabetes: Efficacy depends on its baseline levels in the gut.
Zhang Y, Liu R, Chen Y, Cao Z, Liu C, Bao R, Wang Y, Huang S, Pan S, Qin L, Wang J, Ning G, Wang W. Zhang Y, et al. Cell Metab. 2025 Mar 4;37(3):592-605.e6. doi: 10.1016/j.cmet.2024.12.010. Epub 2025 Jan 28. Cell Metab. 2025. PMID: 39879980 Free article. Clinical Trial.
Akkermansia muciniphila is a promising target for managing obesity and type 2 diabetes (T2D), but human studies are limited. ...
Akkermansia muciniphila is a promising target for managing obesity and type 2 diabetes (T2D), but human studies are limited. . …
Akkermansia muciniphila improve cognitive dysfunction by regulating BDNF and serotonin pathway in gut-liver-brain axis.
Kang EJ, Cha MG, Kwon GH, Han SH, Yoon SJ, Lee SK, Ahn ME, Won SM, Ahn EH, Suk KT. Kang EJ, et al. Microbiome. 2024 Sep 28;12(1):181. doi: 10.1186/s40168-024-01924-8. Microbiome. 2024. PMID: 39342324 Free PMC article.
BACKRGROUND: Akkermansia muciniphila, a next-generation probiotic, is known as a cornerstone regulating the gut-organ axis in various diseases, but the underlying mechanism remains poorly understood. ...
BACKRGROUND: Akkermansia muciniphila, a next-generation probiotic, is known as a cornerstone regulating the gut-organ axis in …
The role of Akkermansia muciniphila in inflammatory bowel disease: Current knowledge and perspectives.
Zheng M, Han R, Yuan Y, Xing Y, Zhang W, Sun Z, Liu Y, Li J, Mao T. Zheng M, et al. Front Immunol. 2023 Jan 6;13:1089600. doi: 10.3389/fimmu.2022.1089600. eCollection 2022. Front Immunol. 2023. PMID: 36685588 Free PMC article. Review.
Recent accumulated evidence has revealed the involvement of mucin-degrading bacterium Akkermansia muciniphila (A. muciniphila) in the regulation of host barrier function and immune response, and how reduced intestinal colonisation of probiotic A. muciniphila can con …
Recent accumulated evidence has revealed the involvement of mucin-degrading bacterium Akkermansia muciniphila (A. muciniphila) …
Akkermansia muciniphila protects the intestine from irradiation-induced injury by secretion of propionic acid.
He KY, Lei XY, Wu DH, Zhang L, Li JQ, Li QT, Yin WT, Zhao ZL, Liu H, Xiang XY, Zhu LJ, Cui CY, Wang KK, Wang JH, Lv L, Sun QH, Liu GL, Xu ZX, Jian YP. He KY, et al. Gut Microbes. 2023 Dec;15(2):2293312. doi: 10.1080/19490976.2023.2293312. Epub 2023 Dec 12. Gut Microbes. 2023. PMID: 38087436 Free PMC article.
Intestinal dysbiosis frequently occurs in abdominal radiotherapy and contributes to irradiation (IR)-induced intestinal damage and inflammation. Akkermansia muciniphila (A. muciniphila) is a recently characterized probiotic, which is critical for maintaining the dyn …
Intestinal dysbiosis frequently occurs in abdominal radiotherapy and contributes to irradiation (IR)-induced intestinal damage and inflammat …
2,378 results