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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 1
1947 1
1948 3
1949 1
1950 4
1951 150
1952 483
1953 673
1954 743
1955 745
1956 733
1957 869
1958 879
1959 367
1960 4
1961 8
1962 5
1963 19
1964 59
1965 973
1966 1648
1967 1830
1968 2133
1969 2329
1970 2213
1971 2354
1972 2152
1973 2325
1974 2216
1975 1679
1976 1611
1977 1612
1978 1662
1979 1957
1980 1756
1981 2058
1982 2410
1983 2408
1984 2631
1985 2675
1986 2691
1987 2676
1988 2710
1989 2974
1990 2922
1991 2947
1992 2975
1993 2929
1994 3041
1995 5088
1996 7179
1997 7973
1998 8790
1999 9228
2000 9458
2001 9879
2002 10326
2003 11208
2004 11575
2005 12491
2006 13770
2007 14260
2008 15022
2009 15830
2010 16872
2011 17766
2012 18746
2013 19154
2014 19690
2015 19746
2016 18914
2017 18827
2018 18423
2019 9184
2020 110
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387,309 results
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Page 1
Nonsurgical periodontal therapy
Drisko CH. Periodontol 2000 2001 - Review. PMID 11155183
More aggressive types of juvenile periodontitis or severe rapidly advancing adult periodontitis usually require a combination of surgical intervention in conjunction with systemic antibiotics and generally are not controlled with nonsurgical anti-infective therapy alone. ...Frequent re-evaluation and careful monitoring allows the practitioner the opportunity to intervene early in the disease state, to reverse or arrest the progression of periodontal disease with meticulous nonsurgical anti-infective therapy....
More aggressive types of juvenile periodontitis or severe rapidly advancing adult periodontitis usually require a combination of surgical in …
Empiric Antibiotics for Sepsis
Buckman SA, et al. Surg Infect (Larchmt) 2018 - Review. PMID 29341844
Selection of antimicrobial agents is based on a combination of patient factors, predicted infecting organism(s), and local microbial resistance patterns. ...
Selection of antimicrobial agents is based on a combination of patient factors, predicted infecting organism(s), and local microbial …
Current evidence on hospital antimicrobial stewardship objectives: a systematic review and meta-analysis
Schuts EC, et al. Lancet Infect Dis 2016 - Review. PMID 26947617
For the objectives empirical therapy according to guidelines, de-escalation of therapy, switch from intravenous to oral treatment, therapeutic drug monitoring, use of a list of restricted antibiotics, and bedside consultation the overall evidence showed significant benefits for one or more of the four outcomes. ...INTERPRETATION: Our findings of beneficial effects on outcomes with nine antimicrobial stewardship objectives suggest they can guide stewardship teams in their efforts to improve the quality of antibiotic use in hospitals. ...
For the objectives empirical therapy according to guidelines, de-escalation of therapy, switch from intravenous to oral treatment, therap
Topical antiviral and antifungal medications in pregnancy: a review of safety profiles
Patel VM, et al. J Eur Acad Dermatol Venereol 2017 - Review. PMID 28449377
For antiviral medications, acyclovir and trichloroacetic acid are safe to use in pregnancy. Docosanol, imiquimod and penciclovir are likely safe, but should be utilized as second-line agents. ...For antifungal medications, clotrimazole, miconazole and nystatin are considered first-line agents. Butenafine, ciclopirox, naftifine, oxiconazole and terbinafine may be utilized after the above agents. ...
For antiviral medications, acyclovir and trichloroacetic acid are safe to use in pregnancy. Docosanol, imiquimod and penciclovir are …
Antibiotics/antimicrobials: systemic and local administration in the therapy of mild to moderately advanced periodontitis
Jepsen K and Jepsen S. Periodontol 2000 2016 - Review. PMID 27045432
This review gives an update of the current scientific evidence on the efficacy of the adjunctive use of systemic and local antibiotics/antimicrobials in the treatment of periodontitis. In particular, it addresses whether their use can improve the results of nonsurgical mechanical therapy in mild-to-moderate forms of the disease. ...
This review gives an update of the current scientific evidence on the efficacy of the adjunctive use of systemic and local antibiotic …
Application of antimicrobial drugs in perioperative surgical incision
Yang X, et al. Ann Clin Microbiol Antimicrob 2018 - Review. PMID 29397046 Free PMC article.
Infection in surgical incision often results in poor wound healing, and one of the main factors for wound infection is the use of antimicrobial agents. ...Therefore, this review focuses on the use of different types of antimicrobial agents in surgical wounds....
Infection in surgical incision often results in poor wound healing, and one of the main factors for wound infection is the use of ant …
Inhaled anti-infective chemotherapy for respiratory tract infections: successes, challenges and the road ahead.
Velkov T, et al. Adv Drug Deliv Rev 2015 - Review. PMID 25446140 Free PMC article.
Inhaled anti-infective drugs are crucial for the prophylaxis and treatment of respiratory tract infections. The benefit of anti-infective drug delivery via inhalation is that it affords delivery of sufficient therapeutic dosages directly to the primary site of infection, while minimizing the risks of systemic toxicity or avoiding potential suboptimal pharmacokinetics/pharmacodynamics associated with systemic drug exposure. This review provides an up-to-date treatise of approved and novel developmental inhaled anti-infective agents, with particular attention to effective strategies for their use, pulmonary pharmacokinetic properties and safety....
Inhaled anti-infective drugs are crucial for the prophylaxis and treatment of respiratory tract infections. The benefit of …
387,309 results
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