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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1992 7
1993 28
1994 61
1995 113
1996 155
1997 190
1998 215
1999 234
2000 246
2001 246
2002 211
2003 235
2004 228
2005 221
2006 218
2007 222
2008 188
2009 235
2010 163
2011 153
2012 156
2013 165
2014 163
2015 126
2016 87
2017 72
2018 92
2019 34
2020 1
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4,197 results
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Page 1
Apoptosis and Clearance of Apoptotic Cells.
Nagata S. Annu Rev Immunol 2018 - Review. PMID 29400998
Dead cells generated by apoptosis are quickly engulfed by macrophages for degradation. Caspases are a large family of cysteine proteases that act in cascades. A cascade that leads to caspase 3 activation mediates apoptosis and is responsible for killing cells, recruiting macrophages, and presenting an "eat me" signal(s). ...
Dead cells generated by apoptosis are quickly engulfed by macrophages for degradation. Caspases are a large family of cysteine protea …
Immunogenic cell death
Garg AD, et al. Int J Dev Biol 2015 - Review. PMID 26374534 Free article.
Role of apoptosis and autophagy in tuberculosis.
Lam A, et al. Am J Physiol Lung Cell Mol Physiol 2017 - Review. PMID 28495854 Free PMC article.
Apoptosis and autophagy of macrophages play a vital role in the pathogenesis and also in the host defense against Mtb. This review will outline the role of these two cellular processes in defense against Mtb with particular emphasis on innate immunity and explore developing therapies aimed at altering host responses to the disease....
Apoptosis and autophagy of macrophages play a vital role in the pathogenesis and also in the host defense against Mtb. This review wi
Apoptosis.
Fleisher TA. Ann Allergy Asthma Immunol 1997 - Review. PMID 9087147
LEARNING OBJECTIVES: Reading this article will introduce the reader to the basic concept of physiologic cell death referred to as apoptosis. In addition, the role of apoptosis in immune function as well as its contribution to various clinical disorders will be developed. ...
LEARNING OBJECTIVES: Reading this article will introduce the reader to the basic concept of physiologic cell death referred to as apoptos
Apoptosis and Necroptosis as Host Defense Strategies to Prevent Viral Infection.
Orzalli MH and Kagan JC. Trends Cell Biol 2017 - Review. PMID 28642032 Free PMC article.
In this review we discuss the mechanisms by which PRRs can serve dual roles as initiators of inflammatory gene expression and as inducers of apoptosis and necroptosis following virus infection....
In this review we discuss the mechanisms by which PRRs can serve dual roles as initiators of inflammatory gene expression and as inducers of …
Immunogenic Apoptotic Cell Death and Anticancer Immunity
Vandenabeele P, et al. Adv Exp Med Biol 2016 - Review. PMID 27558820
However, accumulating experimental data indicate that certain anticancer therapies can induce an immunogenic form of apoptosis associated with the emission of damage-associated molecular patterns (DAMPs), which function as adjuvants to activate host antitumor immune responses. ...In the final part, we discuss the role of radiotherapy-induced immunogenic apoptosis and the relationship of its immunogenicity to the fraction dose and concomitant chemotherapy....
However, accumulating experimental data indicate that certain anticancer therapies can induce an immunogenic form of apoptosis associ …
Where Have All the Flowers Gone?
Marrack P. J Immunol 2018. PMID 29914935 Free article.
Functional significance of the perforin/granzyme cell death pathway
Trapani JA and Smyth MJ. Nat Rev Immunol 2002 - Review. PMID 12360212
Perforin/granzyme-induced apoptosis is the main pathway used by cytotoxic lymphocytes to eliminate virus-infected or transformed cells. Studies in gene-disrupted mice indicate that perforin is vital for cytotoxic effector function; it has an indispensable, but undefined, role in granzyme-mediated apoptosis. ...
Perforin/granzyme-induced apoptosis is the main pathway used by cytotoxic lymphocytes to eliminate virus-infected or transformed cell …
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