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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1925 1
1947 2
1952 3
1955 2
1956 1
1958 1
1959 1
1960 3
1961 2
1963 1
1964 3
1965 3
1966 1
1967 3
1968 3
1969 7
1970 6
1971 9
1972 5
1973 16
1974 11
1975 47
1976 43
1977 39
1978 58
1979 59
1980 53
1981 81
1982 81
1983 101
1984 116
1985 158
1986 142
1987 166
1988 167
1989 205
1990 231
1991 248
1992 281
1993 273
1994 250
1995 307
1996 325
1997 290
1998 321
1999 262
2000 327
2001 380
2002 382
2003 398
2004 490
2005 500
2006 536
2007 594
2008 645
2009 663
2010 733
2011 756
2012 858
2013 910
2014 928
2015 988
2016 1050
2017 1108
2018 1095
2019 1179
2020 1289
2021 1308
2022 1349
2023 1250
2024 1173
2025 20

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22,946 results

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Page 1
Hormesis defines the limits of lifespan.
Calabrese EJ, Osakabe N, Di Paola R, Siracusa R, Fusco R, D'Amico R, Impellizzeri D, Cuzzocrea S, Fritsch T, Abdelhameed AS, Wenzel U, Franceschi C, Calabrese V. Calabrese EJ, et al. Ageing Res Rev. 2023 Nov;91:102074. doi: 10.1016/j.arr.2023.102074. Epub 2023 Sep 13. Ageing Res Rev. 2023. PMID: 37709054 Free article. Review.
It proposes that the most fundamental, evolutionary-based integrative strategy to sustain and protect health is based on the concept of hormesis. This concept integrates anti-oxidant, anti-inflammatory and cellular repair responses at all levels of biological organization …
It proposes that the most fundamental, evolutionary-based integrative strategy to sustain and protect health is based on the concept of h …
The hormesis principle of neuroplasticity and neuroprotection.
Mattson MP, Leak RK. Mattson MP, et al. Cell Metab. 2024 Feb 6;36(2):315-337. doi: 10.1016/j.cmet.2023.12.022. Epub 2024 Jan 10. Cell Metab. 2024. PMID: 38211591 Review.
These phylogenetically conserved processes are the foundation of the hormesis principle, in which single or repeated exposures to low levels of environmental challenges improve cellular and organismal fitness and raise the probability of survival. ...Here we review the phy …
These phylogenetically conserved processes are the foundation of the hormesis principle, in which single or repeated exposures to low …
Hormesis determines lifespan.
Calabrese EJ, Nascarella M, Pressman P, Hayes AW, Dhawan G, Kapoor R, Calabrese V, Agathokleous E. Calabrese EJ, et al. Ageing Res Rev. 2024 Feb;94:102181. doi: 10.1016/j.arr.2023.102181. Epub 2024 Jan 3. Ageing Res Rev. 2024. PMID: 38182079 Review.
This evaluation was framed within the context of hormesis, a biphasic dose response with specific quantitative features describing the limits of biological/phenotypic plasticity for integrative biological endpoints (e.g., cell proliferation, memory, fecundity, growth, tiss …
This evaluation was framed within the context of hormesis, a biphasic dose response with specific quantitative features describing th …
Hormesis Promotes Evolutionary Change.
Costantini D. Costantini D. Dose Response. 2019 Apr 24;17(2):1559325819843376. doi: 10.1177/1559325819843376. eCollection 2019 Apr-Jun. Dose Response. 2019. PMID: 31040761 Free PMC article. Review.
This evidence would support the hypothesis that hormesis is an evolutionary expectation. In this short review, I discuss relevant examples of genetic and phenotypic responses to moderate stress exposure that are compatible with hormesis and with paradigms of evoluti …
This evidence would support the hypothesis that hormesis is an evolutionary expectation. In this short review, I discuss relevant exa …
Nutritional hormesis.
Hayes DP. Hayes DP. Eur J Clin Nutr. 2007 Feb;61(2):147-59. doi: 10.1038/sj.ejcn.1602507. Epub 2006 Aug 2. Eur J Clin Nutr. 2007. PMID: 16885926 Review.
OBJECTIVE: Hormesis, the biological and toxicological concept that small quantities have opposite effects from large quantities, is reviewed with emphasis on its relevance to nutrition. ...CONCLUSIONS: The credence and relevance of hormesis to nutrition are consider …
OBJECTIVE: Hormesis, the biological and toxicological concept that small quantities have opposite effects from large quantities, is r …
Hormesis: Highly Generalizable and Beyond Laboratory.
Agathokleous E, Kitao M, Calabrese EJ. Agathokleous E, et al. Trends Plant Sci. 2020 Nov;25(11):1076-1086. doi: 10.1016/j.tplants.2020.05.006. Epub 2020 Jun 13. Trends Plant Sci. 2020. PMID: 32546350 Review.
Hormesis is a biphasic dose-response relationship with contrasting effects of low versus high doses of stress. ...Here, we explore selected areas of importance to the concept of hormesis and suggest that hormesis is a highly generalizable phenomenon. We addre …
Hormesis is a biphasic dose-response relationship with contrasting effects of low versus high doses of stress. ...Here, we explore se …
Hormesis with pesticides.
Duke SO. Duke SO. Pest Manag Sci. 2014 May;70(5):689. doi: 10.1002/ps.3756. Pest Manag Sci. 2014. PMID: 24729579 No abstract available.
Radiation hormesis.
Macklis RM, Beresford B. Macklis RM, et al. J Nucl Med. 1991 Feb;32(2):350-9. J Nucl Med. 1991. PMID: 1992042 Free article. Review.
"Radiation hormesis" is the name given to the putative stimulatory effects of low level ionizing radiation (generally in the range of 1-50 cGy of low-LET radiation). ...This review summarizes some of the relevant historical and scientific data bearing on the question of ra …
"Radiation hormesis" is the name given to the putative stimulatory effects of low level ionizing radiation (generally in the range of …
Building Biological Shields via Hormesis.
Calabrese EJ, Agathokleous E. Calabrese EJ, et al. Trends Pharmacol Sci. 2019 Jan;40(1):8-10. doi: 10.1016/j.tips.2018.10.010. Epub 2018 Nov 16. Trends Pharmacol Sci. 2019. PMID: 30455065 Review.
Hormesis offers the potential to build biological shields to protect against a plethora of age-related diseases and acute trauma (e.g., brain traumatic injury) via the implementation of pre- and postconditioning strategies. ...
Hormesis offers the potential to build biological shields to protect against a plethora of age-related diseases and acute trauma (e.g …
Defining hormesis.
Calabrese EJ, Baldwin LA. Calabrese EJ, et al. Hum Exp Toxicol. 2002 Feb;21(2):91-7. doi: 10.1191/0960327102ht217oa. Hum Exp Toxicol. 2002. PMID: 12102503
Much confusion surrounds the concept of hormesis and what its biological meaning represents. This paper provides a definition of hormesis that addresses its historical foundations, quantitative features, and underlying evolutionary and toxicologically based mechanis …
Much confusion surrounds the concept of hormesis and what its biological meaning represents. This paper provides a definition of h …
22,946 results
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