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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1915 1
1931 1
1941 1
1942 1
1947 1
1951 2
1953 4
1955 3
1956 2
1957 3
1959 6
1960 3
1961 2
1962 3
1963 4
1964 8
1965 5
1966 8
1967 8
1968 7
1969 11
1970 15
1971 22
1972 63
1973 104
1974 135
1975 429
1976 525
1977 482
1978 439
1979 513
1980 607
1981 688
1982 738
1983 964
1984 1005
1985 1158
1986 1171
1987 1252
1988 1385
1989 1545
1990 1455
1991 1702
1992 1683
1993 1809
1994 1860
1995 1965
1996 1961
1997 1996
1998 1871
1999 1827
2000 1937
2001 1910
2002 1911
2003 2078
2004 2059
2005 2376
2006 2397
2007 2480
2008 2583
2009 2878
2010 3056
2011 3349
2012 3605
2013 3839
2014 4240
2015 4560
2016 4592
2017 4781
2018 5132
2019 5571
2020 6339
2021 7381
2022 7746
2023 7238
2024 7633
2025 2250

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124,544 results

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Page 1
Autologous CD19-Targeted Chimeric Antigen Receptor (CAR)T-Cells as the Future of Systemic Lupus Erythematosus Treatment.
Kambayana G, Surya Rini S. Kambayana G, et al. Curr Rheumatol Rev. 2023 Jun 5;19(3):260-269. doi: 10.2174/1573397119666230214103044. Curr Rheumatol Rev. 2023. PMID: 36786138
Autologous CAR T-cell therapy has garnered considerable interest and is considered a potential treatment option for SLE. CD19+CD20- B cells are thought to play an essential role in the onset and progression of SLE. CD19-targeted CAR T-cells destroy …
Autologous CAR T-cell therapy has garnered considerable interest and is considered a potential treatment option for SLE. CD19+CD20- …
Aptamer Generated by Cell-SELEX for Specific Targeting of Human Glioma Cells.
Lin N, Wu L, Xu X, Wu Q, Wang Y, Shen H, Song Y, Wang H, Zhu Z, Kang D, Yang C. Lin N, et al. ACS Appl Mater Interfaces. 2021 Mar 3;13(8):9306-9315. doi: 10.1021/acsami.0c11878. Epub 2020 Oct 8. ACS Appl Mater Interfaces. 2021. PMID: 33030015
Currently, cell-based Systematic Evolution of Ligands by EXponential enrichment (cell-SELEX) technology is one effective tool to obtain DNA or RNA aptamers capable of differentiating the molecular signatures among different types of cell lines. Using cell- …
Currently, cell-based Systematic Evolution of Ligands by EXponential enrichment (cell-SELEX) technology is one effective tool …
Recent developments in cell-SELEX technology for aptamer selection.
Kaur H. Kaur H. Biochim Biophys Acta Gen Subj. 2018 Oct;1862(10):2323-2329. doi: 10.1016/j.bbagen.2018.07.029. Epub 2018 Jul 27. Biochim Biophys Acta Gen Subj. 2018. PMID: 30059712 Review.
BACKGROUND: SELEX technique is employed to select aptamers against wide range of targets. The in vitro method of aptamer selection using live cells as the target is referred as cell-SELEX. SCOPE OF THE REVIEW: The review provides a comprehensive description o …
BACKGROUND: SELEX technique is employed to select aptamers against wide range of targets. The in vitro method of aptamer selection us …
Research progress of whole-cell-SELEX selection and the application of cell-targeting aptamer.
Duan Y, Zhang C, Wang Y, Chen G. Duan Y, et al. Mol Biol Rep. 2022 Aug;49(8):7979-7993. doi: 10.1007/s11033-022-07317-0. Epub 2022 Mar 10. Mol Biol Rep. 2022. PMID: 35274201 Review.
As a novel method of aptamers screening, whole-cell-SELEX (WC-SELEX) has gained more and more attention in many fields such as biomedicine, analytical chemistry, and molecular diagnostics due to its ability to screen multiple potential aptamers without knowing the d …
As a novel method of aptamers screening, whole-cell-SELEX (WC-SELEX) has gained more and more attention in many fields such as …
CD19(+)CD73(+) B cells infiltration indicates poor prognosis and unfavorable responses to immunotherapy in gastric cancer.
Zhang Y, Wang W, Liu Q, Jiang J, Zhao P, Huang C, Li Y, Fu Y. Zhang Y, et al. Int Immunopharmacol. 2024 Nov 15;141:113002. doi: 10.1016/j.intimp.2024.113002. Epub 2024 Aug 29. Int Immunopharmacol. 2024. PMID: 39213870
The CD19(+)CD73(+) B cells also correlated with the production of immunosuppressive cytokines IL-10 and TGFB1. Further analysis indicated an association between CD19(+)CD73(+) B cells and advanced-stage GC. CONCLUSIONS: The presence of …
The CD19(+)CD73(+) B cells also correlated with the production of immunosuppressive cytokines IL-10 and TGFB1. Further …
Multiple myeloma-initiating cells.
Hosen N. Hosen N. Int J Hematol. 2013 Mar;97(3):306-12. doi: 10.1007/s12185-013-1293-0. Epub 2013 Feb 19. Int J Hematol. 2013. PMID: 23420183 Review.
Some previous studies have reported that CD19(+) clonotypic B cells can serve as MM-initiating cells. However, we and another group have recently showed that CD19(+) B cells from many MM patients do not reconstitute MM disease upon transp …
Some previous studies have reported that CD19(+) clonotypic B cells can serve as MM-initiating cells. However, we and a …
B cell-based therapies in CNS autoimmunity: differentiating CD19 and CD20 as therapeutic targets.
Forsthuber TG, Cimbora DM, Ratchford JN, Katz E, Stüve O. Forsthuber TG, et al. Ther Adv Neurol Disord. 2018 Mar 21;11:1756286418761697. doi: 10.1177/1756286418761697. eCollection 2018. Ther Adv Neurol Disord. 2018. PMID: 29593838 Free PMC article. Review.
Increasing recognition of the role of B cells in the adaptive immune response makes B cells an important therapeutic target in autoimmunity. Numerous current and developmental immunotherapies target B cells for elimination through recogni …
Increasing recognition of the role of B cells in the adaptive immune response makes B cells an important therape …
Host B cells escape CAR-T immunotherapy by reversible downregulation of CD19.
Fioretti S, Matson CA, Rosenberg KM, Singh NJ. Fioretti S, et al. Cancer Immunol Immunother. 2023 Jan;72(1):257-264. doi: 10.1007/s00262-022-03231-3. Epub 2022 Jun 26. Cancer Immunol Immunother. 2023. PMID: 35753001 Free PMC article.
An undesirable consequence of this therapy is that it can also eliminate healthy B cells expressing CD19. Therefore, understanding the dynamics of CD19 expression in B cells under CAR-T cell immunotherapy can help mitigate both escape and …
An undesirable consequence of this therapy is that it can also eliminate healthy B cells expressing CD19. Therefore, un …
Elevated circulating CD19(+)CD24(hi)CD38(hi) B cells display pro-inflammatory phenotype in idiopathic membranous nephropathy.
Deng B, Deng L, Liu M, Zhao Z, Huang H, Tu X, Liang E, Tian R, Wang X, Wang R, Lin H, Yu Y, Peng A, Xu P, Bao K, He M. Deng B, et al. Immunol Lett. 2023 Sep;261:58-65. doi: 10.1016/j.imlet.2023.08.001. Epub 2023 Aug 6. Immunol Lett. 2023. PMID: 37553031
Here, we investigated the frequency and functional changes of circulating CD19(+)CD24(hi)CD38(hi) B cells and evaluated the correlation of CD19(+)CD24(hi)CD38(hi) B cells with clinical features and T helper cell subsets in IMN patients. . …
Here, we investigated the frequency and functional changes of circulating CD19(+)CD24(hi)CD38(hi) B cells and evaluated …
Decreased granzyme B(+)CD19(+)B cells are associated with tumor progression following liver transplantation.
Li H, Li XL, Cao S, Jia YN, Wang RL, Xu WL, Lang R, He Q, Zhu JQ. Li H, et al. Am J Cancer Res. 2021 Sep 15;11(9):4485-4499. eCollection 2021. Am J Cancer Res. 2021. PMID: 34659900 Free PMC article.
Notably, granzyme B(+)CD19(+)B cells directly inhibited the proliferation, migration, and invasion of hepatocellular carcinoma cells. ...In an independent validation cohort, liver transplant recipients with decreased granzyme B(+)CD19(+)B cel
Notably, granzyme B(+)CD19(+)B cells directly inhibited the proliferation, migration, and invasion of hepatocellular ca …
124,544 results
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