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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1959 1
1962 1
1963 1
1964 5
1965 121
1966 108
1967 119
1968 112
1969 117
1970 107
1971 146
1972 140
1973 129
1974 111
1975 84
1976 105
1977 77
1978 115
1979 129
1980 89
1981 149
1982 148
1983 186
1984 175
1985 147
1986 181
1987 177
1988 209
1989 220
1990 218
1991 244
1992 239
1993 212
1994 294
1995 447
1996 577
1997 646
1998 651
1999 722
2000 770
2001 708
2002 804
2003 899
2004 869
2005 942
2006 1004
2007 1051
2008 1117
2009 1143
2010 1101
2011 1156
2012 1242
2013 1307
2014 1256
2015 1226
2016 1114
2017 998
2018 922
2019 412
2020 6
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25,648 results
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Page 1
Management of Depression in Older Adults: A Review
Kok RM and Reynolds CF. JAMA 2017 - Review. PMID 28535241
Antidepressants are the best-studied treatment option, but psychotherapy, exercise therapy, and electroconvulsive therapy may also be effective. ...Antidepressants can be gradually tapered over a period of several weeks, but discontinuation of antidepressants may be associated with relapse or recurrence of depression, so the patient should be closely observed. ...
Antidepressants are the best-studied treatment option, but psychotherapy, exercise therapy, and electroconvulsive therapy may also be
PSYCHOTHERAPY VERSUS PHARMACOTHERAPY FOR POSTTRAUMATIC STRESS DISORDER: SYSTEMIC REVIEW AND META-ANALYSES TO DETERMINE FIRST-LINE TREATMENTS
Lee DJ, et al. Depress Anxiety 2016 - Review. PMID 27126398
Aripiprazole, divalproex, guanfacine, and olanzapine failed to differentiate from placebo when combined with an antidepressant. ...
Aripiprazole, divalproex, guanfacine, and olanzapine failed to differentiate from placebo when combined with an antidepressant. ...
Antidepressants for irritable bowel syndrome-A systematic review.
Kułak-Bejda A, et al. Pharmacol Rep 2017 - Review. PMID 29132094
It is possible that antidepressant therapy may be more effective for patients with IBS. The aim of this study was a systematic review of the best available antidepressant therapies for IBS. ...Antidepressants might be an alternative therapy for patients suffering from IBS, especially diarrhea-predominant IBS....
It is possible that antidepressant therapy may be more effective for patients with IBS. The aim of this study was a systematic review …
Editorial
Dudek D, et al. Psychiatr Pol 2017. PMID 28866710 Free article.
Pharmacological approaches to the challenge of treatment-resistant depression
Ionescu DF, et al. Dialogues Clin Neurosci 2015 - Review. PMID 26246787 Free PMC article.
Although monoaminergic antidepressants revolutionized the treatment of Major Depressive Disorder (MDD) over a half-century ago, approximately one third of depressed patients experience treatment-resistant depression (TRD). ...Finally, we briefly review emerging targets for antidepressant drug discovery and the novel effects of rapidly acting antidepressants, with a focus on ketamine....
Although monoaminergic antidepressants revolutionized the treatment of Major Depressive Disorder (MDD) over a half-century ago, appro …
Effectiveness of Supplementary Cognitive-Behavioral Therapy for Pharmacotherapy-Resistant Depression: A Randomized Controlled Trial
Nakagawa A, et al. J Clin Psychiatry 2017 - Clinical Trial. PMID 28252882 Free article.
OBJECTIVE: Antidepressant medication is efficacious in the treatment of depression, but not all patients improve with antidepressant medication alone. ...Outpatients aged 20-65 years with pharmacotherapy-resistant depression (taking antidepressant medications for ≥ 8 weeks, 17-item GRID-Hamilton Depression Rating Scale [GRID-HDRS₁₇] score ≥ 16, Maudsley Staging Method for treatment-resistant depression score ≥ 3, and DSM-IV criteria for major depressive disorder) were randomly assigned (1:1) to CBT combined with TAU or to TAU alone. ...
OBJECTIVE: Antidepressant medication is efficacious in the treatment of depression, but not all patients improve with antidepressa
The overprescription of antidepressants and its impact on the elderly in Australia.
Alduhishy M. Trends Psychiatry Psychother 2018 - Review. PMID 30156645 Free article.
The scope intended here is specific to antidepressant use, or rather overuse, in Australia, but it can be compared to the use of other psychotropic drugs in most western countries. ...RESULTS: The past few decades have witnessed a surge in the use of psychotropic drugs, most notably antidepressants, in Australia and worldwide. ...
The scope intended here is specific to antidepressant use, or rather overuse, in Australia, but it can be compared to the use of othe …
Guidance for the discontinuation or switching of antidepressant therapies in adults.
Ogle NR and Akkerman SR. J Pharm Pract 2013 - Review. PMID 23459282
Antidepressants (ADs) are commonly used for the treatment of various psychological and other medical disorders. Patient response and regimen duration with individual agents varies, necessitating discontinuation (DC) and/or switching between ADs. ...
Antidepressants (ADs) are commonly used for the treatment of various psychological and other medical disorders. Patient response and
The Use of Antidepressants for Physical and Psychological Symptoms in Cancer.
Zaini S, et al. Curr Drug Targets 2018 - Review. PMID 29484993
Antidepressants are generally accepted for the treatment of depression among patients with or without cancer. Some other potential benefits of the antidepressants have been reported in cancer patients. ...CONCLUSION: More research studies with adequate statistical power are warranted to validate the use of antidepressants among cancer patients in treating these physical and psychological symptoms....
Antidepressants are generally accepted for the treatment of depression among patients with or without cancer. Some other potential be
Anxiety About Antidepressants.
Perlis RH. Am J Psychiatry 2018. PMID 29690791
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