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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1997 2
1998 3
2000 2
2001 5
2002 16
2003 24
2004 23
2005 28
2006 30
2007 42
2008 47
2009 46
2010 62
2011 62
2012 83
2013 116
2014 150
2015 148
2016 133
2017 123
2018 133
2019 67
2020 1
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1,171 results
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Page 1
Aurora-A Kinase: A Potent Oncogene and Target for Cancer Therapy.
Yan M, Wang C, He B, Yang M, Tong M, Long Z, Liu B, Peng F, Xu L, Zhang Y, Liang D, Lei H, Subrata S, Kelley KW, Lam EW, Jin B, Liu Q. Yan M, et al. Med Res Rev. 2016 Nov;36(6):1036-1079. doi: 10.1002/med.21399. Epub 2016 Jul 13. Med Res Rev. 2016. PMID: 27406026 Free article. Review.
Inhibition of Aurora Kinase A Induces Necroptosis in Pancreatic Carcinoma.
Xie Y, Zhu S, Zhong M, Yang M, Sun X, Liu J, Kroemer G, Lotze M, Zeh HJ 3rd, Kang R, Tang D. Xie Y, et al. Gastroenterology. 2017 Nov;153(5):1429-1443.e5. doi: 10.1053/j.gastro.2017.07.036. Epub 2017 Jul 29. Gastroenterology. 2017. PMID: 28764929 Free PMC article.
Aurora kinase A drives the evolution of resistance to third-generation EGFR inhibitors in lung cancer.
Shah KN, Bhatt R, Rotow J, Rohrberg J, Olivas V, Wang VE, Hemmati G, Martins MM, Maynard A, Kuhn J, Galeas J, Donnella HJ, Kaushik S, Ku A, Dumont S, Krings G, Haringsma HJ, Robillard L, Simmons AD, Harding TC, McCormick F, Goga A, Blakely CM, Bivona TG, Bandyopadhyay S. Shah KN, et al. Nat Med. 2019 Jan;25(1):111-118. doi: 10.1038/s41591-018-0264-7. Epub 2018 Nov 26. Nat Med. 2019. PMID: 30478424 Free PMC article.
Aurora A Kinase Inhibition Is Synthetic Lethal with Loss of the RB1 Tumor Suppressor Gene.
Gong X, Du J, Parsons SH, Merzoug FF, Webster Y, Iversen PW, Chio LC, Van Horn RD, Lin X, Blosser W, Han B, Jin S, Yao S, Bian H, Ficklin C, Fan L, Kapoor A, Antonysamy S, Mc Nulty AM, Froning K, Manglicmot D, Pustilnik A, Weichert K, Wasserman SR, Dowless M, Marugán C, Baquero C, Lallena MJ, Eastman SW, Hui YH, Dieter MZ, Doman T, Chu S, Qian HR, Ye XS, Barda DA, Plowman GD, Reinhard C, Campbell RM, Henry JR, Buchanan SG. Gong X, et al. Cancer Discov. 2019 Feb;9(2):248-263. doi: 10.1158/2159-8290.CD-18-0469. Epub 2018 Oct 29. Cancer Discov. 2019. PMID: 30373917 Free article.
A MYC-aurora kinase A protein complex represents an actionable drug target in p53-altered liver cancer.
Dauch D, Rudalska R, Cossa G, Nault JC, Kang TW, Wuestefeld T, Hohmeyer A, Imbeaud S, Yevsa T, Hoenicke L, Pantsar T, Bozko P, Malek NP, Longerich T, Laufer S, Poso A, Zucman-Rossi J, Eilers M, Zender L. Dauch D, et al. Nat Med. 2016 Jul;22(7):744-53. doi: 10.1038/nm.4107. Epub 2016 May 23. Nat Med. 2016. PMID: 27213815
Switching Aurora-A kinase on and off at an allosteric site.
Bayliss R, Burgess SG, McIntyre PJ. Bayliss R, et al. FEBS J. 2017 Sep;284(18):2947-2954. doi: 10.1111/febs.14069. Epub 2017 Apr 18. FEBS J. 2017. PMID: 28342286 Free article. Review.
The multifaceted allosteric regulation of Aurora kinase A.
Levinson NM. Levinson NM. Biochem J. 2018 Jun 26;475(12):2025-2042. doi: 10.1042/BCJ20170771. Biochem J. 2018. PMID: 29946042 Free PMC article. Review.
Aurora Kinase A Promotes AR Degradation via the E3 Ligase CHIP.
Sarkar S, Brautigan DL, Larner JM. Sarkar S, et al. Mol Cancer Res. 2017 Aug;15(8):1063-1072. doi: 10.1158/1541-7786.MCR-17-0062. Epub 2017 May 23. Mol Cancer Res. 2017. PMID: 28536143 Free PMC article.
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