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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1781 37
1782 18
1783 22
1784 27
1785 43
1786 60
1787 43
1788 33
1789 32
1790 44
1791 19
1792 33
1793 17
1794 18
1795 13
1796 14
1797 59
1798 15
1799 291
1800 377
1801 360
1802 283
1803 269
1804 289
1805 314
1806 282
1807 295
1808 289
1809 265
1810 267
1811 322
1812 238
1813 265
1814 285
1815 222
1816 315
1817 288
1818 303
1819 225
1820 213
1821 270
1822 247
1823 291
1824 269
1825 262
1826 385
1827 326
1828 467
1829 645
1830 569
1831 627
1832 313
1833 293
1834 287
1835 305
1836 271
1837 350
1838 484
1839 546
1840 695
1841 1154
1842 1488
1843 1121
1844 1251
1845 1278
1846 1404
1847 1368
1848 1203
1849 1208
1850 1126
1851 1228
1852 1312
1853 1558
1854 1306
1855 1587
1856 1588
1857 1488
1858 1542
1859 1562
1860 1632
1861 1275
1862 1112
1863 995
1864 1138
1865 1151
1866 1477
1867 1723
1868 1813
1869 1909
1870 1810
1871 2238
1872 2242
1873 2313
1874 2508
1875 2402
1876 2095
1877 2180
1878 2455
1879 2399
1880 2646
1881 3149
1882 2742
1883 3127
1884 3049
1885 3337
1886 3291
1887 3965
1888 4002
1889 4194
1890 4024
1891 3578
1892 4093
1893 4369
1894 3801
1895 4130
1896 4412
1897 4688
1898 4631
1899 4169
1900 3785
1901 3886
1902 3967
1903 3910
1904 4059
1905 4067
1906 3872
1907 4324
1908 4514
1909 4766
1910 4885
1911 5098
1912 5016
1913 5248
1914 5243
1915 4701
1916 4569
1917 4323
1918 4596
1919 4717
1920 5037
1921 4703
1922 4192
1923 4519
1924 4945
1925 5058
1926 5397
1927 5945
1928 5537
1929 5798
1930 5694
1931 5572
1932 5629
1933 5695
1934 5577
1935 5736
1936 5448
1937 5378
1938 5829
1939 5615
1940 5024
1941 4865
1942 4800
1943 4543
1944 4764
1945 20490
1946 53906
1947 65002
1948 70707
1949 62803
1950 85755
1951 103743
1952 108054
1953 108915
1954 105914
1955 108545
1956 107007
1957 111522
1958 109458
1959 109962
1960 112139
1961 120102
1962 125637
1963 141521
1964 162087
1965 176645
1966 179747
1967 191507
1968 207852
1969 215049
1970 218961
1971 222912
1972 227524
1973 230657
1974 234537
1975 248251
1976 250486
1977 250307
1978 258578
1979 265845
1980 267561
1981 271817
1982 283349
1983 294928
1984 302900
1985 319136
1986 331577
1987 347464
1988 363678
1989 377739
1990 382792
1991 380625
1992 382219
1993 390096
1994 401645
1995 410947
1996 420977
1997 418749
1998 436404
1999 453681
2000 490526
2001 503142
2002 520936
2003 548612
2004 591652
2005 650324
2006 695376
2007 733277
2008 780295
2009 819049
2010 881309
2011 955636
2012 1021526
2013 1072527
2014 1124150
2015 1164670
2016 1195501
2017 1215372
2018 1257668
2019 1313430
2020 1495407
2021 1633057
2022 1628297
2023 1532252
2024 515409
2025 2
2026 1

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34,688,798 results

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Page 1
Handling Metalloproteinases.
Fridrich S, Karmilin K, Stöcker W. Fridrich S, et al. Curr Protoc Protein Sci. 2016 Feb 2;83:21.16.1-21.16.20. doi: 10.1002/0471140864.ps2116s83. Curr Protoc Protein Sci. 2016. PMID: 26836407 Review.
The zinc ion is most often complexed by imidazole nitrogens of histidine side chains. This arrangement suggests that the physiological pH optimum of most metalloproteinases is in the neutral range. ...Moreover, the catalytic metal can be displaced by a …
The zinc ion is most often complexed by imidazole nitrogens of histidine side chains. This arrangement suggests that the ph
Angiogenin and Copper Crossing in Wound Healing.
Cucci LM, Satriano C, Marzo T, La Mendola D. Cucci LM, et al. Int J Mol Sci. 2021 Oct 2;22(19):10704. doi: 10.3390/ijms221910704. Int J Mol Sci. 2021. PMID: 34639045 Free PMC article. Review.
Angiogenesis plays a key role in the wound healing process, involving the migration, growth, and differentiation of endothelial cells. Angiogenesis is controlled by a strict balance of different factors, and among these, the angiogenin protein plays a relevant role. …
Angiogenesis plays a key role in the wound healing process, involving the migration, growth, and differentiation of endothelial ce
Divalent metal ion binding to Staphylococcus aureus FeoB transporter regions.
Dzyhovskyi V, Stokowa-Sołtys K. Dzyhovskyi V, et al. J Inorg Biochem. 2023 Jul;244:112203. doi: 10.1016/j.jinorgbio.2023.112203. Epub 2023 Mar 29. J Inorg Biochem. 2023. PMID: 37018851 Free article.
Transition metal ions such as iron, copper, zinc, manganese or, nickel are essential in many biological processes. ...Moreover, comparing preferences of all ligands towards different metal ions, copper(II) complexes are the most stable on …
Transition metal ions such as iron, copper, zinc, manganese or, nickel are essential in many biological processes. ...Moreover …
Structural Consequences of Copper Binding to the Prion Protein.
Salzano G, Giachin G, Legname G. Salzano G, et al. Cells. 2019 Jul 25;8(8):770. doi: 10.3390/cells8080770. Cells. 2019. PMID: 31349611 Free PMC article. Review.
The most relevant function of PrP(C) is its ability to bind copper ions through its flexible N-terminal moiety. This review includes an overview of the structure and function of PrP(C) with a focus on its ability to bind copper ions. The state-of-the-a …
The most relevant function of PrP(C) is its ability to bind copper ions through its flexible N-terminal moiety. This review in …
Copper(II) Complexes of Pyridine-2,6-dicarboxamide Ligands with High SOD Activity.
Diószegi R, Bonczidai-Kelemen D, Bényei AC, May NV, Fábián I, Lihi N. Diószegi R, et al. Inorg Chem. 2022 Jan 31;61(4):2319-2332. doi: 10.1021/acs.inorgchem.1c03728. Epub 2022 Jan 14. Inorg Chem. 2022. PMID: 35029102
Although the coordination mode is the same for the two systems, the tyrosine containing counterpart exhibits increased copper(II) binding affinity, which is most likely due to the presence of the aromatic moiety of the side chains. Both copper( …
Although the coordination mode is the same for the two systems, the tyrosine containing counterpart exhibits increased copper(II
Metal-Peptide Complexes to Study Neurodegenerative Diseases.
Mital M, Sęk JP, Ziora ZM. Mital M, et al. Methods Mol Biol. 2020;2103:323-336. doi: 10.1007/978-1-0716-0227-0_22. Methods Mol Biol. 2020. PMID: 31879936
Therefore, a deep understanding of Cu(II)-binding properties to metal ions carriers, together with the knowledge about how they can interact with other copper-binding partners, e.g., amyloid-beta (Abeta), is required to assess their relevance to the br …
Therefore, a deep understanding of Cu(II)-binding properties to metal ions carriers, together with the knowledge about how the …
Copper(II)-Induced Restructuring of ZnuD, a Zinc(II) Transporter from Neisseria meningitidis.
Hecel A, Rowińska-Żyrek M, Kozłowski H. Hecel A, et al. Inorg Chem. 2019 May 6;58(9):5932-5942. doi: 10.1021/acs.inorgchem.9b00265. Epub 2019 Apr 15. Inorg Chem. 2019. PMID: 30986048
Copper(II) complexes with the studied ZnuD regions are thermodynamically more stable than the zinc(II) ones-Cu(II) complexes dominate in solution even in close to physiological ratios of the studied metal ions (a 10-fold excess of Zn(II) over Cu(II)).
Copper(II) complexes with the studied ZnuD regions are thermodynamically more stable than the zinc(II) ones-Cu(II) complexes d
Progress in the Development of Biosensors Based on Peptide-Copper Coordination Interaction.
Liu G, Xia N, Tian L, Sun Z, Liu L. Liu G, et al. Biosensors (Basel). 2022 Sep 30;12(10):809. doi: 10.3390/bios12100809. Biosensors (Basel). 2022. PMID: 36290946 Free PMC article. Review.
Copper ions, as the active centers of natural enzymes, play an important role in many physiological processes. ...The peptide-copper complexes exhibit the characteristics of low molecular weight, high tenability, and unique catalytic and photophysical
Copper ions, as the active centers of natural enzymes, play an important role in many physiological processes. ...The peptide-
Copper-induced spectroscopic and structural changes in short peptides derived from azurin.
Das D, Mitra S, Kumar R, Banerjee S, Koti Ainavarapu SR. Das D, et al. Arch Biochem Biophys. 2020 Jul 15;687:108388. doi: 10.1016/j.abb.2020.108388. Epub 2020 Apr 25. Arch Biochem Biophys. 2020. PMID: 32343975
Here, we report the copper-binding associated spectroscopic and structural properties of peptide loops (11 and 13 residues) from the copper-binding site of azurin. These peptides develop a beta-turn upon copper-binding with a 1:1 C …
Here, we report the copper-binding associated spectroscopic and structural properties of peptide loops (11 and 13 residues) fr …
Organogenesis and angiogenin.
Vallee BL, Riordan JF. Vallee BL, et al. Cell Mol Life Sci. 1997 Oct;53(10):803-15. doi: 10.1007/s000180050101. Cell Mol Life Sci. 1997. PMID: 9413551 Review.
It lacks one of the four disulphide loops of RNase A; instead, the corresponding residues form part of a cell binding region. Both the catalytic activity and cell binding site are essential for angiogenesis. Angiogenin binds to cell-surface acti …
It lacks one of the four disulphide loops of RNase A; instead, the corresponding residues form part of a cell binding region. …
34,688,798 results
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