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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 2
1966 2
1967 3
1968 3
1969 2
1970 1
1972 1
1973 3
1974 3
1975 1
1976 2
1977 1
1978 1
1979 1
1980 6
1981 2
1982 13
1983 7
1984 15
1985 9
1986 6
1987 18
1988 25
1989 13
1990 16
1991 15
1992 20
1993 18
1994 37
1995 69
1996 115
1997 184
1998 264
1999 334
2000 377
2001 375
2002 370
2003 362
2004 376
2005 408
2006 412
2007 519
2008 484
2009 462
2010 496
2011 467
2012 465
2013 456
2014 447
2015 395
2016 415
2017 369
2018 311
2019 144
2020 1
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8,746 results
Results by year
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Page 1
Adverse effects and drug interactions of clinical importance with antiviral drugs.
Morris DJ. Drug Saf 1994 - Review. PMID 8018300
Idoxuridine must be administered topically, given the severity of its systemic adverse effects. Drug interactions involving antiviral agents mostly reflect shared toxicity with other agents (e.g. neutropenia with ganciclovir and zidovudine, pancreatitis with didanosine and alcohol), although renal excretion or hepatic metabolism may be implicated. Given the possibility of severe adverse reactions and drug interactions, antiviral chemotherapy should only be used for potentially serious virus infections. ...
Idoxuridine must be administered topically, given the severity of its systemic adverse effects. Drug interactions involving …
A review of the toxicity of HIV medications
Margolis AM, et al. J Med Toxicol 2014 - Review. PMID 23963694 Free PMC article.
Clinicians should be able to recognize effects of chronic toxicity of ARVs, especially mitochondrial toxicity....
Clinicians should be able to recognize effects of chronic toxicity of ARVs, especially mitochondrial toxicity....
A Systems Approach to Study Immuno- and Neuro-Modulatory Properties of Antiviral Agents.
Zusinaite E, et al. Viruses 2018 - Review. PMID 30103549 Free PMC article.
There are dozens of approved, investigational and experimental antiviral agents. Many of these agents cause serious side effects, which can only be revealed after drug administration. Identification of the side effects prior to drug administration is challenging. Here we describe an ex vivo approach for studying immuno- and neuro-modulatory properties of antiviral agents, which may be associated with potential side effects of these therapeutics. ...
There are dozens of approved, investigational and experimental antiviral agents. Many of these agents cause serious sid …
Neurological and psychiatric adverse effects of antiretroviral drugs.
Abers MS, et al. CNS Drugs 2014 - Review. PMID 24362768
Antiretroviral drugs are associated with a variety of adverse effects on the central and peripheral nervous systems. The frequency and severity of neuropsychiatric adverse events is highly variable, with differences between the antiretroviral classes and amongst the individual drugs in each class. ...Recent studies have suggested that the risk of developing these adverse effects is increased in patients with various cytochrome P450 2B6 alleles. ...
Antiretroviral drugs are associated with a variety of adverse effects on the central and peripheral nervous systems. The frequ …
[Adverse effects of antiviral agents].
Moriuchi M and Moriuchi H. Nihon Rinsho 2007 - Review. PMID 18074544 Japanese.
Antiviral drug-induced nephrotoxicity.
Izzedine H, et al. Am J Kidney Dis 2005 - Review. PMID 15861345
The exact frequency of nephrotoxicity induced by antiviral drugs is difficult to determine. Antiviral drugs cause renal failure through a variety of mechanisms. ...Renal injury associated with antiviral drugs involves diverse processes having effects on the renal transporters, as well as on tubule cells. ...
The exact frequency of nephrotoxicity induced by antiviral drugs is difficult to determine. Antiviral drugs cause renal failur …
The tuberculosis-associated immune reconstitution inflammatory syndrome: recent advances in clinical and pathogenesis research
Walker NF, et al. Curr Opin HIV AIDS 2018. PMID 30124473 Free PMC article.
Prednisone initiated alongside ART in selected patients with CD4 less than 100 cells/μl reduced the risk of paradoxical TB-IRIS by 30% in a recent randomized-controlled trial (RCT) and was not associated with significant adverse effects. ...
Prednisone initiated alongside ART in selected patients with CD4 less than 100 cells/μl reduced the risk of paradoxical TB-IRIS by 30% in a …
[Adverse effects of antiretroviral agents, and their treatment].
Shirasaka T. Nihon Rinsho 2010 - Review. PMID 20229794 Japanese.
However, side effects have been reported with all antiretroviral agents and are the common reasons for switching or discontinuing therapy and for poor adherence. ...In this paper, the common adverse effects of major antiretroviral agents, potential preventive measures, and suggested management strategies are described....
However, side effects have been reported with all antiretroviral agents and are the common reasons for switching or discontinu …
Neuropsychiatric Effects of HIV Antiviral Medications.
Treisman GJ and Soudry O. Drug Saf 2016 - Review. PMID 27534750
The development of antiretroviral therapy (ART) has dramatically increased the lifespan of HIV patients but treatment is complicated by numerous adverse effects and toxicities. ...Even in careful studies, it may be difficult to determine which effects are related to the virus, the immune system, or the treatment. ...
The development of antiretroviral therapy (ART) has dramatically increased the lifespan of HIV patients but treatment is complicated by nume …
[Safety of the Russian antiviral drug Kagocel].
Borovskaya TG. Ter Arkh 2017 - Review. PMID 29260752 Russian.
The review gives summarized information on the preclinical data and clinical trials evaluating the safety of the antiviral drug Kagocel. ...The results given in the review lead to the conclusion that the use of the antiviral drug Kagocel in both general and pediatric practice is proven safe....
The review gives summarized information on the preclinical data and clinical trials evaluating the safety of the antiviral drug Kagoc …
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