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Anhedonia and Depressive Disorders.
Serretti A. Serretti A. Clin Psychopharmacol Neurosci. 2023 Aug 31;21(3):401-409. doi: 10.9758/cpn.23.1086. Clin Psychopharmacol Neurosci. 2023. PMID: 37424409 Free PMC article. Review.
Anhedonia is a core symptom of depression and of several psychiatric disorders. Anhedonia has however expanded from its original definition to encompass a spectrum of reward processing deficits that received much interest in the last decades. ...Its neurophysiologic …
Anhedonia is a core symptom of depression and of several psychiatric disorders. Anhedonia has however expanded from its origin …
Assessing anhedonia in depression: Potentials and pitfalls.
Rizvi SJ, Pizzagalli DA, Sproule BA, Kennedy SH. Rizvi SJ, et al. Neurosci Biobehav Rev. 2016 Jun;65:21-35. doi: 10.1016/j.neubiorev.2016.03.004. Epub 2016 Mar 6. Neurosci Biobehav Rev. 2016. PMID: 26959336 Free PMC article. Review.
The resurgence of interest in anhedonia within major depression has been fuelled by clinical trials demonstrating its utility in predicting antidepressant response as well as recent conceptualizations focused on the role and manifestation of anhedonia in depression. …
The resurgence of interest in anhedonia within major depression has been fuelled by clinical trials demonstrating its utility in pred …
Reconsidering anhedonia in depression: lessons from translational neuroscience.
Treadway MT, Zald DH. Treadway MT, et al. Neurosci Biobehav Rev. 2011 Jan;35(3):537-55. doi: 10.1016/j.neubiorev.2010.06.006. Epub 2010 Jul 11. Neurosci Biobehav Rev. 2011. PMID: 20603146 Free PMC article. Review.
Moreover, bridging the gap between preclinical and clinical models of anhedonia may require moving away from the conceptualization of anhedonia as a steady-state, mood-like phenomena. Consequently, we introduce the term "decisional anhedonia" to address the i …
Moreover, bridging the gap between preclinical and clinical models of anhedonia may require moving away from the conceptualization of …
Anhedonia and Suicide.
Auerbach RP, Pagliaccio D, Kirshenbaum JS. Auerbach RP, et al. Curr Top Behav Neurosci. 2022;58:443-464. doi: 10.1007/7854_2022_358. Curr Top Behav Neurosci. 2022. PMID: 35435645 Review.
Third, although anhedonia is not directly addressed in leading suicide theories, this review will provide potential inroads to explore anhedonia within diathesis-stress and interpersonal suicide frameworks. Last, novel approaches to treat anhedonia as a means …
Third, although anhedonia is not directly addressed in leading suicide theories, this review will provide potential inroads to explor …
The neurobiology of anhedonia and other reward-related deficits.
Der-Avakian A, Markou A. Der-Avakian A, et al. Trends Neurosci. 2012 Jan;35(1):68-77. doi: 10.1016/j.tins.2011.11.005. Epub 2011 Dec 15. Trends Neurosci. 2012. PMID: 22177980 Free PMC article. Review.
Anhedonia, or markedly diminished interest or pleasure, is a hallmark symptom of major depression, schizophrenia and other neuropsychiatric disorders. ...Here, we review the neural bases of the construct of anhedonia that reflects deficits in hedonic capacity and al …
Anhedonia, or markedly diminished interest or pleasure, is a hallmark symptom of major depression, schizophrenia and other neuropsych …
Anhedonia in Neurodegenerative Diseases.
Turner V, Husain M. Turner V, et al. Curr Top Behav Neurosci. 2022;58:255-277. doi: 10.1007/7854_2022_352. Curr Top Behav Neurosci. 2022. PMID: 35435648 Review.
Much of the research has been conducted in Parkinson's disease where it is evident that there are strong links between apathy (loss of motivation) and anhedonia, although the two syndromes can be dissociated. Intriguingly, drugs that improve apathy can also lead to amelior …
Much of the research has been conducted in Parkinson's disease where it is evident that there are strong links between apathy (loss of motiv …
Pharmacological interventions targeting anhedonia in patients with major depressive disorder: A systematic review.
Cao B, Zhu J, Zuckerman H, Rosenblat JD, Brietzke E, Pan Z, Subramanieapillai M, Park C, Lee Y, McIntyre RS. Cao B, et al. Prog Neuropsychopharmacol Biol Psychiatry. 2019 Jun 8;92:109-117. doi: 10.1016/j.pnpbp.2019.01.002. Epub 2019 Jan 3. Prog Neuropsychopharmacol Biol Psychiatry. 2019. PMID: 30611836
Anhedonia is defined as a diminished ability to experience interest or pleasure, and is a critical psychopathological dimension of major depressive disorder (MDD). ...Based on the available evidence, most antidepressants demonstrated beneficial effects on measures of an …
Anhedonia is defined as a diminished ability to experience interest or pleasure, and is a critical psychopathological dimension of ma …
Toward a Better Understanding of the Mechanisms and Pathophysiology of Anhedonia: Are We Ready for Translation?
Pizzagalli DA. Pizzagalli DA. Am J Psychiatry. 2022 Jul;179(7):458-469. doi: 10.1176/appi.ajp.20220423. Am J Psychiatry. 2022. PMID: 35775159 Free PMC article. Review.
Anhedonia-the loss of pleasure or lack of reactivity to pleasurable stimuli-remains a formidable treatment challenge across neuropsychiatric disorders. ...These include a need for 1) appropriately controlled clinical trials, especially those embracing an experimental thera …
Anhedonia-the loss of pleasure or lack of reactivity to pleasurable stimuli-remains a formidable treatment challenge across neuropsyc …
Treatment for Anhedonia: A Neuroscience Driven Approach.
Craske MG, Meuret AE, Ritz T, Treanor M, Dour HJ. Craske MG, et al. Depress Anxiety. 2016 Oct;33(10):927-938. doi: 10.1002/da.22490. Depress Anxiety. 2016. PMID: 27699943
Anhedonia is a predictor of poor long-term outcomes, including suicide, and poor treatment response. ...Second, we discuss the evidence linking anhedonia to biological, experiential, and behavioral deficits in the reward subsystems. ...
Anhedonia is a predictor of poor long-term outcomes, including suicide, and poor treatment response. ...Second, we discuss the eviden …
Understanding Anhedonia from a Genomic Perspective.
Bondy E, Bogdan R. Bondy E, et al. Curr Top Behav Neurosci. 2022;58:61-79. doi: 10.1007/7854_2021_293. Curr Top Behav Neurosci. 2022. PMID: 35152374 Free PMC article. Review.
Anhedonia, or the decreased ability to experience pleasure, is a cardinal symptom of major depression that commonly occurs within other forms of psychopathology. ...This has resulted in few and underpowered studies of anhedonia-related constructs that have largely f …
Anhedonia, or the decreased ability to experience pleasure, is a cardinal symptom of major depression that commonly occurs within oth …
6,831 results