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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1952 1
1954 1
1955 1
1956 1
1958 1
1963 1
1994 3
1996 1
1997 56
1998 185
1999 161
2000 175
2001 157
2002 158
2003 158
2004 151
2005 136
2006 114
2007 112
2008 94
2009 109
2010 103
2011 83
2012 91
2013 75
2014 57
2015 42
2016 47
2017 36
2018 48
2019 10
2020 0
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2,228 results
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Subtype-specific regeneration of retinal ganglion cells following axotomy: effects of osteopontin and mTOR signaling.
Duan X, et al. Neuron 2015. PMID 25754821 Free PMC article.
In mammals, few retinal ganglion cells (RGCs) survive following axotomy, and even fewer regenerate axons. This could reflect differential extrinsic influences or the existence of subpopulations that vary in their responses to injury. We tested these alternatives by comparing responses of molecularly distinct subsets of mouse RGCs to axotomy. Survival rates varied dramatically among subtypes, with alpha-RGCs (αRGCs) surviving preferentially. ...
In mammals, few retinal ganglion cells (RGCs) survive following axotomy, and even fewer regenerate axons. This could reflect differen …
Ca(2+) mediates axotomy-induced necrosis and apoptosis of satellite glial cells remote from the transection site in the isolated crayfish mechanoreceptor.
Khaitin A, et al. Mol Cell Neurosci 2018. PMID 29225183
Ca(2+) gradually accumulated in glial cells after axotomy. In saline with triple Ca(2+) concentration the axotomy-induced apoptosis of glial cells increased, but spontaneous or axotomy-induced necrosis was unexpectedly reduced. ...Possibly, other Ca(2+) sources such as penetration through the plasma membrane contributed to axotomy-induced apoptosis and necrosis of remote glial cells. ...
Ca(2+) gradually accumulated in glial cells after axotomy. In saline with triple Ca(2+) concentration the axotomy-induced apop …
The axotomy response.
Barron KD. J Neurol Sci 2004 - Review. PMID 15140617
Impact of volumetric muscle loss injury on persistent motoneuron axotomy.
Corona BT, et al. Muscle Nerve 2018. PMID 29144551
To characterize neural dysfunction we quantified motoneuron axotomy, in efforts to understand how this relates to the temporal coordination of neuromuscular and morphological alterations due to injury. ...RESULTS: Significant axotomy of 57-79% of all TA muscle motoneurons was observed through 21 days postinjury, which was coupled with a 45-90% TA maximal torque deficit. ...
To characterize neural dysfunction we quantified motoneuron axotomy, in efforts to understand how this relates to the temporal coordi …
Donor nerve axotomy and axonal regeneration after end-to-side neurorrhaphy in a rodent model.
Wang S, et al. J Neurosurg 2018. PMID 29451448
CONCLUSIONS Axonal regrowth into a nerve graft depends on axotomy of the donor nerve after end-to-side neurorrhaphy. More efficient attraction and an improved structure of the regenerating axons were achieved when a predegenerated nerve graft was used. ...
CONCLUSIONS Axonal regrowth into a nerve graft depends on axotomy of the donor nerve after end-to-side neurorrhaphy. More efficient a …
Red Light Treatment in an Axotomy Model of Neurodegeneration.
Beirne K, et al. Photochem Photobiol 2016. PMID 27276065
We hypothesized that 670 nm light can delay axotomy-induced dendritic pruning in the retinal explant. To test this hypothesis, we monitored the effects of 670 nm light (radiant exposure of 31.7 J cm(-2) ), on RGC dendritic pruning in retinal explants from C57BL/6J mice, at 40 min, 8 h and 16 h post axotomy. For sham-treated retinae, area under the Sholl curve, peak of the Sholl curve and dendritic length at 8 h post axotomy showed statistically significant reductions by 42.3% (P = 0.008), 29.8% (P = 0.007) and 38.4% (P = 0.038), respectively, which were further reduced after 16 h by 40.56% (P < 0.008), 33.9% (P < 0.007), 45.43% (P < 0.006), respectively. ...
We hypothesized that 670 nm light can delay axotomy-induced dendritic pruning in the retinal explant. To test this hypothesis, we mon …
The influence of experimental inflammation and axotomy on leucine enkephalin (leuENK) distribution in intramural nervous structures of the porcine descending colon.
Gonkowski S, et al. BMC Vet Res 2018. PMID 29793486 Free PMC article.
The percentage of leuENK-LI perikarya amounted to 11.48 ± 0.96%, 8.71 ± 0.13% and 9.40 ± 0.76% during colitis, and 6.90 ± 0.52% 8.46 ± 12% and 4.48 ± 0.44% after axotomy in MP, OSP and ISP, respectively. ...Differences in the number of leuENK-LI neurons during inflammation and after axotomy may suggest that the exact functions of leuENK probably depend on the type of pathological factor acting on the intestine....
The percentage of leuENK-LI perikarya amounted to 11.48 ± 0.96%, 8.71 ± 0.13% and 9.40 ± 0.76% during colitis, and 6.90 ± 0.52% 8.46 ± 12% a …
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