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Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1785 4
1801 3
1812 2
1813 3
1816 1
1818 1
1819 1
1820 1
1821 1
1822 2
1823 3
1825 1
1826 5
1827 7
1828 2
1841 3
1842 6
1843 4
1846 2
1847 1
1848 1
1849 1
1850 3
1851 2
1852 4
1853 5
1855 3
1856 4
1857 2
1858 5
1859 1
1860 1
1861 3
1862 4
1863 1
1864 7
1865 3
1866 8
1867 1
1868 3
1869 7
1870 4
1871 4
1872 10
1873 5
1874 2
1875 2
1876 5
1877 1
1878 2
1879 4
1880 2
1881 1
1882 6
1883 4
1884 2
1885 3
1886 5
1887 5
1888 1
1889 3
1890 5
1891 9
1892 2
1893 5
1894 5
1895 3
1896 6
1897 6
1898 3
1899 2
1900 1
1901 2
1902 4
1904 6
1905 4
1906 3
1907 7
1908 4
1909 5
1910 10
1911 10
1912 9
1913 17
1914 18
1915 10
1916 9
1917 2
1918 7
1919 10
1920 4
1921 5
1922 4
1923 13
1924 11
1925 8
1926 11
1927 13
1928 12
1929 10
1930 7
1931 15
1932 18
1933 6
1934 12
1935 13
1936 12
1937 15
1938 16
1939 19
1940 32
1941 25
1942 23
1943 25
1944 164
1945 10952
1946 35953
1947 43887
1948 46844
1949 41015
1950 61904
1951 73780
1952 74026
1953 73216
1954 70406
1955 73609
1956 72834
1957 77110
1958 75319
1959 74435
1960 73594
1961 79064
1962 85245
1963 92047
1964 99797
1965 109054
1966 107434
1967 112601
1968 118596
1969 119714
1970 119571
1971 123302
1972 126952
1973 129865
1974 134724
1975 144473
1976 149182
1977 156523
1978 166166
1979 175366
1980 175959
1981 179299
1982 187624
1983 200320
1984 211467
1985 221331
1986 228681
1987 242050
1988 255069
1989 270077
1990 277661
1991 276500
1992 279931
1993 289435
1994 298083
1995 308435
1996 317785
1997 329372
1998 342223
1999 354268
2000 370999
2001 384077
2002 398245
2003 422567
2004 449962
2005 488063
2006 520251
2007 548262
2008 579583
2009 605350
2010 647193
2011 697333
2012 735784
2013 779874
2014 805246
2015 824718
2016 820142
2017 823534
2018 839937
2019 878236
2020 1001390
2021 1050774
2022 901241
2023 69319
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Search Results

22,428,293 results
Results by year
Filters applied: . Clear all Quoted phrases not found in phrase index: "Amyloid Beta Peptides Genetics Metabolism", "Dna Damage Drug Effects Genetics", "Dna Repair Drug Effects Genetics", "Mitochondrial Genetics Metabolism", "Neuroblastoma Genetics Metabolism", "Oxidative Stress Drug Effects Genetics", "Peptide Fragments Genetics Metabolism"
Page 1
Oxidative stress and male infertility.
Bisht S, Faiq M, Tolahunase M, Dada R. Bisht S, et al. Nat Rev Urol. 2017 Aug;14(8):470-485. doi: 10.1038/nrurol.2017.69. Epub 2017 May 16. Nat Rev Urol. 2017. PMID: 28508879 Review.
DNA damage, largely owing to oxidative stress, is a leading cause of defective sperm function. ...Antioxidant regimens and lifestyle modifications could both be plausible therapeutic approaches that enable the burden of oxidative-stress-i …
DNA damage, largely owing to oxidative stress, is a leading cause of defective sperm function. ...Antioxidant re …
Enhancing mitochondrial proteostasis reduces amyloid-β proteotoxicity.
Sorrentino V, Romani M, Mouchiroud L, Beck JS, Zhang H, D'Amico D, Moullan N, Potenza F, Schmid AW, Rietsch S, Counts SE, Auwerx J. Sorrentino V, et al. Nature. 2017 Dec 14;552(7684):187-193. doi: 10.1038/nature25143. Epub 2017 Dec 6. Nature. 2017. PMID: 29211722 Free PMC article.
Alzheimer's disease is a common and devastating disease characterized by aggregation of the amyloid-beta peptide. ...Our data support the relevance of enhancing mitochondrial proteostasis to delay amyloid-beta proteot …
Alzheimer's disease is a common and devastating disease characterized by aggregation of the amyloid-beta …
Alzheimer's disease pathology propagation by exosomes containing toxic amyloid-beta oligomers.
Sardar Sinha M, Ansell-Schultz A, Civitelli L, Hildesjö C, Larsson M, Lannfelt L, Ingelsson M, Hallbeck M. Sardar Sinha M, et al. Acta Neuropathol. 2018 Jul;136(1):41-56. doi: 10.1007/s00401-018-1868-1. Epub 2018 Jun 13. Acta Neuropathol. 2018. PMID: 29934873 Free PMC article.
The gradual deterioration of cognitive functions in Alzheimer's disease is paralleled by a hierarchical progression of amyloid-beta and tau brain pathology. ...Here we show that small extracellular vesicles, exosomes, from Alzheimer patients' br …
The gradual deterioration of cognitive functions in Alzheimer's disease is paralleled by a hierarchical progression of amyl …
Redox proteomics and amyloid β-peptide: insights into Alzheimer disease.
Butterfield DA, Boyd-Kimball D. Butterfield DA, et al. J Neurochem. 2019 Nov;151(4):459-487. doi: 10.1111/jnc.14589. Epub 2018 Nov 27. J Neurochem. 2019. PMID: 30216447 Free PMC article. Review.
Amyloid beta-peptide (1-42) [Abeta(1-42)], a major component of senile plaques, is neurotoxic and induces oxidative stress in vitro and in vivo. ...These redox proteomics studies indicate that Abeta(1-42)-mediated oxidative stress …
Amyloid beta-peptide (1-42) [Abeta(1-42)], a major component of senile plaques, is neurotoxic and induces oxidative …
Mitochondrial Membrane Potential Influences Amyloid-β Protein Precursor Localization and Amyloid-β Secretion.
Wilkins HM, Troutwine BR, Menta BW, Manley SJ, Strope TA, Lysaker CR, Swerdlow RH. Wilkins HM, et al. J Alzheimers Dis. 2022;85(1):381-394. doi: 10.3233/JAD-215280. J Alzheimers Dis. 2022. PMID: 34806611 Free PMC article.
BACKGROUND: Amyloid-beta (Abeta), which derives from the amyloid-beta protein precursor (AbetaPP), forms plaques and serves as a fluid biomarker in Alzheimer's disease (AD). ...Mitochondrial AbetaPP and cell Abeta secretion …
BACKGROUND: Amyloid-beta (Abeta), which derives from the amyloid-beta protein precursor (AbetaPP), forms plaques …
Oral Collagen Drink for Antiaging: Antioxidation, Facilitation of the Increase of Collagen Synthesis, and Improvement of Protein Folding and DNA Repair in Human Skin Fibroblasts.
Lin P, Hua N, Hsu YC, Kan KW, Chen JH, Lin YH, Lin YH, Kuan CM. Lin P, et al. Oxid Med Cell Longev. 2020 May 11;2020:8031795. doi: 10.1155/2020/8031795. eCollection 2020. Oxid Med Cell Longev. 2020. PMID: 32454944 Free PMC article.
The results show that the collagen drink could perform the compact antiaging effects on ROS inhibition, the facilitation of the synthesis of extracellular matrix (ECM) proteins, the increase of mitochondrial activity, and improvement of the gene expression …
The results show that the collagen drink could perform the compact antiaging effects on ROS inhibition, the facilitation of the synth …
Transcriptomic and epigenomic landscapes of Alzheimer's disease evidence mitochondrial-related pathways.
Marmolejo-Garza A, Medeiros-Furquim T, Rao R, Eggen BJL, Boddeke E, Dolga AM. Marmolejo-Garza A, et al. Biochim Biophys Acta Mol Cell Res. 2022 Oct;1869(10):119326. doi: 10.1016/j.bbamcr.2022.119326. Epub 2022 Jul 14. Biochim Biophys Acta Mol Cell Res. 2022. PMID: 35839870 Free article. Review.
In addition to these hallmark-targeted approaches, several clinical trials focus on other AD pathological processes, such as inflammation, mitochondrial dysfunction, and oxidative stress. Mitochondria and mitochondrial-related mechanisms have be …
In addition to these hallmark-targeted approaches, several clinical trials focus on other AD pathological processes, such as inflammation, …
Oxidatively induced DNA damage and its repair in cancer.
Dizdaroglu M. Dizdaroglu M. Mutat Res Rev Mutat Res. 2015 Jan-Mar;763:212-45. doi: 10.1016/j.mrrev.2014.11.002. Epub 2014 Nov 25. Mutat Res Rev Mutat Res. 2015. PMID: 25795122 Review.
DNA lesions resulting from this type of damage are mutagenic and cytotoxic and, if not repaired, can cause genetic instability that may lead to disease processes including carcinogenesis. ...Mutations and polymorphisms also occur in DNA repai …
DNA lesions resulting from this type of damage are mutagenic and cytotoxic and, if not repaired, can cause genetic inst …
Mitochondrial reactive oxygen species cause major oxidative mitochondrial DNA damages and repair pathways.
Huang Z, Chen Y, Zhang Y. Huang Z, et al. J Biosci. 2020;45:84. J Biosci. 2020. PMID: 32661211 Free article. Review.
Among mitochondrial DNA repair pathways, the base excision repair pathway has been extensively characterized to remove some of oxidative damages in mtDNA as efficiently as the nuclear base excision repair. ...DNA damages caused by …
Among mitochondrial DNA repair pathways, the base excision repair pathway has been extensively characterized to …
Mitochondrial Disruption by Amyloid Beta 42 Identified by Proteomics and Pathway Mapping.
Sinclair P, Baranova A, Kabbani N. Sinclair P, et al. Cells. 2021 Sep 10;10(9):2380. doi: 10.3390/cells10092380. Cells. 2021. PMID: 34572029 Free PMC article.
Alzheimer's disease (AD) is marked by chronic neurodegeneration associated with the occurrence of plaques containing amyloid beta (Abeta) proteins in various parts of the human brain. ...Our results underscore a role for Abeta(42) in disrupting proteom …
Alzheimer's disease (AD) is marked by chronic neurodegeneration associated with the occurrence of plaques containing amyloi …
22,428,293 results
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