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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1954 1
1955 1
1956 1
1958 2
1959 3
1960 9
1961 11
1962 24
1963 79
1964 142
1965 103
1966 116
1967 191
1968 228
1969 255
1970 279
1971 271
1972 303
1973 285
1974 365
1975 416
1976 418
1977 377
1978 405
1979 499
1980 462
1981 491
1982 489
1983 531
1984 745
1985 884
1986 969
1987 1039
1988 1224
1989 1557
1990 1806
1991 1896
1992 1591
1993 1043
1994 1117
1995 1164
1996 1061
1997 1083
1998 1018
1999 1020
2000 1108
2001 1098
2002 901
2003 1004
2004 1040
2005 1121
2006 1116
2007 1171
2008 1155
2009 1094
2010 1258
2011 1366
2012 1347
2013 1401
2014 1335
2015 1250
2016 1135
2017 1045
2018 892
2019 463
2020 4
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46,134 results
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Page 1
Cellular Stress Associated with Aneuploidy.
Zhu J, et al. Dev Cell 2018 - Review. PMID 29486194 Free PMC article.
Here, we review the current understanding about the cellular stress states that may result from aneuploidy. The topics of aneuploidy-induced proteotoxic, metabolic, replication, and mitotic stress are assessed in the context of the gene dosage imbalance observed in aneuploid cells. We also highlight emerging findings related to the downstream effects of aneuploidy-induced cellular stress on the immune surveillance against aneuploid cells....
Here, we review the current understanding about the cellular stress states that may result from aneuploidy. The topics of aneuploi
[Relationship between the choroid plexus cyst and the aneuploidy].
Nan Y, et al. Zhonghua Yi Xue Za Zhi 2018. PMID 30392253 Chinese.
Objective: Using the method of the ultrasound and the noninvasive DNA to find the relationship between the choroid plexus cyst and the aneuploidy, and to provide the meaningful data for prenatal consultant. ...When the aneuploidy had diagnosed definitely, induced labor had been taken. One case was found to be the aneuploidy in the control group, and took the induced labor. ...
Objective: Using the method of the ultrasound and the noninvasive DNA to find the relationship between the choroid plexus cyst and the an
The impact of aneuploidy on cellular homeostasis.
Newman DL, et al. Free Radic Res 2019 - Review. PMID 31117839
In this review we briefly discuss how instability comes about, then focus on the impact of gain or loss of DNA (aneuploidy) on oxidative stress. We discuss several mechanisms that lead from aneuploidy to the production of reactive oxygen species, including the effects on protein complex stoichiometry, endoplasmic reticulum stress and metabolic disruption. ...
In this review we briefly discuss how instability comes about, then focus on the impact of gain or loss of DNA (aneuploidy) on oxidat …
A review of trisomy X (47,XXX)
Tartaglia NR, et al. Orphanet J Rare Dis 2010 - Review. PMID 20459843 Free PMC article.
Practice Bulletin No. 162: Prenatal Diagnostic Testing for Genetic Disorders
American College of Obstetricians and Gynecologists’ Committee on Practice Bulletins—Obstetrics , et al. Obstet Gynecol 2016. PMID 26938573
For information regarding screening for fetal aneuploidy, refer to Practice Bulletin No. 163, Screening for Fetal Aneuploidy....
For information regarding screening for fetal aneuploidy, refer to Practice Bulletin No. 163, Screening for Fetal Aneuploidy.. …
Meiosis and maternal aging: insights from aneuploid oocytes and trisomy births
Herbert M, et al. Cold Spring Harb Perspect Biol 2015 - Review. PMID 25833844 Free PMC article.
Extending this period beyond ∼35 years greatly increases the risk of aneuploidy in human oocytes, resulting in a dramatic increase in infertility, miscarriage, and birth defects, most notably trisomy 21. ...Consistent with this, premature loss of centromeric cohesion is a major source of aneuploidy in oocytes from older women. Here, we propose a mechanistic framework to reconcile data from genetic studies on human trisomy and oocytes with recent advances in our understanding of the molecular mechanisms of chromosome segregation during meiosis in model organisms....
Extending this period beyond ∼35 years greatly increases the risk of aneuploidy in human oocytes, resulting in a dramatic increase in …
Expanding the indications for cell-free DNA in the maternal circulation: clinical considerations and implications
Di Renzo GC, et al. Am J Obstet Gynecol 2019 - Review. PMID 30639383
Noninvasive prenatal testing for fetal aneuploidy using cell-free DNA has been widely integrated into routine obstetrical care. ...
Noninvasive prenatal testing for fetal aneuploidy using cell-free DNA has been widely integrated into routine obstetrical care. ...
Unique features of the transcriptional response to model aneuploidy in human cells.
Dürrbaum M, et al. BMC Genomics 2014. PMID 24548329 Free PMC article.
BACKGROUND: Aneuploidy, a karyotype deviating from multiples of a haploid chromosome set, affects the physiology of eukaryotes. ...There are many different types and origins of aneuploidy, but whether there is a uniform cellular response to aneuploidy in human cells has not been addressed so far. ...
BACKGROUND: Aneuploidy, a karyotype deviating from multiples of a haploid chromosome set, affects the physiology of eukaryotes. ...Th …
46,134 results
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