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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1955 2
1956 3
1957 10
1958 25
1959 36
1960 28
1961 28
1962 84
1963 283
1964 370
1965 225
1966 282
1967 328
1968 362
1969 420
1970 391
1971 489
1972 476
1973 494
1974 534
1975 453
1976 309
1977 297
1978 287
1979 330
1980 285
1981 282
1982 293
1983 279
1984 331
1985 373
1986 341
1987 301
1988 322
1989 347
1990 452
1991 475
1992 445
1993 475
1994 533
1995 499
1996 518
1997 570
1998 535
1999 543
2000 596
2001 568
2002 622
2003 655
2004 692
2005 770
2006 865
2007 1006
2008 999
2009 1026
2010 1028
2011 1102
2012 1251
2013 1227
2014 1209
2015 1145
2016 1095
2017 1034
2018 926
2019 419
2020 10
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Search Results

31,029 results
Results by year
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Page 1
Acute Alcoholic Hepatitis
Im GY. Clin Liver Dis 2019 - Review. PMID 30454835
Treatment is mostly supportive. The short-term prognosis of acute alcoholic hepatitis depends on liver recovery, and ranges widely from rapid improvement to grim multiorgan failure despite treatment. ...Recent advances in the treatment of alcoholic hepatitis have solidified corticosteroids as the cornerstone of treatment to enhance short-term survival, but not intermediate or long-term survival....
Treatment is mostly supportive. The short-term prognosis of acute alcoholic hepatitis depends on liver recovery, and ranges widely fr
Association of adverse perinatal outcomes of intrahepatic cholestasis of pregnancy with biochemical markers: results of aggregate and individual patient data meta-analyses
Ovadia C, et al. Lancet 2019. Among authors: Tripodi V, Tribe R. PMID 30773280 Free PMC article.
In singleton pregnancies, stillbirth was associated with maximum total bile acid concentration (area under the receiver operating characteristic curve [ROC AUC]) 0·83 [95% CI 0·74-0·92]), but not alanine aminotransferase (ROC AUC 0·46 [0·35-0·57]). ...FUNDING: Tommy's, ICP Support, UK National Institute of Health Research, Wellcome Trust, and Genesis Research Trust....
In singleton pregnancies, stillbirth was associated with maximum total bile acid concentration (area under the receiver operating characteri …
AST to ALT ratio and arterial stiffness in non-fatty liver Japanese population:a secondary analysis based on a cross-sectional study
Liu Y, et al. Lipids Health Dis 2018 - Review. PMID 30509277 Free PMC article.
However, there are fewer investigations of the correlations between the aspartate aminotransferase (AST) to alanine aminotransferase (ALT) ratio and brachial ankle pulse wave velocity (baPWV). ...In addition, the trend was the opposite in subjects who consumed excessive amounts of alcohol....
However, there are fewer investigations of the correlations between the aspartate aminotransferase (AST) to alanine aminotransferase …
De Ritis Ratio (Aspartate Transaminase/Alanine Transaminase) as a Significant Prognostic Factor in Patients Undergoing Radical Cystectomy with Bladder Urothelial Carcinoma: A Propensity Score-Matched Study.
Yuk HD, et al. Dis Markers 2019. PMID 31534562 Free PMC article.
INTRODUCTION: To investigate the correlation between preoperative De Ritis ratio (aspartate transaminase (AST)/alanine transaminase (ALT)) and postoperative outcome in patients with urothelial cell carcinoma (UC) treated with radical cystectomy. ...CONCLUSION: Preoperative AST/ALT ratio could be an independent prognostic factor in patients with UC treated with radical cystectomy....
INTRODUCTION: To investigate the correlation between preoperative De Ritis ratio (aspartate transaminase (AST)/alanine tran
A review of the utility of tacrolimus in the management of adults with autoimmune hepatitis
Hanouneh M, et al. Scand J Gastroenterol 2019 - Review. PMID 30650311
Complete biochemical response was defined as normalisation of aspartate aminotransferase (AST <45) and alanine aminotransferase (ALT <50). ...Treatment duration ranged from 1 to 136 months. Indications for therapy were mostly AIH refractory to steroid treatment or inability to tolerate standard steroid treatment. ...
Complete biochemical response was defined as normalisation of aspartate aminotransferase (AST <45) and alanine aminotransferase (A …
Safe and effective superoxide dismutase 1 silencing using artificial microRNA in macaques
Borel F, et al. Sci Transl Med 2018. PMID 30381409
About 10% of cases are caused by gain-of-function mutations that are transmitted as dominant traits. A potential therapy for these cases is to suppress the expression of the mutant gene. ...These results support the notion that gene therapy with an artificial miRNA targeting SOD1 is safe and merits further development for the treatment of mutant SOD1-linked ALS....
About 10% of cases are caused by gain-of-function mutations that are transmitted as dominant traits. A potential therapy for t …
A Randomized, Controlled Trial of Vitamin D Supplementation on Cardiovascular Risk Factors, Hormones, and Liver Markers in Women with Polycystic Ovary Syndrome.
Javed Z, et al. Nutrients 2019 - Clinical Trial. PMID 30658483 Free PMC article.
This randomized, double-blind, placebo-controlled study explored the effect of vitamin D supplementation on cardiovascular risk factors (high-sensitivity C-reactive protein (hs-CRP), weight, body mass index (BMI), lipid profile, glucose levels, insulin levels, the homeostatic model assessment-insulin resistance (HOMA-IR), hormones (free androgen index (FAI), testosterone, sex hormone binding globulin (SHBG), and liver markers (alanine aminotransferase (ALT), hyaluronic acid (HA), N-terminal pro-peptide of type III procollagen (PIIINP), tissue inhibitor of metallo-proteinases-1 (TIMP-1), and the enhanced liver fibrosis (ELF) score). ...
This randomized, double-blind, placebo-controlled study explored the effect of vitamin D supplementation on cardiovascular risk factors (hig …
Meta-analysis of overall incidence and risk of ALK inhibitors-induced liver toxicities in advanced non-small-cell lung cancer
Li J, et al. Medicine (Baltimore) 2019 - Review. PMID 30608384 Free PMC article.
The incidences of all-grade alanine transaminase (ALT) and aspartate aminotransferase (AST) elevation were 26.0% (95% CI: 17.4%-37%), and 23.2% (95% CI, 16.7%-31.4%), respectively. ...CONCLUSIONS: The findings of the present study offer substantial evidence that ALK inhibitors treatment in advanced NSCLC significantly increases the risk of developing all-grade and high-grade liver toxicities in comparison with controls. ...
The incidences of all-grade alanine transaminase (ALT) and aspartate aminotransferase (AST) elevation were 26.0% (95% CI: 17.4 …
Tandospirone-Induced Rhabdomyolysis
Miyazaki K, et al. Clin Neuropharmacol 2018. PMID 30204599
Lactate dehydrogenase, aspartate aminotransferase, and alanine transaminase levels were also abnormal. After a fluid infusion was initiated and tandospirone was discontinued, most of her symptoms and abnormal laboratory data resolved within 10 days. ...
Lactate dehydrogenase, aspartate aminotransferase, and alanine transaminase levels were also abnormal. After a fluid infusion …
Independent effect of alanine transaminase on the incidence of type 2 diabetes mellitus, stratified by age and gender: A secondary analysis based on a large cohort study in China.
Gao F, et al. Clin Chim Acta 2019. PMID 30946812
BACKGROUND: Previous studies have revealed that alanine aminotransferase (ALT) may be one of the risk factors of developing diabetes. ...
BACKGROUND: Previous studies have revealed that alanine aminotransferase (ALT) may be one of the risk factors of developing diabetes. …
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