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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1789 3
1790 1
1791 1
1792 2
1796 1
1797 3
1799 2
1800 5
1802 1
1803 2
1804 1
1805 1
1806 8
1807 3
1808 1
1809 3
1810 2
1811 2
1812 2
1813 1
1814 4
1816 4
1817 3
1818 1
1819 3
1820 1
1821 4
1822 1
1823 2
1824 1
1825 1
1826 2
1827 2
1828 5
1829 8
1830 7
1831 3
1832 5
1833 7
1834 3
1835 2
1836 3
1837 5
1838 6
1839 8
1840 9
1841 12
1842 15
1843 17
1844 16
1845 15
1846 11
1847 26
1848 5
1849 10
1850 11
1851 5
1852 6
1853 11
1854 6
1855 13
1856 13
1857 11
1858 8
1859 15
1860 8
1861 11
1862 7
1863 5
1864 5
1865 5
1866 8
1867 5
1868 7
1869 7
1870 7
1871 12
1872 12
1873 6
1874 6
1875 8
1876 9
1877 15
1878 7
1879 9
1880 16
1881 11
1882 13
1883 17
1884 18
1885 17
1886 16
1887 18
1888 20
1889 27
1890 15
1891 15
1892 22
1893 18
1894 6
1895 9
1896 14
1897 17
1898 30
1899 19
1900 13
1901 18
1902 25
1903 15
1904 25
1905 22
1906 25
1907 29
1908 25
1909 41
1910 30
1911 60
1912 49
1913 49
1914 55
1915 45
1916 67
1917 41
1918 46
1919 43
1920 47
1921 48
1922 49
1923 50
1924 70
1925 50
1926 52
1927 86
1928 68
1929 70
1930 91
1931 101
1932 88
1933 87
1934 87
1935 123
1936 104
1937 130
1938 135
1939 109
1940 106
1941 126
1942 98
1943 72
1944 150
1945 453
1946 1280
1947 1479
1948 1695
1949 1552
1950 1964
1951 2470
1952 2689
1953 3267
1954 3369
1955 3598
1956 3559
1957 4002
1958 4338
1959 4696
1960 4904
1961 5409
1962 5870
1963 7913
1964 11104
1965 10141
1966 10665
1967 13443
1968 16076
1969 18202
1970 19723
1971 23599
1972 27038
1973 30168
1974 33606
1975 37250
1976 37917
1977 38382
1978 39750
1979 42732
1980 44772
1981 46675
1982 49247
1983 53823
1984 57900
1985 62128
1986 65160
1987 70348
1988 77083
1989 87718
1990 94499
1991 98265
1992 104552
1993 109852
1994 117068
1995 121037
1996 123751
1997 126537
1998 132185
1999 136274
2000 145552
2001 151870
2002 155843
2003 165171
2004 177890
2005 192421
2006 205045
2007 211992
2008 223489
2009 234271
2010 251188
2011 269305
2012 285472
2013 299908
2014 312925
2015 323564
2016 325810
2017 333857
2018 346177
2019 357408
2020 388883
2021 402435
2022 369674
2023 345462
2024 357320
2025 3555
2026 4

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8,341,829 results

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Quoted phrases not found in phrase index: "Priority Journal", "Glioblastoma Metabolism Pathology Radionuclide Imaging", "Integrin Alphavbeta3 Analysis Metabolism", "Iodine Radioisotopes Diagnostic Use Metabolism", "Oligopeptides Analysis Metabolism", "Peptides Chemistry Metabolism"
Page 1
Clinical Application of Radiolabeled RGD Peptides for PET Imaging of Integrin alphavbeta3.
Chen H, Niu G, Wu H, Chen X. Chen H, et al. Theranostics. 2016 Jan 1;6(1):78-92. doi: 10.7150/thno.13242. eCollection 2016. Theranostics. 2016. PMID: 26722375 Free PMC article. Review.
Besides, many other interventions that involve the change of blood vessel/tumor microenvironment would also benefit from such imaging strategies. Of the imaging techniques that target angiogenesis, radiolabeled Arg-Gly-Asp (RGD) peptides have been a major foc …
Besides, many other interventions that involve the change of blood vessel/tumor microenvironment would also benefit from such imaging …
alphavbeta3 Integrin-Targeted Peptide/Peptidomimetic-Drug Conjugates: In-Depth Analysis of the Linker Technology.
Dal Corso A, Pignataro L, Belvisi L, Gennari C. Dal Corso A, et al. Curr Top Med Chem. 2016;16(3):314-29. doi: 10.2174/1568026615666150701114343. Curr Top Med Chem. 2016. PMID: 26126915 Free article. Review.
Due to its overexpression on blood vessels of human tumors, alphavbeta3 integrin is one of the most studied receptors of tumor-targeted therapeutics: several peptides and peptidomimetics, bearing the RGD (Arg-Gly-Asp) recognition sequence, have been de …
Due to its overexpression on blood vessels of human tumors, alphavbeta3 integrin is one of the most studied receptors o …
Molecular Imaging of Breast Cancer: Role of RGD Peptides.
Chakravarty R, Chakraborty S, Dash A. Chakravarty R, et al. Mini Rev Med Chem. 2015;15(13):1073-94. doi: 10.2174/1389557515666150909144606. Mini Rev Med Chem. 2015. PMID: 26349490 Review.
The integrin alphavbeta3 plays an important role in breast cancer angiogenesis and is expressed on tumor endothelial cells as well as on some tumor cells. ...Using RGD-based probes, several preclinical studies have employed different imaging mod …
The integrin alphavbeta3 plays an important role in breast cancer angiogenesis and is expressed on tumor endothelial cells as …
alphaVbeta3 Integrin-Targeted Radionuclide Therapy with 64Cu-cyclam-RAFT-c(-RGDfK-)4.
Jin ZH, Furukawa T, Degardin M, Sugyo A, Tsuji AB, Yamasaki T, Kawamura K, Fujibayashi Y, Zhang MR, Boturyn D, Dumy P, Saga T. Jin ZH, et al. Mol Cancer Ther. 2016 Sep;15(9):2076-85. doi: 10.1158/1535-7163.MCT-16-0040. Epub 2016 Jul 15. Mol Cancer Ther. 2016. PMID: 27422811
The transmembrane cell adhesion receptor alphaVbeta3 integrin (alphaVbeta3) has been identified as an important molecular target for cancer imaging and therapy. ...Here, we subsequently evaluated its therapeutic potential and side effects …
The transmembrane cell adhesion receptor alphaVbeta3 integrin (alphaVbeta3) has been identified as an imp …
An (18)F-Labeled Poly(ADP-ribose) Polymerase Positron Emission Tomography Imaging Agent.
Zmuda F, Blair A, Liuzzi MC, Malviya G, Chalmers AJ, Lewis D, Sutherland A, Pimlott SL. Zmuda F, et al. J Med Chem. 2018 May 10;61(9):4103-4114. doi: 10.1021/acs.jmedchem.8b00138. Epub 2018 Apr 19. J Med Chem. 2018. PMID: 29630818 Free PMC article.
Poly(ADP-ribose) polymerase (PARP) is involved in repair of DNA breaks and is over-expressed in a wide variety of tumors, making PARP an attractive biomarker for positron emission tomography (PET) and single photon emission computed tomography imaging. …
Poly(ADP-ribose) polymerase (PARP) is involved in repair of DNA breaks and is over-expressed in a wide variety of tumors, making PARP an att …
Radionuclide imaging of tumor angiogenesis.
Dijkgraaf I, Boerman OC. Dijkgraaf I, et al. Cancer Biother Radiopharm. 2009 Dec;24(6):637-47. doi: 10.1089/cbr.2009.0694. Cancer Biother Radiopharm. 2009. PMID: 20025543 Review.
Several ligands targeting these markers have been tested as a radiotracer for imaging angiogenesis in tumors. The potential of some of these tracers, such as radiolabeled cyclic RGD peptides and radiolabeled anti-PSMA antibodies, has already been tested in cancer pa …
Several ligands targeting these markers have been tested as a radiotracer for imaging angiogenesis in tumors. The potential of some o …
Analysis of the CD23-alphav integrin interaction: a study with model peptides.
Edkins AL, Borland G, Kelly SM, Cogdell RJ, Ozanne BW, Cushley W. Edkins AL, et al. Biochem Biophys Res Commun. 2012 Jun 1;422(2):207-12. doi: 10.1016/j.bbrc.2012.04.076. Epub 2012 Apr 27. Biochem Biophys Res Commun. 2012. PMID: 22560905
The human CD23 protein binds to alphavbeta3 and alphavbeta5 integrins. The integrins recognize a short tripeptide motif of arg-lys-cys (RKC) in CD23, and peptides containing this motif inhibit the binding of CD23 to B cells and monocytes; neither fibronectin, …
The human CD23 protein binds to alphavbeta3 and alphavbeta5 integrins. The integrins recognize a short tripeptide motif of arg …
alphavbeta3-integrin-mediated adhesion is regulated through an AAK1L- and EHD3-dependent rapid-recycling pathway.
Waxmonsky NC, Conner SD. Waxmonsky NC, et al. J Cell Sci. 2013 Aug 15;126(Pt 16):3593-601. doi: 10.1242/jcs.122465. Epub 2013 Jun 18. J Cell Sci. 2013. PMID: 23781025 Free PMC article.
Protein transport through the endosome is critical for maintaining proper integrin cell surface integrin distribution to support cell adhesion, motility and viability. ...We discovered that two early endosome factors, AAK1L and EHD3, are critical for …
Protein transport through the endosome is critical for maintaining proper integrin cell surface integrin distribution to suppo …
D2A sequence of the urokinase receptor induces cell growth through alphavbeta3 integrin and EGFR.
Eden G, Archinti M, Arnaudova R, Andreotti G, Motta A, Furlan F, Citro V, Cubellis MV, Degryse B. Eden G, et al. Cell Mol Life Sci. 2018 May;75(10):1889-1907. doi: 10.1007/s00018-017-2718-3. Epub 2017 Nov 28. Cell Mol Life Sci. 2018. PMID: 29184982 Free PMC article.
The urokinase receptor (uPAR) stimulates cell proliferation by forming a macromolecular complex with alphavbeta3 integrin and the epidermal growth factor receptor (EGFR, ErbB1 or HER1) that we name the uPAR proliferasome. uPAR transactivates EGFR, which in turn medi …
The urokinase receptor (uPAR) stimulates cell proliferation by forming a macromolecular complex with alphavbeta3 integrin and …
Molecular dynamics simulations to the bidirectional adhesion signaling pathway of integrin alpha(V) beta(3).
Kulke M, Langel W. Kulke M, et al. Proteins. 2020 May;88(5):679-688. doi: 10.1002/prot.25849. Epub 2019 Nov 18. Proteins. 2020. PMID: 31693219
The bidirectional force transmission process of integrin through the cell membrane is still not well understood. Several possible mechanisms have been discussed in literature on the basis of experimental data, and in this study, we investigate these mechanism …
The bidirectional force transmission process of integrin through the cell membrane is still not well understood. Severa …
8,341,829 results
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