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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1995 1
1997 8
1998 4
1999 8
2000 11
2001 9
2002 14
2003 12
2004 19
2005 18
2006 20
2007 28
2008 20
2009 22
2010 21
2011 27
2012 31
2013 38
2014 34
2015 37
2016 27
2017 35
2018 31
2019 19
2020 2
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437 results
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Page 1
Structure and dynamics of GPCR signaling complexes.
Hilger D, Masureel M, Kobilka BK. Hilger D, et al. Nat Struct Mol Biol. 2018 Jan;25(1):4-12. doi: 10.1038/s41594-017-0011-7. Epub 2018 Jan 8. Nat Struct Mol Biol. 2018. PMID: 29323277 Free PMC article. Review.
Catalytic activation of β-arrestin by GPCRs.
Eichel K, Jullié D, Barsi-Rhyne B, Latorraca NR, Masureel M, Sibarita JB, Dror RO, von Zastrow M. Eichel K, et al. Nature. 2018 May;557(7705):381-386. doi: 10.1038/s41586-018-0079-1. Epub 2018 May 2. Nature. 2018. PMID: 29720660 Free PMC article.
Cryo-EM structure of human rhodopsin bound to an inhibitory G protein.
Kang Y, Kuybeda O, de Waal PW, Mukherjee S, Van Eps N, Dutka P, Zhou XE, Bartesaghi A, Erramilli S, Morizumi T, Gu X, Yin Y, Liu P, Jiang Y, Meng X, Zhao G, Melcher K, Ernst OP, Kossiakoff AA, Subramaniam S, Xu HE. Kang Y, et al. Nature. 2018 Jun;558(7711):553-558. doi: 10.1038/s41586-018-0215-y. Epub 2018 Jun 13. Nature. 2018. PMID: 29899450
Structural insights into binding specificity, efficacy and bias of a β2AR partial agonist.
Masureel M, Zou Y, Picard LP, van der Westhuizen E, Mahoney JP, Rodrigues JPGLM, Mildorf TJ, Dror RO, Shaw DE, Bouvier M, Pardon E, Steyaert J, Sunahara RK, Weis WI, Zhang C, Kobilka BK. Masureel M, et al. Nat Chem Biol. 2018 Nov;14(11):1059-1066. doi: 10.1038/s41589-018-0145-x. Epub 2018 Oct 16. Nat Chem Biol. 2018. PMID: 30327561 Free PMC article.
GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling.
Thomsen ARB, Plouffe B, Cahill TJ 3rd, Shukla AK, Tarrasch JT, Dosey AM, Kahsai AW, Strachan RT, Pani B, Mahoney JP, Huang L, Breton B, Heydenreich FM, Sunahara RK, Skiniotis G, Bouvier M, Lefkowitz RJ. Thomsen ARB, et al. Cell. 2016 Aug 11;166(4):907-919. doi: 10.1016/j.cell.2016.07.004. Epub 2016 Aug 4. Cell. 2016. PMID: 27499021 Free PMC article.
Molecular mechanism of GPCR-mediated arrestin activation.
Latorraca NR, Wang JK, Bauer B, Townshend RJL, Hollingsworth SA, Olivieri JE, Xu HE, Sommer ME, Dror RO. Latorraca NR, et al. Nature. 2018 May;557(7705):452-456. doi: 10.1038/s41586-018-0077-3. Epub 2018 May 2. Nature. 2018. PMID: 29720655 Free PMC article.
Molecular Mechanisms of GPCR Signaling: A Structural Perspective.
Gurevich VV, Gurevich EV. Gurevich VV, et al. Int J Mol Sci. 2017 Nov 24;18(12):2519. doi: 10.3390/ijms18122519. Int J Mol Sci. 2017. PMID: 29186792 Free PMC article. Review.
Crystal Structure of an LSD-Bound Human Serotonin Receptor.
Wacker D, Wang S, McCorvy JD, Betz RM, Venkatakrishnan AJ, Levit A, Lansu K, Schools ZL, Che T, Nichols DE, Shoichet BK, Dror RO, Roth BL. Wacker D, et al. Cell. 2017 Jan 26;168(3):377-389.e12. doi: 10.1016/j.cell.2016.12.033. Cell. 2017. PMID: 28129538 Free PMC article.
The structural basis of the arrestin binding to GPCRs.
Gurevich VV, Gurevich EV. Gurevich VV, et al. Mol Cell Endocrinol. 2019 Mar 15;484:34-41. doi: 10.1016/j.mce.2019.01.019. Epub 2019 Jan 28. Mol Cell Endocrinol. 2019. PMID: 30703488 Free PMC article. Review.
Structure-inspired design of β-arrestin-biased ligands for aminergic GPCRs.
McCorvy JD, Butler KV, Kelly B, Rechsteiner K, Karpiak J, Betz RM, Kormos BL, Shoichet BK, Dror RO, Jin J, Roth BL. McCorvy JD, et al. Nat Chem Biol. 2018 Feb;14(2):126-134. doi: 10.1038/nchembio.2527. Epub 2017 Dec 11. Nat Chem Biol. 2018. PMID: 29227473 Free PMC article.
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