Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

MyNCBI Filters
Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1991 1
1992 34
1993 150
1994 254
1995 447
1996 679
1997 842
1998 1010
1999 1226
2000 1578
2001 1496
2002 1574
2003 1876
2004 2216
2005 2457
2006 2681
2007 2848
2008 2945
2009 2845
2010 2984
2011 3261
2012 3413
2013 3507
2014 3566
2015 3496
2016 3652
2017 3329
2018 3292
2019 1640
2020 40
Text availability
Article attribute
Article type
Publication date

Search Results

52,944 results
Results by year
Filters applied: . Clear all
Page 1
Proliferation, cell cycle and apoptosis in cancer.
Evan GI and Vousden KH. Nature 2001 - Review. PMID 11357141
One of these is deregulated cell proliferation, which, together with the obligate compensatory suppression of apoptosis needed to support it, provides a minimal 'platform' necessary to support further neoplastic progression. ...
One of these is deregulated cell proliferation, which, together with the obligate compensatory suppression of apoptosis needed to sup …
Molecular Targeted Therapies Elicit Concurrent Apoptotic and GSDME-Dependent Pyroptotic Tumor Cell Death
Lu H, et al. Clin Cancer Res 2018. PMID 30061362 Free article.
Functional impact of pyroptosis on drug response was investigated in cell lines and xenograft models. RESULTS: We showed that diverse small-molecule inhibitors specifically targeting KRAS-, EGFR-, or ALK-driven lung cancer uniformly elicited robust pyroptotic cell death, in addition to simultaneously invoking cellular apoptosis. ...As a result, cooccurrence and interplay of apoptosis and pyroptosis were widespread in lung cancer cells, succumbing to genotype-matched regimens. ...
Functional impact of pyroptosis on drug response was investigated in cell lines and xenograft models. RESULTS: We showed that diverse …
Lipid metabolism, apoptosis and cancer therapy.
Huang C and Freter C. Int J Mol Sci 2015 - Review. PMID 25561239 Free PMC article.
Lipid metabolism participates in the regulation of many cellular processes such as cell growth, proliferation, differentiation, survival, apoptosis, inflammation, motility, membrane homeostasis, chemotherapy response, and drug resistance. Bioactive lipid molecules promote apoptosis via the intrinsic pathway by modulating mitochondrial membrane permeability and activating different enzymes including caspases. ...
Lipid metabolism participates in the regulation of many cellular processes such as cell growth, proliferation, differentiation, survival, …
Apoptosis and drug response.
Houghton JA. Curr Opin Oncol 1999 - Review. PMID 10550011
Recent investigation further defines the role of p53 and of signaling events upstream and downstream of p53 in apoptosis following drug-induced DNA damage. ...Apoptosis has been accepted as the predominant mechanism of drug-induced cell death in preclinical experimental models and in clinically sensitive tumors. ...
Recent investigation further defines the role of p53 and of signaling events upstream and downstream of p53 in apoptosis following …
Selective drug-free cancer apoptosis by three-dimensional self-targeting magnetic nickel oxide nanomatrix.
Vijayakumar SC, et al. Nanomedicine (Lond) 2018. PMID 30328379
The 3D nanomatrix structure altered HeLa cell behavior and induced apoptosis cancer apoptosis with an evidence of increased endocytosis when compared with fibroblast cells. CONCLUSION: The results demonstrate the availability of new potential avenues for magnetic drug-free cancer therapeutics....
The 3D nanomatrix structure altered HeLa cell behavior and induced apoptosis cancer apoptosis with an evidence of increased en …
Role of pyroptosis in cardiovascular disease
Zhaolin Z, et al. Cell Prolif 2019 - Review. PMID 30525268
This review summarizes the molecular mechanisms, regulation and cellular effects of pyroptosis briefly and then discusses the current pyroptosis studies in CVD research....
This review summarizes the molecular mechanisms, regulation and cellular effects of pyroptosis briefly and then discusses the current …
Anoikis and EMT: Lethal "Liaisons" during Cancer Progression
Cao Z, et al. Crit Rev Oncog 2016 - Review. PMID 27915969 Free PMC article.
The investigation of drug discovery platforms for apoptosis-driven therapeutics identified several novel agents with antitumor action via reversing resistance to anoikis, inhibiting survival pathways and impacting the EMT landscape in human cancer. In this review, we discuss current evidence on the contribution of the anoikis phenomenon functionally linked to EMT to cancer metastasis and the therapeutic value of antitumor drugs that selectively reverse anoikis resistance and/or EMT to impair tumor progression toward the development/optimization of apoptosis-driven therapeutic targeting of metastatic disease....
The investigation of drug discovery platforms for apoptosis-driven therapeutics identified several novel agents with antitumor …
Effects of maslinic acid on the proliferation and apoptosis of A549 lung cancer cells.
Bai X, et al. Mol Med Rep 2016. PMID 26572558 Free PMC article.
In addition, Annexin V/propidium iodide flow cytometric analysis demonstrated that MA induced apoptosis of A549 cells. The present study also confirmed that MA induced apoptosis by observing morphological alterations. ...The level of inhibitors of apoptosis (IAPs) and Smac, which are possible upstream factors of caspase proteins, were also examined. ...
In addition, Annexin V/propidium iodide flow cytometric analysis demonstrated that MA induced apoptosis of A549 cells. The present st …
52,944 results
Jump to page
Feedback