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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1973 2
1975 8
1976 12
1977 6
1978 1
1979 9
1980 15
1981 15
1982 11
1983 18
1984 30
1985 29
1986 34
1987 39
1988 41
1989 38
1990 40
1991 46
1992 13
1993 37
1994 51
1995 42
1996 21
1997 30
1998 35
1999 46
2000 31
2001 34
2002 20
2003 20
2004 34
2005 18
2006 45
2007 51
2008 54
2009 44
2010 42
2011 42
2012 55
2013 53
2014 69
2015 67
2016 61
2017 71
2018 65
2019 68
2020 75
2021 76
2022 87
2023 100
2024 34

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1,813 results

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Page 1
Neurophysiological symptoms and aspartame: What is the connection?
Choudhary AK, Lee YY. Choudhary AK, et al. Nutr Neurosci. 2018 Jun;21(5):306-316. doi: 10.1080/1028415X.2017.1288340. Epub 2017 Feb 15. Nutr Neurosci. 2018. PMID: 28198207 Review.
We reviewed studies linking neurophysiological symptoms to aspartame usage and conclude that aspartame may be responsible for adverse neurobehavioral health outcomes. ...More research evaluating the neurobehavioral effects of aspartame are required....
We reviewed studies linking neurophysiological symptoms to aspartame usage and conclude that aspartame may be responsible for …
Revisiting the safety of aspartame.
Choudhary AK, Pretorius E. Choudhary AK, et al. Nutr Rev. 2017 Sep 1;75(9):718-730. doi: 10.1093/nutrit/nux035. Nutr Rev. 2017. PMID: 28938797 Review.
Aspartame is a synthetic dipeptide artificial sweetener, frequently used in foods, medications, and beverages, notably carbonated and powdered soft drinks. ...Since aspartame consumption is on the rise, the safety of this sweetener should be revisited. ...
Aspartame is a synthetic dipeptide artificial sweetener, frequently used in foods, medications, and beverages, notably carbonated and
Aspartame-True or False? Narrative Review of Safety Analysis of General Use in Products.
Czarnecka K, Pilarz A, Rogut A, Maj P, Szymańska J, Olejnik Ł, Szymański P. Czarnecka K, et al. Nutrients. 2021 Jun 7;13(6):1957. doi: 10.3390/nu13061957. Nutrients. 2021. PMID: 34200310 Free PMC article. Review.
Aspartame is a sweetener introduced to replace the commonly used sucrose. ...Further research should be conducted to ensure clear information about the impact of aspartame on health....
Aspartame is a sweetener introduced to replace the commonly used sucrose. ...Further research should be conducted to ensure clear inf
Aspartame and cancer - new evidence for causation.
Landrigan PJ, Straif K. Landrigan PJ, et al. Environ Health. 2021 Apr 12;20(1):42. doi: 10.1186/s12940-021-00725-y. Environ Health. 2021. PMID: 33845854 Free PMC article.
There was no evidence of Mycoplasma infection. INTERPRETATION: These new findings confirm that aspartame is a chemical carcinogen in rodents. They confirm the very worrisome finding that prenatal exposure to aspartame increases cancer risk in rodent offspring. ...We …
There was no evidence of Mycoplasma infection. INTERPRETATION: These new findings confirm that aspartame is a chemical carcinogen in …
Aspartame Safety as a Food Sweetener and Related Health Hazards.
Shaher SAA, Mihailescu DF, Amuzescu B. Shaher SAA, et al. Nutrients. 2023 Aug 18;15(16):3627. doi: 10.3390/nu15163627. Nutrients. 2023. PMID: 37630817 Free PMC article. Review.
Aspartame is the methyl-ester of the aspartate-phenylalanine dipeptide. ...It would be also highly desirable for every product containing aspartame to clearly indicate on the label the exact amount of the substance and some risk warnings....
Aspartame is the methyl-ester of the aspartate-phenylalanine dipeptide. ...It would be also highly desirable for every product contai
Transgenerational transmission of aspartame-induced anxiety and changes in glutamate-GABA signaling and gene expression in the amygdala.
Jones SK, McCarthy DM, Vied C, Stanwood GD, Schatschneider C, Bhide PG. Jones SK, et al. Proc Natl Acad Sci U S A. 2022 Dec 6;119(49):e2213120119. doi: 10.1073/pnas.2213120119. Epub 2022 Dec 2. Proc Natl Acad Sci U S A. 2022. PMID: 36459641 Free PMC article.
Even more strikingly, the anxiety-like behavior, its response to diazepam, and changes in amygdala gene expression were transmitted to male and female offspring in two generations descending from the aspartame-exposed males. Extrapolation of the findings to humans suggests …
Even more strikingly, the anxiety-like behavior, its response to diazepam, and changes in amygdala gene expression were transmitted to male …
Aspartame and Risk of Cancer: A Meta-analytic Review.
Mallikarjun S, Sieburth RM. Mallikarjun S, et al. Arch Environ Occup Health. 2015;70(3):133-41. doi: 10.1080/19338244.2013.828674. Arch Environ Occup Health. 2015. PMID: 24965331
Aspartame (APM) is the most commonly used artificial sweetener and flavor enhancer in the world. ...
Aspartame (APM) is the most commonly used artificial sweetener and flavor enhancer in the world. ...
Metabolic effects of aspartame in adulthood: A systematic review and meta-analysis of randomized clinical trials.
Santos NC, de Araujo LM, De Luca Canto G, Guerra ENS, Coelho MS, Borin MF. Santos NC, et al. Crit Rev Food Sci Nutr. 2018;58(12):2068-2081. doi: 10.1080/10408398.2017.1304358. Epub 2017 Aug 18. Crit Rev Food Sci Nutr. 2018. PMID: 28394643
Data about harms or benefits associated with the consumption of aspartame, a nonnutritive sweetener worldwide consumed, are still controversial. ...High-density lipoprotein cholesterol serum levels were higher on aspartame compared to control (-0.03 mmol/L; 95% CI, …
Data about harms or benefits associated with the consumption of aspartame, a nonnutritive sweetener worldwide consumed, are still con …
Aspartame: Should Individuals with Type II Diabetes be Taking it?
Choudhary AK. Choudhary AK. Curr Diabetes Rev. 2018;14(4):350-362. doi: 10.2174/1573399813666170601093336. Curr Diabetes Rev. 2018. PMID: 28571543 Review.
OBJECTIVE: This review consolidates knowledge gained from studies that link aspartame consumption to the various mechanisms associated with T2D. ...CONCLUSION: Aspartame and its metabolites are safe for T2D is still debatable due to a lack of consistent data. ...
OBJECTIVE: This review consolidates knowledge gained from studies that link aspartame consumption to the various mechanisms associate …
Mutagenicity and genotoxicity studies of aspartame.
Otabe A, Ohta F, Takumi A, Lynch B. Otabe A, et al. Regul Toxicol Pharmacol. 2019 Apr;103:345-351. doi: 10.1016/j.yrtph.2018.01.023. Epub 2018 Feb 19. Regul Toxicol Pharmacol. 2019. PMID: 29408486 Free article. Review.
In a bacterial reverse mutation pre-incubation study, Salmonella typhimurium strains TA100, TA1535, TA98, and TA1537 and Escherichia coli WP2 uvrA were treated with aspartame at concentrations of up to 5000 mug/plate with or without metabolic activation and showed no mutag …
In a bacterial reverse mutation pre-incubation study, Salmonella typhimurium strains TA100, TA1535, TA98, and TA1537 and Escherichia coli WP …
1,813 results