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1,002 results

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Quoted phrase not found in phrase index: "Application site anaesthesia"
Page 1
Pharmacokinetic-pharmacodynamic model for propofol for broad application in anaesthesia and sedation.
Eleveld DJ, Colin P, Absalom AR, Struys MMRF. Eleveld DJ, et al. Br J Anaesth. 2018 May;120(5):942-959. doi: 10.1016/j.bja.2018.01.018. Epub 2018 Mar 12. Br J Anaesth. 2018. PMID: 29661412 Free article.
BACKGROUND: Pharmacokinetic (PK) and pharmacodynamic (PD) models are used in target-controlled-infusion (TCI) systems to determine the optimal drug administration to achieve a desired target concentration in a central or effect-site compartment. Our aim was to develop a PK …
BACKGROUND: Pharmacokinetic (PK) and pharmacodynamic (PD) models are used in target-controlled-infusion (TCI) systems to determine the optim …
Updates in our understanding of local anaesthetic systemic toxicity: a narrative review.
Macfarlane AJR, Gitman M, Bornstein KJ, El-Boghdadly K, Weinberg G. Macfarlane AJR, et al. Anaesthesia. 2021 Jan;76 Suppl 1:27-39. doi: 10.1111/anae.15282. Anaesthesia. 2021. PMID: 33426662 Free article. Review.
Despite advances in clinical practice, local anaesthetic systemic toxicity continues to occur with the therapeutic use of local anaesthesia. Patterns of presentation have evolved over recent years due in part to the increasing use of ultrasound which has been demonstrated …
Despite advances in clinical practice, local anaesthetic systemic toxicity continues to occur with the therapeutic use of local anaesthes …
Clinical Pharmacokinetics and Pharmacodynamics of Propofol.
Sahinovic MM, Struys MMRF, Absalom AR. Sahinovic MM, et al. Clin Pharmacokinet. 2018 Dec;57(12):1539-1558. doi: 10.1007/s40262-018-0672-3. Clin Pharmacokinet. 2018. PMID: 30019172 Free PMC article. Review.
Due to its narrow therapeutic margin, propofol should only be administered by practitioners trained and experienced in providing general anaesthesia. Many pharmacokinetic (PK) and pharmacodynamic (PD) models for propofol exist. ...In this review, we provide an overview of …
Due to its narrow therapeutic margin, propofol should only be administered by practitioners trained and experienced in providing general …
The Erector Spinae Plane Block: A Novel Analgesic Technique in Thoracic Neuropathic Pain.
Forero M, Adhikary SD, Lopez H, Tsui C, Chin KJ. Forero M, et al. Reg Anesth Pain Med. 2016 Sep-Oct;41(5):621-7. doi: 10.1097/AAP.0000000000000451. Reg Anesth Pain Med. 2016. PMID: 27501016
In this report, we describe a novel interfascial plane block, the erector spinae plane (ESP) block, and its successful application in 2 cases of severe neuropathic pain (the first resulting from metastatic disease of the ribs, and the second from malunion of multiple rib f …
In this report, we describe a novel interfascial plane block, the erector spinae plane (ESP) block, and its successful application in …
Intraoperative Nociception Monitoring.
Shanthanna H, Uppal V, Joshi GP. Shanthanna H, et al. Anesthesiol Clin. 2021 Sep;39(3):493-506. doi: 10.1016/j.anclin.2021.03.008. Epub 2021 Jul 12. Anesthesiol Clin. 2021. PMID: 34392881 Review.
Its monitoring can have potential benefits. Under anesthesia, nociceptive signals are continuously generated to cause involuntary effects on the autonomic nervous system, reflex movement, and stress response. ...Despite advances in monitoring technology and availability, t …
Its monitoring can have potential benefits. Under anesthesia, nociceptive signals are continuously generated to cause involuntary eff …
Local anesthetics.
Yanagidate F, Strichartz GR. Yanagidate F, et al. Handb Exp Pharmacol. 2007;(177):95-127. doi: 10.1007/978-3-540-33823-9_4. Handb Exp Pharmacol. 2007. PMID: 17087121 Review.
Such inhibition results from drug binding at a site in the channel's inner pore, accessible from the cytoplasmic opening. Binding of drug molecules to these channels depends on their conformation, with the drugs generally having a higher affinity for the open and inactivat …
Such inhibition results from drug binding at a site in the channel's inner pore, accessible from the cytoplasmic opening. Binding of …
[Mediastinoscopy].
Sarrazin R, Dyon JF. Sarrazin R, et al. Rev Mal Respir. 1992;9(1):99-110. Rev Mal Respir. 1992. PMID: 1542754 Review. French.
Mediastinoscopy is used to assess prognosis as regards the extension of broncho-pulmonary cancer. The existence and the site of metastatic nodes can be precisely assessed possibly on the contralateral side too, and influences the therapeutic orientation. ...Computered tomo …
Mediastinoscopy is used to assess prognosis as regards the extension of broncho-pulmonary cancer. The existence and the site of metas …
Surgery in fish.
Harms CA, Lewbart GA. Harms CA, et al. Vet Clin North Am Exot Anim Pract. 2000 Sep;3(3):759-74. doi: 10.1016/s1094-9194(17)30074-9. Vet Clin North Am Exot Anim Pract. 2000. PMID: 11228930 Review.
Surgery in fish is feasible and practical for clinical and research applications. Certain adjustments in standard surgical procedures are necessary to accommodate piscine tissue handling, skin sensitivity, aqueous respiration, anatomic variations, and patient size. General …
Surgery in fish is feasible and practical for clinical and research applications. Certain adjustments in standard surgical procedures …
Opioids and breathing.
Santiago TV, Edelman NH. Santiago TV, et al. J Appl Physiol (1985). 1985 Dec;59(6):1675-85. doi: 10.1152/jappl.1985.59.6.1675. J Appl Physiol (1985). 1985. PMID: 2934364 Review.
These developments include demonstration of receptors and site-specific effects of application of opioids in the pons and medulla, demonstration of variable tolerance of respiratory responses in addicted individuals as well as their offspring, and demonstration of a …
These developments include demonstration of receptors and site-specific effects of application of opioids in the pons and medu …
Best practices for blood collection and anaesthesia in mice: Selection, application and reporting.
Li Z, LoBue A, Heuser SK, Li J, Engelhardt E, Papapetropoulos A, Patel HH, Lilley E, Ferdinandy P, Schulz R, Cortese-Krott MM. Li Z, et al. Br J Pharmacol. 2025 Jun;182(11):2337-2353. doi: 10.1111/bph.70029. Epub 2025 Apr 15. Br J Pharmacol. 2025. PMID: 40234101 Review.
The choice of blood collection method and the need for analgesia and/or anaesthesia depend on multiple factors, including the experimental setup, animal welfare considerations and the intended downstream analyses. This minireview describes key non-surgical and surgical blo …
The choice of blood collection method and the need for analgesia and/or anaesthesia depend on multiple factors, including the experim …
1,002 results