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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1962 1
1963 1
1964 2
1965 57
1966 115
1967 73
1968 123
1969 103
1970 99
1971 109
1972 100
1973 91
1974 96
1975 113
1976 104
1977 98
1978 99
1979 133
1980 143
1981 191
1982 178
1983 205
1984 240
1985 253
1986 238
1987 321
1988 339
1989 365
1990 317
1991 388
1992 351
1993 284
1994 290
1995 493
1996 566
1997 638
1998 697
1999 749
2000 848
2001 848
2002 938
2003 1077
2004 1091
2005 1012
2006 1061
2007 969
2008 1137
2009 1244
2010 1256
2011 1218
2012 1357
2013 1366
2014 1426
2015 1332
2016 1201
2017 1084
2018 1028
2019 423
2020 3
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29,006 results
Results by year
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Page 1
Antihypertensive drugs.
Laurent S. Pharmacol Res 2017 - Review. PMID 28780421
Successful treatment of hypertension is possible with limited side effects given the availability of multiple antihypertensive drug classes. ...Four additional pharmacological classes are described in a shorter manner: renin inhibitors, alpha-adrenergic receptor blockers, centrally acting agents, and direct acting vasodilators....
Successful treatment of hypertension is possible with limited side effects given the availability of multiple antihypertensive drug c …
First-line drugs for hypertension
Wright JM, et al. Cochrane Database Syst Rev 2018 - Review. PMID 29667175 Free PMC article.
Sustained moderate to severe elevations in resting blood pressure leads to a critically important clinical question: What class of drug to use first-line? ...OBJECTIVES: To quantify the mortality and morbidity effects from different first-line antihypertensive drug classes: thiazides (low-dose and high-dose), beta-blockers, calcium channel blockers, ACE inhibitors, angiotensin II receptor blockers (ARB), and alpha-blockers, compared to placebo or no treatment.Secondary objectives: when different antihypertensive drug classes are used as the first-line drug, to quantify the blood pressure lowering effect and the rate of withdrawal due to adverse drug effects, compared to placebo or no treatment. ...
Sustained moderate to severe elevations in resting blood pressure leads to a critically important clinical question: What class of drug to …
Pulmonary Arterial Hypertension
Dodson MW, et al. Heart Fail Clin 2018 - Review. PMID 29966625
Arterial hypertension
Kallikazaros IE. Hellenic J Cardiol 2013. PMID 24100188 Free article.
Effects of blood pressure lowering on outcome incidence in hypertension: 4. Effects of various classes of antihypertensive drugs--overview and meta-analyses.
Thomopoulos C, et al. J Hypertens 2015 - Review. PMID 25485720
In RCTs comparing calcium antagonists, angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) with placebo smaller SBP/DBP differences were achieved, mostly because in the majority of these later RCTs the antihypertensive drug and placebo were added on a background treatment with other antihypertensive agents. ...CONCLUSION: BP lowering by all classes of antihypertensive drugs is accompanied by significant reductions of stroke and major cardiovascular events. ...
In RCTs comparing calcium antagonists, angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) with placebo …
Pharmacotherapy for hypertension in adults aged 18 to 59 years
Musini VM, et al. Cochrane Database Syst Rev 2017 - Review. PMID 28813123 Free PMC article.
Systematic reviews have shown proven benefit of antihypertensive drug therapy in reducing cardiovascular morbidity and mortality but most of the evidence is in people 60 years of age and older. ...OBJECTIVES: To quantify antihypertensive drug effects on all-cause mortality in adults aged 18 to 59 years with mild to moderate primary hypertension. ...
Systematic reviews have shown proven benefit of antihypertensive drug therapy in reducing cardiovascular morbidity and mortality but …
Factors associated with the use of antihypertensives among seniors.
Massa KH, et al. Rev Saude Publica 2016. PMID 28099659 Free PMC article.
OBJECTIVE: Analyze the use of antihypertensives among seniors and the association with socioeconomic and behavioral characteristics. ...RESULTS: We observed increased proportion of use of antihypertensive, from 48.7% in 2000 to 61.3% in 2006, reaching 65.7% in 2010. ...
OBJECTIVE: Analyze the use of antihypertensives among seniors and the association with socioeconomic and behavioral characteri …
[Clinical cases]
Nafría AG, et al. Hipertens Riesgo Vasc 2017. PMID 29908666 Spanish.
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