Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

MyNCBI Filters
Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1975 1
1976 1
1977 3
1978 4
1979 8
1980 7
1981 14
1982 27
1983 12
1984 13
1985 26
1986 41
1987 61
1988 40
1989 45
1990 75
1991 59
1992 58
1993 80
1994 78
1995 61
1996 92
1997 86
1998 80
1999 100
2000 106
2001 149
2002 156
2003 191
2004 226
2005 311
2006 339
2007 374
2008 403
2009 331
2010 301
2011 367
2012 335
2013 340
2014 308
2015 331
2016 320
2017 357
2018 273
2019 151
2020 6
Text availability
Article attribute
Article type
Publication date

Search Results

6,098 results
Results by year
Filters applied: . Clear all
Page 1
Aromatase inhibitors (letrozole) for subfertile women with polycystic ovary syndrome.
Franik S, et al. Cochrane Database Syst Rev 2018 - Review. PMID 29797697 Free PMC article.
Aromatase inhibitors (AIs) are a class of drugs that were introduced for ovulation induction in 2001. Since about 2001 clinical trials have reached differing conclusions as to whether the AI letrozole is at least as effective as the first-line treatment clomiphene citrate (CC). OBJECTIVES: To evaluate the effectiveness and safety of aromatase inhibitors for subfertile women with anovulatory PCOS for ovulation induction followed by timed intercourse or intrauterine insemination (IUI). ...
Aromatase inhibitors (AIs) are a class of drugs that were introduced for ovulation induction in 2001. Since about 2001 clinical trial
Effect of Acupuncture vs Sham Acupuncture or Waitlist Control on Joint Pain Related to Aromatase Inhibitors Among Women With Early-Stage Breast Cancer: A Randomized Clinical Trial.
Hershman DL, et al. JAMA 2018 - Clinical Trial. PMID 29998338 Free PMC article.
IMPORTANCE: Musculoskeletal symptoms are the most common adverse effects of aromatase inhibitors and often result in therapy discontinuation. Small studies suggest that acupuncture may decrease aromatase inhibitor-related joint symptoms. OBJECTIVE: To determine the effect of acupuncture in reducing aromatase inhibitor-related joint pain. ...
IMPORTANCE: Musculoskeletal symptoms are the most common adverse effects of aromatase inhibitors and often result in therapy disconti …
Aromatase Inhibitors Evolution as Potential Class of Drugs in the Treatment of Postmenopausal Breast Cancer Women.
Avvaru SP, et al. Mini Rev Med Chem 2018 - Review. PMID 29090666
Aromatase inhibitors are class of drugs that inhibit aromatase, a rate limiting enzyme in the biosynthesis of estrogens from their corresponding androgens. ...The current review deals with recent advances in understanding of aromatase, its mechanism and research in the development of various novel chemotypes as aromatase inhibitors. ...
Aromatase inhibitors are class of drugs that inhibit aromatase, a rate limiting enzyme in the biosynthesis of estrogens from t
The use of aromatase inhibitors in boys with short stature: what to know before prescribing?
Linardi A, et al. Arch Endocrinol Metab 2017 - Review. PMID 28977209 Free article.
Aromatase is a cytochrome P450 enzyme (CYP19A1 isoform) able to catalyze the conversion of androgens to estrogens. The aromatase gene mutations highlighted the action of estrogen as one of the main regulators of bone maturation and closure of bone plate. ...Antiepileptic drugs (lamotrigine, phenobarbital, and phenytoin) also inhibit aromatase. Concomitant use of phenobarbital or valproate has a synergistic effect on aromatase inhibition. ...
Aromatase is a cytochrome P450 enzyme (CYP19A1 isoform) able to catalyze the conversion of androgens to estrogens. The aromatase
Breast Cancer Treatment: A Review
Waks AG and Winer EP. JAMA 2019 - Review. PMID 30667505
Aromatase inhibitors in premenopausal women with breast cancer: the state of the art and future prospects.
Pistelli M, et al. Curr Oncol 2018. PMID 29719441 Free PMC article.
In the past, hormonal treatment consisted only of the estrogen receptor modulator tamoxifen, associated with luteinizing hormone-releasing hormone (lhrh); more recently, aromatase inhibitors (ais) have come into widespread use. ...
In the past, hormonal treatment consisted only of the estrogen receptor modulator tamoxifen, associated with luteinizing hormone-releasing h …
Potent aromatase inhibitors and molecular mechanism of inhibitory action.
Kang H, et al. Eur J Med Chem 2018. PMID 29202405
As well known, aromatase mediates the production of estrogen. Thus, inhibition of aromatase with chemical molecules has been considered to be an effective treatment for estrogen receptor-positive (ER+) breast cancer. ...Analysis of energy of the two compound-aromatase complexes revealed that the 8o has low binding energy (strong binding affinity) to the aromatase as compared to letrozole, which was in accordance with the experimental results. ...
As well known, aromatase mediates the production of estrogen. Thus, inhibition of aromatase with chemical molecules has been c …
Tailoring Adjuvant Endocrine Therapy for Premenopausal Breast Cancer
Francis PA, et al. N Engl J Med 2018 - Clinical Trial. PMID 29863451 Free PMC article.
BACKGROUND: In the Suppression of Ovarian Function Trial (SOFT) and the Tamoxifen and Exemestane Trial (TEXT), the 5-year rates of recurrence of breast cancer were significantly lower among premenopausal women who received the aromatase inhibitor exemestane plus ovarian suppression than among those who received tamoxifen plus ovarian suppression. ...
BACKGROUND: In the Suppression of Ovarian Function Trial (SOFT) and the Tamoxifen and Exemestane Trial (TEXT), the 5-year rates of recurrenc …
Toxicity of Extended Adjuvant Therapy With Aromatase Inhibitors in Early Breast Cancer: A Systematic Review and Meta-analysis.
Goldvaser H, et al. J Natl Cancer Inst 2018 - Review. PMID 28922781
BACKGROUND: A number of randomized controlled trials (RCTs) have reported improvement in breast cancer outcomes from extending treatment with aromatase inhibitors (AIs) beyond the initial five years after diagnosis. ...
BACKGROUND: A number of randomized controlled trials (RCTs) have reported improvement in breast cancer outcomes from extending treatment wit …
6,098 results
Jump to page
Feedback