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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1949 1
1960 1
1962 1
1965 1
1967 1
1969 1
1973 2
1975 3
1976 1
1977 1
1978 2
1979 2
1980 2
1981 5
1982 1
1983 2
1984 3
1985 1
1986 3
1987 4
1988 3
1989 6
1990 8
1991 3
1992 3
1993 1
1994 2
1995 2
1996 4
1997 4
1998 3
1999 3
2000 2
2001 3
2003 3
2004 6
2005 2
2006 2
2007 2
2008 2
2009 2
2011 2
2012 2
2013 3
2014 5
2015 3
2016 4
2017 4
2018 8
2019 4
2020 4
2021 3
2022 2
2023 4
2024 6

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154 results

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Page 1
Enhanced Cardiomyocyte NLRP3 Inflammasome Signaling Promotes Atrial Fibrillation.
Yao C, Veleva T, Scott L Jr, Cao S, Li L, Chen G, Jeyabal P, Pan X, Alsina KM, Abu-Taha I Dr, Ghezelbash S, Reynolds CL, Shen YH, LeMaire SA, Schmitz W, Müller FU, El-Armouche A, Tony Eissa N, Beeton C, Nattel S, Wehrens XHT, Dobrev D, Li N. Yao C, et al. Circulation. 2018 Nov 13;138(20):2227-2242. doi: 10.1161/CIRCULATIONAHA.118.035202. Circulation. 2018. PMID: 29802206 Free PMC article.
CM-KI mice exhibited ectopic activity, abnormal sarcoplasmic reticulum Ca(2+) release, atrial effective refractory period shortening, and atrial hypertrophy. Adeno-associated virus subtype-9-mediated CM-specific knockdown of Nlrp3 suppressed AF development in CM-KI …
CM-KI mice exhibited ectopic activity, abnormal sarcoplasmic reticulum Ca(2+) release, atrial effective refractory period shortening, and …
Angiotensin II Mediates Cardiomyocyte Hypertrophy in Atrial Cardiomyopathy via Epigenetic Transcriptional Regulation.
Zheng L, Wang J, Zhang R, Zhang Y, Geng J, Cao L, Zhao X, Geng J, Du X, Hu Y, Cong H. Zheng L, et al. Comput Math Methods Med. 2022 Jun 17;2022:6312100. doi: 10.1155/2022/6312100. eCollection 2022. Comput Math Methods Med. 2022. PMID: 35756425 Free PMC article.
AngII induces histone acetylation via the cytoplasmic-nuclear shuttling of HDACs, which constitutes a novel mechanism of atrial hypertrophy regulation and might provide a promising therapeutic strategy for atrial cardiomyopathy....
AngII induces histone acetylation via the cytoplasmic-nuclear shuttling of HDACs, which constitutes a novel mechanism of atrial hy …
TWEAK/Fn14 mediates atrial-derived HL-1 myocytes hypertrophy via JAK2/STAT3 signalling pathway.
Hao L, Ren M, Rong B, Xie F, Lin MJ, Zhao YC, Yue X, Han WQ, Zhong JQ. Hao L, et al. J Cell Mol Med. 2018 Sep;22(9):4344-4353. doi: 10.1111/jcmm.13724. Epub 2018 Jul 4. J Cell Mol Med. 2018. PMID: 29971943 Free PMC article.
This study therefore investigated the effects of Fn14 on atrial hypertrophy and underlying cellular mechanisms using HL-1 atrial myocytes. In patients with AF, Fn14 protein levels were higher in atrial myocytes from atrial appendages, and expression of TWEAK was inc …
This study therefore investigated the effects of Fn14 on atrial hypertrophy and underlying cellular mechanisms using HL-1 atri …
Incidental Finding of Lipomatous Hypertrophy of the Right Atrial Free Wall in an Elderly Female With Severe Pulmonary Hypertension: Early Detection by Multimodality Imaging.
Sonaglioni A, Nicolosi GL, Rispoli GA, Lombardo M. Sonaglioni A, et al. Cureus. 2023 Dec 17;15(12):e50665. doi: 10.7759/cureus.50665. eCollection 2023 Dec. Cureus. 2023. PMID: 38186482 Free PMC article.
Lipomatous atrial hypertrophy (LAH) is a benign cardiac lesion characterized by fat accumulation in the interatrial septum that spares the fossa ovalis. ...
Lipomatous atrial hypertrophy (LAH) is a benign cardiac lesion characterized by fat accumulation in the interatrial septum tha …
Cardiomyocyte and endothelial cells play distinct roles in the tumour necrosis factor (TNF)-dependent atrial responses and increased atrial fibrillation vulnerability induced by endurance exercise training in mice.
Lakin R, Polidovitch N, Yang S, Parikh M, Liu X, Debi R, Gao X, Chen W, Guzman C, Yakobov S, Izaddoustdar F, Wauchop M, Lei Q, Xu W, Nedospasov SA, Christoffels VM, Backx PH. Lakin R, et al. Cardiovasc Res. 2023 Dec 19;119(16):2607-2622. doi: 10.1093/cvr/cvad144. Cardiovasc Res. 2023. PMID: 37713664 Free PMC article.
Tnf excision in atrial cardiomyocytes did, however, prevent atrial hypertrophy, fibrosis, and macrophage infiltration as well as conduction slowing and increased AF susceptibility arising from exercise training. In contrast, endothelial-specific excision only reduce …
Tnf excision in atrial cardiomyocytes did, however, prevent atrial hypertrophy, fibrosis, and macrophage infiltration as well …
Balanced Intense Exercise Training Induces Atrial Oxidative Stress Counterbalanced by the Antioxidant System and Atrial Hypertrophy That Is Not Associated with Pathological Remodeling or Arrhythmogenicity.
Oláh A, Barta BA, Sayour AA, Ruppert M, Virág-Tulassay E, Novák J, Varga ZV, Ferdinandy P, Merkely B, Radovits T. Oláh A, et al. Antioxidants (Basel). 2021 Mar 15;10(3):452. doi: 10.3390/antiox10030452. Antioxidants (Basel). 2021. PMID: 33803975 Free PMC article.
Post-mortem atrial weight data and histological examination confirmed marked atrial hypertrophy. We found increased atrial gene expression of antioxidant enzymes along with increased nitro-oxidative stress. ...Long-term, balanced exercise training-induced atrial …
Post-mortem atrial weight data and histological examination confirmed marked atrial hypertrophy. We found increased atrial gen …
NR4A3 prevents diabetes induced atrial cardiomyopathy by maintaining mitochondrial energy metabolism and reducing oxidative stress.
Peng H, Yuan J, Wang Z, Mo B, Wang Y, Wang Y, Wang Q. Peng H, et al. EBioMedicine. 2024 Aug;106:105268. doi: 10.1016/j.ebiom.2024.105268. Epub 2024 Aug 3. EBioMedicine. 2024. PMID: 39098108 Free PMC article.
FINDINGS: The expression of NR4A3 was significantly decreased in atrial tissues of both AF patients and diabetic mice compared to their respective control groups. NR4A3 deficiency exacerbated atrial hypertrophy and atrial fibrosis, and increased susceptibility to pa …
FINDINGS: The expression of NR4A3 was significantly decreased in atrial tissues of both AF patients and diabetic mice compared to their resp …
Activation of the calcineurin signaling pathway induces atrial hypertrophy during atrial fibrillation.
Bukowska A, Lendeckel U, Hirte D, Wolke C, Striggow F, Röhnert P, Huth C, Klein HU, Goette A. Bukowska A, et al. Cell Mol Life Sci. 2006 Feb;63(3):333-42. doi: 10.1007/s00018-005-5353-3. Cell Mol Life Sci. 2006. PMID: 16389460 Free PMC article.
The impact of the calcium-dependent calcineurin pathway on the development of AF-induced atrial hypertrophy has not yet been analyzed. In this study, atrial tissue samples from patients with sinus rhythm and chronic persistent atrial fibrillation (CAF) were used to …
The impact of the calcium-dependent calcineurin pathway on the development of AF-induced atrial hypertrophy has not yet been a …
Junctophilin-2 expression rescues atrial dysfunction through polyadic junctional membrane complex biogenesis.
Brandenburg S, Pawlowitz J, Eikenbusch B, Peper J, Kohl T, Mitronova GY, Sossalla S, Hasenfuss G, Wehrens XH, Kohl P, Rog-Zielinska EA, Lehnart SE. Brandenburg S, et al. JCI Insight. 2019 Jun 20;4(12):e127116. doi: 10.1172/jci.insight.127116. eCollection 2019 Jun 20. JCI Insight. 2019. PMID: 31217359 Free PMC article.
In contrast, aortic pressure overload resulted in left atrial hypertrophy with decreased junctophilin-2 and RyR2 expression, disrupted axial junctions, and atrial fibrosis. ...Our data show a central role of junctophilin-2 cluster disruption in atrial hype …
In contrast, aortic pressure overload resulted in left atrial hypertrophy with decreased junctophilin-2 and RyR2 expression, d …
Activin Receptor-Like Kinase 4 Haplodeficiency Mitigates Arrhythmogenic Atrial Remodeling and Vulnerability to Atrial Fibrillation in Cardiac Pathological Hypertrophy.
Wang Q, Chen Y, Zhang D, Li C, Chen X, Hou J, Fei Y, Wang Y, Li Y. Wang Q, et al. J Am Heart Assoc. 2018 Aug 21;7(16):e008842. doi: 10.1161/JAHA.118.008842. J Am Heart Assoc. 2018. PMID: 30369314 Free PMC article.
Compared with wild-type littermates, ALK 4(+/-) mice demonstrated a similar extent of atrial hypertrophy but significantly suppressed atrial fibrosis at 8 weeks post-abdominal aortic constriction. ...
Compared with wild-type littermates, ALK 4(+/-) mice demonstrated a similar extent of atrial hypertrophy but significantly sup …
154 results