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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1955 1
1991 1
1992 1
1993 1
1994 9
1995 18
1996 28
1997 59
1998 105
1999 155
2000 245
2001 398
2002 418
2003 568
2004 690
2005 819
2006 956
2007 1058
2008 1104
2009 1175
2010 1287
2011 1371
2012 1399
2013 1416
2014 1489
2015 1538
2016 1094
2017 939
2018 946
2019 402
2020 4
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17,445 results
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Page 1
Caspase-1 initiates apoptosis in the absence of gasdermin D.
Tsuchiya K, et al. Nat Commun 2019. PMID 31064994 Free PMC article.
Chemical dimerization of caspase-1 induces pyroptosis in GSDMD-sufficient cells, but apoptosis in GSDMD-deficient cells. Caspase-1-induced apoptosis involves the Bid-caspase-9-caspase-3 axis, which can be followed by GSDME-dependent secondary necrosis/pyroptosis. ...This study clarifies the molecular mechanism and biological roles of caspase-1-induced apoptosis in GSDMD-low/null cell types....
Chemical dimerization of caspase-1 induces pyroptosis in GSDMD-sufficient cells, but apoptosis in GSDMD-deficient cells. Caspase-1-in …
The Ambivalent Function of YAP in Apoptosis and Cancer.
Zhang X, et al. Int J Mol Sci 2018 - Review. PMID 30486435 Free PMC article.
Unfortunately, more and more evidence demonstrates that this protein is also an essential contributor of p73-mediated apoptosis. ...This review also summarized the molecules, processes and drugs, which regulate Hippo-YAP signaling and discusses their effect on apoptosis. ...
Unfortunately, more and more evidence demonstrates that this protein is also an essential contributor of p73-mediated apoptosis. ...T …
Fundamental Mechanisms of Regulated Cell Death and Implications for Heart Disease
Del Re DP, et al. Physiol Rev 2019 - Review. PMID 31364924 Free PMC article.
We review in detail the basic biology of nine including death receptor-mediated apoptosis, death receptor-mediated necrosis (necroptosis), mitochondrial-mediated apoptosis, mitochondrial-mediated necrosis, autophagy-dependent cell death, ferroptosis, pyroptosis, parthanatos, and immunogenic cell death. ...While a role for apoptosis in ischemia/reperfusion cannot be excluded, regulated forms of necrosis, through both death receptor and mitochondrial pathways, are critical. ...
We review in detail the basic biology of nine including death receptor-mediated apoptosis, death receptor-mediated necrosis (necropto …
Cell Death in the Kidney
Priante G, et al. Int J Mol Sci 2019 - Review. PMID 31340541 Free PMC article.
What distinguishes necrosis from apoptosis is the rupture of the plasma membrane, so necrotic cell death is accompanied by the release of unprocessed intracellular content, including cellular organelles, which are highly immunogenic proteins. The relative contribution of apoptosis and necrosis to injury varies, depending on the severity of the insult. Regulated cell death may result from immunologically silent apoptosis or from immunogenic necrosis. ...
What distinguishes necrosis from apoptosis is the rupture of the plasma membrane, so necrotic cell death is accompanied by the releas …
To the edge of cell death and back
Gong YN, et al. FEBS J 2019 - Review. PMID 30506628 Free PMC article.
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