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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1966 1
1967 13
1968 4
1969 8
1970 26
1971 48
1972 42
1973 24
1974 19
1975 18
1976 19
1977 30
1978 125
1979 290
1980 479
1981 518
1982 592
1983 715
1984 751
1985 909
1986 1003
1987 1047
1988 1018
1989 1292
1990 1588
1991 1759
1992 1940
1993 2006
1994 2016
1995 2051
1996 1925
1997 1907
1998 1894
1999 1817
2000 1742
2001 1793
2002 1736
2003 1703
2004 1808
2005 1895
2006 1993
2007 2059
2008 1915
2009 2071
2010 2156
2011 2171
2012 2153
2013 2203
2014 2048
2015 1999
2016 1746
2017 1676
2018 1500
2019 639
2020 8
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61,628 results
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Page 1
Is It Possible to Develop Cancer Vaccines to Neoantigens, What Are the Major Challenges, and How Can These Be Overcome? Neoantigens: Nothing New in Spite of the Name
Finn OJ and Rammensee HG. Cold Spring Harb Perspect Biol 2018 - Review. PMID 29254980 Free PMC article.
Contemporaneously, the budding field of immunology was posing the question can the immune system of animals or humans recognize a tumor that develops from one's own tissues and what types of antigens would distinguish the tumor from normal cells. Molecules encoded by oncogenic viruses provided the most logical candidates and evidence was quickly gathered for both humoral and cellular recognition of viral antigens, referred to as neoantigens. ...
Contemporaneously, the budding field of immunology was posing the question can the immune system of animals or humans recognize a tumor that …
The biology of influenza viruses
Bouvier NM and Palese P. Vaccine 2008 - Review. PMID 19230160 Free PMC article.
The influenza viruses are characterized by segmented, negative-strand RNA genomes requiring an RNA-dependent RNA polymerase of viral origin for replication. The particular structure ofthe influenza virus genome and function of its viral proteins enable antigenic drift and antigenic shift. ...
The influenza viruses are characterized by segmented, negative-strand RNA genomes requiring an RNA-dependent RNA polymerase of viral
The elucidation of non-classical MHC class II antigen processing through the study of viral antigens.
Veerappan Ganesan AP and Eisenlohr LC. Curr Opin Virol 2017 - Review. PMID 28081485 Free PMC article.
By convention, CD4(+) T cells are activated predominantly by Major Histocompatibility Complex class II-bound peptides derived from extracellular (exogenous) antigens. ...This review focuses on the contributions that studies of viral antigen have made to this shift in perspective, concluding with discussions of relevance to rational vaccine design, autoimmunity and cancer immunotherapy....
By convention, CD4(+) T cells are activated predominantly by Major Histocompatibility Complex class II-bound peptides derived from extracell …
Kinetic Changes of Viremia and Viral Antigens of Hepatitis B Virus During and After Pregnancy.
Liu J, et al. Medicine (Baltimore) 2015 - Clinical Trial. PMID 26559291 Free PMC article.
The authors aimed to clarify this issue by observing the kinetics of HBV deoxyribonucleic acid (DNA) and viral antigens in women during and after pregnancy. ...In addition, levels of HBV DNA and viral antigens in second trimester, around delivery, 6 to 8 weeks and 7 to 12 months postpartum showed no marked fluctuations, respectively. ...
The authors aimed to clarify this issue by observing the kinetics of HBV deoxyribonucleic acid (DNA) and viral antigens in wom …
Inactivation of viral antigens for vaccine preparation with particular reference to the application of binary ethylenimine.
Bahnemann HG. Vaccine 1990 - Review. PMID 2204242
Viral antigens for human and veterinary vaccines are still inactivated with formaldehyde. This is not an ideal inactivant and the problems of formaldehyde inactivation of vaccines are discussed. ...A computer program has been written for assistance in the use of BEI for controlled inactivation of viral antigens....
Viral antigens for human and veterinary vaccines are still inactivated with formaldehyde. This is not an ideal inactivant and
Large T and small T antigens of Merkel cell polyomavirus.
Wendzicki JA, et al. Curr Opin Virol 2015 - Review. PMID 25681708 Free PMC article.
A natural component of skin flora, MCV becomes tumorigenic only after integration into the host DNA together with specific mutations to the viral genome. Research on MCV large T (LT) and small T (sT) antigens, the only viral products expressed in MCC, shows that these major oncoproteins not only possess biochemical functions found in common with other polyomavirus T antigens, but also demonstrate new cellular targets not described in previous polyomavirus models. ...
A natural component of skin flora, MCV becomes tumorigenic only after integration into the host DNA together with specific mutations to the …
T cell recognition of hepatitis B and C viral antigens.
Jung MC, et al. Eur J Clin Invest 1994 - Review. PMID 7531642
Biological features of certain viral antigens have been partly characterized in animal models, but with the availability of modern molecular technology it is possible to extend these findings to the human system. ...By the use of synthetic peptides and vaccinia expression vectors, several epitopes for cytotoxic and helper T lymphocytes have been identified in HBV and HCV antigens. ...
Biological features of certain viral antigens have been partly characterized in animal models, but with the availability of mo …
Microtiter-Format Assays for HBV Antigen Quantitation in Nonclinical Applications
Goddard CD, et al. Methods Mol Biol 2017. PMID 27975318
Measurement of secreted HBV antigens in cell culture is an important endpoint in many experimental settings. Here we describe convenient and inexpensive protocols for 96-well format sandwich ELISA assays for this purpose, in which there are many options for customization of antibodies used and other parameters. ...
Measurement of secreted HBV antigens in cell culture is an important endpoint in many experimental settings. Here we describe conveni …
61,628 results
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