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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 2
1947 5
1963 1
1964 34
1965 133
1966 269
1967 274
1968 318
1969 423
1970 359
1971 376
1972 426
1973 381
1974 373
1975 356
1976 324
1977 231
1978 248
1979 254
1980 254
1981 201
1982 256
1983 223
1984 239
1985 242
1986 200
1987 191
1988 205
1989 182
1990 216
1991 215
1992 225
1993 233
1994 253
1995 274
1996 244
1997 251
1998 266
1999 319
2000 300
2001 364
2002 360
2003 373
2004 397
2005 367
2006 419
2007 430
2008 416
2009 421
2010 449
2011 501
2012 476
2013 492
2014 467
2015 477
2016 430
2017 421
2018 394
2019 213
2020 5
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16,779 results
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Page 1
Branched-Chain Amino Acids.
Yamamoto K, et al. Adv Biochem Eng Biotechnol 2017 - Review. PMID 27872960
Branched-chain amino acids (BCAAs), viz., L-isoleucine, L-leucine, and L-valine, are essential amino acids that cannot be synthesized in higher organisms and are important nutrition for humans as well as livestock. ...
Branched-chain amino acids (BCAAs), viz., L-isoleucine, L-leucine, and L-valine, are essential amino acids that …
Filling gaps in bacterial amino acid biosynthesis pathways with high-throughput genetics.
Price MN, et al. PLoS Genet 2018. PMID 29324779 Free PMC article.
For many bacteria with sequenced genomes, we do not understand how they synthesize some amino acids. This makes it challenging to reconstruct their metabolism, and has led to speculation that bacteria might be cross-feeding amino acids. ...Our results suggest that most free-living bacteria can likely make all 20 amino acids and illustrate how high-throughput genetics can uncover previously-unknown amino acid biosynthesis genes....
For many bacteria with sequenced genomes, we do not understand how they synthesize some amino acids. This makes it challenging …
N-Alkyl-α-amino acids in Nature and their biocatalytic preparation.
Hyslop JF, et al. J Biotechnol 2019 - Review. PMID 30690098
N-Alkylated-α-amino acids are useful building blocks for the pharmaceutical and fine chemical industries. Enantioselective methods of N-alkylated-α-amino acid synthesis are therefore highly valuable and widely investigated. ...Several enzyme classes that can be used to access chiral N-alkylated-α-amino acids and their substrate selectivities are detailed....
N-Alkylated-α-amino acids are useful building blocks for the pharmaceutical and fine chemical industries. Enantioselective met …
Cyanobacteria as efficient producers of mycosporine-like amino acids.
Jain S, et al. J Basic Microbiol 2017 - Review. PMID 28543536
Mycosporine-like amino acids are the most common group of transparent ultraviolet radiation absorbing intracellular secondary metabolites. ...In the last 30 years, scientists have investigated various cyanobacteria for novel mycosporine-like amino acids, applying different induction techniques. ...
Mycosporine-like amino acids are the most common group of transparent ultraviolet radiation absorbing intracellular secondary …
Amino-group carrier-protein-mediated secondary metabolite biosynthesis in Streptomyces.
Hasebe F, et al. Nat Chem Biol 2016. PMID 28288097
Amino-group carrier proteins (AmCPs) mediate the biosynthesis of lysine and arginine in some bacteria and archaea. Here we demonstrate that an uncharacterized AmCP-mediated biosynthetic system functions to biosynthesize the previously uncharacterized and nonproteinogenic amino acid (2S,6R)-diamino-(5R,7)-dihydroxy-heptanoic acid (DADH) in Streptomyces sp. ...As the AmCP-mediated machinery for DADH biosynthesis is widely distributed in bacteria, further analysis of uncharacterized AmCP-containing gene clusters will lead to the discovery of novel bioactive compounds and novel biosynthetic enzymes....
Amino-group carrier proteins (AmCPs) mediate the biosynthesis of lysine and arginine in some bacteria and archaea. Here we dem
Synthesis and chirality of amino acids under interstellar conditions.
Giri C, et al. Top Curr Chem 2013 - Review. PMID 22976459
Amino acids are the fundamental building blocks of proteins, the biomolecules that provide cellular structure and function in all living organisms. ...In order to trace the chemical evolution of life, an appreciation of the synthetic and evolutional origins of the first chiral amino acids must first be gained. ...
Amino acids are the fundamental building blocks of proteins, the biomolecules that provide cellular structure and function in
The shikimate pathway and aromatic amino Acid biosynthesis in plants.
Maeda H and Dudareva N. Annu Rev Plant Biol 2012 - Review. PMID 22554242
L-tryptophan, L-phenylalanine, and L-tyrosine are aromatic amino acids (AAAs) that are used for the synthesis of proteins and that in plants also serve as precursors of numerous natural products, such as pigments, alkaloids, hormones, and cell wall components. ...
L-tryptophan, L-phenylalanine, and L-tyrosine are aromatic amino acids (AAAs) that are used for the synthesis of proteins and …
Renal metabolism of amino acids: its role in interorgan amino acid exchange.
van de Poll MC, et al. Am J Clin Nutr 2004 - Review. PMID 14749222
The kidneys play a role in the synthesis and interorgan exchange of several amino acids. The quantitative importance of renal amino acid metabolism in the body is not, however, clear. ...The kidneys play an important role in the interorgan exchange of amino acids. Quantitatively, for several important amino acids, the kidneys are as important as the gut in intermediary metabolism. ...
The kidneys play a role in the synthesis and interorgan exchange of several amino acids. The quantitative importance of renal …
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