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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1974 1
1975 2
1976 9
1977 10
1978 7
1979 13
1980 9
1981 10
1982 17
1983 24
1984 18
1985 8
1986 64
1987 134
1988 145
1989 154
1990 159
1991 171
1992 186
1993 187
1994 175
1995 260
1996 304
1997 299
1998 330
1999 356
2000 382
2001 474
2002 503
2003 471
2004 508
2005 626
2006 557
2007 488
2008 395
2009 433
2010 394
2011 417
2012 395
2013 470
2014 426
2015 381
2016 348
2017 275
2018 246
2019 132
2020 5
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10,772 results
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Page 1
Non-steroidal anti-inflammatory drug-induced cardiovascular adverse events: a meta-analysis.
Gunter BR, et al. J Clin Pharm Ther 2017 - Review. PMID 28019014
WHAT IS KNOWN AND OBJECTIVE: Although non-steroidal anti-inflammatory drugs (NSAIDs) have been studied in randomized, controlled trials and meta-analyses in an effort to determine their cardiovascular (CV) risks, no consensus has been reached. ...Comparisons were made between all included drugs, against placebo, and against non-selective NSAIDs (nsNSAIDs). Drugs were also compared against COX-2 selective inhibitors (COXIBs) with and without inclusion of rofecoxib. ...
WHAT IS KNOWN AND OBJECTIVE: Although non-steroidal anti-inflammatory drugs (NSAIDs) have been studied in random …
[Cardiovascular risk of non-steroidal anti-inflammatory drugs].
Prozzi GR, et al. Medicina (B Aires) 2018 - Review. PMID 30285927 Spanish. Free article.
Non-steroidal anti-inflammatories (NSAIDs) are among the most commonly used drugs in clinical practice. They block cyclooxygenases (COX) enzymes, but the degree of inhibition of COX-1 and COX-2 varies between them. In general, NSAIDs are classified in selective COX-2 or coxibs and non-selective or traditional NSAIDs. Both the analgesic and antiinflammatory effects, as well as the cardiovascular adverse effects, depend on the COX-2 inhibition. ...
Non-steroidal anti-inflammatories (NSAIDs) are among the most commonly used drugs in clinical practice. They blo
Cardiovascular safety of non-steroidal anti-inflammatory drugs: network meta-analysis.
Trelle S, et al. BMJ 2011 - Review. PMID 21224324 Free PMC article.
STUDY SELECTION: All large scale randomised controlled trials comparing any non-steroidal anti-inflammatory drug with other non-steroidal anti-inflammatory drugs or placebo. ...Cardiovascular risk needs to be taken into account when prescribing any non-steroidal anti-inflammatory drug....
STUDY SELECTION: All large scale randomised controlled trials comparing any non-steroidal anti-inflammatory drug …
Systematic review of nonsteroidal anti-inflammatory drug-induced adverse effects in dogs.
Monteiro-Steagall BP, et al. J Vet Intern Med 2013 - Review. PMID 23782347 Free article.
The aim of this systematic review was to identify, assess, and critically evaluate the quality of evidence of nonsteroidal anti-inflammatory drug (NSAID)-induced adverse effects in dogs. ...Adverse effects were detected in 35 studies (55%) and commonly included vomiting, diarrhea, and anorexia. Three studies (5%) reported a power analysis related to adverse effects of ≥80%. ...
The aim of this systematic review was to identify, assess, and critically evaluate the quality of evidence of nonsteroidal anti-in
Cardiovascular risk of non-steroidal anti-inflammatory drugs.
Alušík Š and Paluch Z. Vnitr Lek 2018. PMID 29766729
Non-steroidal anti-inflammatory drugs (NSAIDs) belong to the most widely used drugs. Results of recent large meta-analyses have shown that the cardiovascular risk of NSAIDs is more serious than originally believed and is not associated exclusively with coxibs; it is also increased when using so called traditional NSAIDs. ...The authors examine some results of meta-analyses and conclusions of regulatory agencies.Key words: cardiovascular risk - coxibs - diclofenac - ibuprofen - naproxen - non-steroidal anti-inflammatory drugs....
Non-steroidal anti-inflammatory drugs (NSAIDs) belong to the most widely used drugs. Results of recent large met
Adverse effects of nonsteroidal antiinflammatory drugs: an update of gastrointestinal, cardiovascular and renal complications.
Harirforoosh S, et al. J Pharm Pharm Sci 2013 - Review. PMID 24393558 Free article.
Non-steroidal anti-inflammatory drugs (NSAIDs) are used chronically to reduce pain and inflammation in patients with arthritic conditions, and also acutely as analgesics by many patients. Both therapeutic and adverse effects of NSAIDs are due to inhibition of cyclooxygenase (COX) enzyme. NSAIDs are classified as non-selective and COX-2-selective inhibitors (COXIBS) based on their extent of selectivity for COX inhibition. ...
Non-steroidal anti-inflammatory drugs (NSAIDs) are used chronically to reduce pain and inflammation in patients
Cardiovascular safety of non-steroidal anti-inflammatory drugs in chronic inflammatory rheumatic diseases.
Zavodovsky BV and Sivordova LE. Ter Arkh 2018 - Review. PMID 30701944
The main causes of increased cardiovascular risk are inflammatory heart and vascular lesions, accelerated progression of atherosclerosis and side effects of drug therapy. Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used in clinical practice and are on the list of the most prescribed medications. ...
The main causes of increased cardiovascular risk are inflammatory heart and vascular lesions, accelerated progression of atherosclero …
[Cardiovascular safety of non-steroidal anti-inflammatory drugs].
Møllersen MV, et al. Tidsskr Nor Laegeforen 2015 - Review. PMID 25806762 Norwegian. Free article.
We have evaluated data on adverse cardiovascular effects caused by COX-2 inhibitors and other non-steroidal anti-inflammatory drugs (NSAIDs) since 2004. ...The effects of length of treatment and predisposition for cardiovascular disease are less clear. INTERPRETATION: Adverse cardiovascular effects is as a group effect that applies to all the NSAIDs studied, except for naproxen and low-dose ibuprofen. ...
We have evaluated data on adverse cardiovascular effects caused by COX-2 inhibitors and other non-steroidal a
[Cardiovascular risks of non-steroidal anti-inflammatory drugs treatment].
Schmidt M, et al. Ugeskr Laeger 2016 - Review. PMID 28041549 Danish.
Non-aspirin non-steroidal anti-inflammatory drugs (NSAIDs) are among the most widely used drugs. Current evidence supports that all NSAIDs increase the risk of heart failure and elevate blood pressure, whereas the risk of thrombotic events varies with the type of drug. ...
Non-aspirin non-steroidal anti-inflammatory drugs (NSAIDs) are among the most widely used drugs. Current
Cyclo-Oxygenase (COX) Inhibitors and Cardiovascular Risk: Are Non-Steroidal Anti-Inflammatory Drugs Really Anti-Inflammatory?
Khan S, et al. Int J Mol Sci 2019 - Review. PMID 31480335 Free PMC article.
Cyclo-oxygenase (COX) inhibitors are among the most commonly used drugs in the western world for their anti-inflammatory and analgesic effects. ...
Cyclo-oxygenase (COX) inhibitors are among the most commonly used drugs in the western world for their anti-inflammatory and a …
10,772 results
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