Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1789 3
1790 1
1791 1
1792 2
1796 1
1797 5
1799 13
1800 10
1801 2
1802 2
1803 5
1804 5
1805 3
1806 10
1807 3
1808 1
1809 7
1810 6
1811 10
1812 5
1813 3
1814 9
1815 4
1816 10
1817 16
1818 20
1819 9
1820 41
1821 65
1822 58
1823 58
1824 49
1825 49
1826 84
1827 48
1828 76
1829 70
1830 76
1831 68
1832 57
1833 65
1834 65
1835 49
1836 85
1837 100
1838 111
1839 114
1840 119
1841 143
1842 139
1843 144
1844 188
1845 219
1846 227
1847 204
1848 84
1849 104
1850 98
1851 100
1852 114
1853 155
1854 69
1855 99
1856 70
1857 84
1858 88
1859 86
1860 70
1861 73
1862 60
1863 65
1864 54
1865 40
1866 53
1867 44
1868 58
1869 58
1870 57
1871 58
1872 70
1873 56
1874 90
1875 103
1876 117
1877 108
1878 66
1879 54
1880 33
1881 44
1882 37
1883 28
1884 34
1885 70
1886 39
1887 41
1888 35
1889 52
1890 40
1891 42
1892 42
1893 42
1894 46
1895 52
1896 64
1897 71
1898 74
1899 54
1900 61
1901 39
1902 48
1903 40
1904 54
1905 53
1906 51
1907 46
1908 50
1909 80
1910 54
1911 84
1912 82
1913 78
1914 94
1915 87
1916 105
1917 74
1918 77
1919 82
1920 78
1921 94
1922 83
1923 74
1924 113
1925 120
1926 122
1927 145
1928 125
1929 134
1930 137
1931 148
1932 138
1933 128
1934 142
1935 189
1936 170
1937 172
1938 194
1939 158
1940 149
1941 160
1942 125
1943 123
1944 178
1945 1845
1946 6154
1947 7439
1948 6898
1949 6196
1950 9137
1951 10810
1952 10705
1953 11718
1954 12262
1955 12574
1956 13198
1957 14300
1958 14746
1959 15311
1960 16155
1961 17628
1962 18769
1963 26777
1964 34957
1965 44197
1966 52408
1967 58519
1968 63853
1969 69146
1970 70437
1971 75847
1972 81099
1973 84916
1974 88466
1975 94196
1976 94357
1977 96016
1978 99694
1979 105211
1980 108993
1981 111222
1982 115575
1983 121718
1984 127413
1985 132583
1986 140164
1987 151204
1988 168210
1989 182149
1990 191577
1991 195896
1992 202310
1993 209215
1994 220751
1995 227324
1996 233154
1997 238439
1998 247468
1999 256020
2000 275435
2001 286645
2002 298025
2003 317551
2004 345110
2005 376011
2006 404550
2007 423413
2008 444753
2009 464455
2010 498045
2011 537574
2012 575439
2013 603525
2014 630874
2015 650917
2016 654836
2017 668196
2018 692986
2019 719216
2020 799953
2021 858543
2022 833695
2023 796074
2024 595021
2025 371

Text availability

Article attribute

Article type

Publication date

Search Results

17,291,630 results

Results by year

Filters applied: . Clear all
Quoted phrases not found in phrase index: "Polyene Antibiotic Agent", "Tetrapyrrole Derivative"
Page 1
Semisynthetic Amides of Polyene Antibiotic Natamycin.
Tevyashova AN, Efimova SS, Alexandrov AI, Ghazy ESMO, Bychkova EN, Solovieva SE, Zatonsky GB, Grammatikova NE, Dezhenkova LG, Pereverzeva ER, Isakova EB, Ostroumova OS, Omelchuk OA, Muravieva VV, Krotova MM, Priputnevich TV, Shchekotikhin AE. Tevyashova AN, et al. ACS Infect Dis. 2023 Jan 13;9(1):42-55. doi: 10.1021/acsinfecdis.2c00237. Epub 2022 Dec 23. ACS Infect Dis. 2023. PMID: 36563312
Natamycin is a macrolide polyene antibiotic, characterized by a potent broad spectrum antifungal activity and low toxicity. ...Toxicity for mammalian cells was assayed by monitoring antiproliferative activity against human postnatal fibroblasts (HPF) and h …
Natamycin is a macrolide polyene antibiotic, characterized by a potent broad spectrum antifungal activity and low toxicity. .. …
Immunosuppressive drugs.
Collier SJ. Collier SJ. Curr Opin Immunol. 1989-1990;2(6):854-8. doi: 10.1016/0952-7915(89)90169-6. Curr Opin Immunol. 1989. PMID: 2484794 Review. No abstract available.
Polyenic Antibiotics and Other Antifungal Compounds Produced by Hemolytic Streptomyces Species.
Bobek J, Filipová E, Bergman N, Čihák M, Petříček M, Lara AC, Kristufek V, Megyes M, Wurzer T, Chroňáková A, Petříčková K. Bobek J, et al. Int J Mol Sci. 2022 Nov 30;23(23):15045. doi: 10.3390/ijms232315045. Int J Mol Sci. 2022. PMID: 36499372 Free PMC article. Review.
An additional human-associated S. sp. TR1341 served as a control. Mass spectrometry analysis suggested synthesis of polyene molecules responsible for the hemolysis: candicidins, filipins, strevertene A, tetrafungin, and tetrin A, as well as four novel polyene …
An additional human-associated S. sp. TR1341 served as a control. Mass spectrometry analysis suggested synthesis of polyene mo …
Conformational diseases and structure-toxicity relationships: lessons from prion-derived peptides.
Ronga L, Palladino P, Costantini S, Facchiano A, Ruvo M, Benedetti E, Ragone R, Rossi F. Ronga L, et al. Curr Protein Pept Sci. 2007 Feb;8(1):83-90. doi: 10.2174/138920307779941505. Curr Protein Pept Sci. 2007. PMID: 17305562 Review.
Available evidence suggests that this protein is essential for neuronal integrity in the brain, possibly with a role in copper metabolism and cellular response to oxidative stress. In prion diseases, the benign cellular form of the protein is converted …
Available evidence suggests that this protein is essential for neuronal integrity in the brain, possibly with a role in copper met …
Elfamycins: inhibitors of elongation factor-Tu.
Prezioso SM, Brown NE, Goldberg JB. Prezioso SM, et al. Mol Microbiol. 2017 Oct;106(1):22-34. doi: 10.1111/mmi.13750. Epub 2017 Aug 9. Mol Microbiol. 2017. PMID: 28710887 Free PMC article. Review.
For the most part, the utility of these compounds has been as laboratory tools for the study of EF-Tu and the ribosome, as their poor pharmacokinetic profile and solubility has prevented implementation as therapeutic agents. However, due to the slowing of the antibiotic …
For the most part, the utility of these compounds has been as laboratory tools for the study of EF-Tu and the ribosome, as their poor pharma …
Polyene antibiotic biosynthesis gene clusters.
Aparicio JF, Caffrey P, Gil JA, Zotchev SB. Aparicio JF, et al. Appl Microbiol Biotechnol. 2003 May;61(3):179-88. doi: 10.1007/s00253-002-1183-5. Epub 2002 Dec 18. Appl Microbiol Biotechnol. 2003. PMID: 12698274 Review.
This body of work also provides insights into the enzymes catalysing the unusual post-polyketide modifications, and the genes regulating antibiotic biosynthesis. The sequences also provide clues about the evolutionary origins of polyene biosynthetic genes. Successfu …
This body of work also provides insights into the enzymes catalysing the unusual post-polyketide modifications, and the genes regulating …
Polyene antibiotic - sterol interaction.
Norman AW, Spielvogel AM, Wong RG. Norman AW, et al. Adv Lipid Res. 1976;14:127-70. Adv Lipid Res. 1976. PMID: 769498 Review. No abstract available.
Polyene macrolide biosynthesis in streptomycetes and related bacteria: recent advances from genome sequencing and experimental studies.
Caffrey P, De Poire E, Sheehan J, Sweeney P. Caffrey P, et al. Appl Microbiol Biotechnol. 2016 May;100(9):3893-908. doi: 10.1007/s00253-016-7474-z. Epub 2016 Mar 29. Appl Microbiol Biotechnol. 2016. PMID: 27023916 Review.
The polyene macrolide group includes important antifungal drugs, to which resistance does not arise readily. Chemical and biological methods have been used in attempts to make polyene antibiotics with fewer toxic side effects. Genome sequencing of producer or …
The polyene macrolide group includes important antifungal drugs, to which resistance does not arise readily. Chemical and biological …
Supramolecular Antibacterial Materials for Combatting Antibiotic Resistance.
Li X, Bai H, Yang Y, Yoon J, Wang S, Zhang X. Li X, et al. Adv Mater. 2019 Feb;31(5):e1805092. doi: 10.1002/adma.201805092. Epub 2018 Dec 7. Adv Mater. 2019. PMID: 30536445 Review.
Antibiotic-resistant bacteria have emerged as a severe threat to human health. As effective antibacterial therapies, supramolecular materials display unprecedented advantages because of the flexible and tunable nature of their noncovalent interactions with biomolecu …
Antibiotic-resistant bacteria have emerged as a severe threat to human health. As effective antibacterial therapies, supramole …
Biological activity of polyene antibiotics.
Hammond SM. Hammond SM. Prog Med Chem. 1977;14:105-79. doi: 10.1016/s0079-6468(08)70148-6. Prog Med Chem. 1977. PMID: 345355 Review. No abstract available.
17,291,630 results
You have reached the last available page of results. Please see the User Guide for more information.